Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai Doctors.
Source: Yahoo News
By Panu Wongcha-um
ReutersFebruary 02, 2020
BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new coronavirus with combination of medications for flu and HIV, with initial results showing vast improvement 48 hours after applying the treatment, they said on Sunday.
The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year-old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days.
The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltamivir in large doses.
"This is not the cure, but the patient's condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Kriangska Atipornwanich, a lung specialist at Rajavithi, told reporters.
"The outlook is good but we still have to do more study to determine that this can be a standard treatment."
Read more: https://www.yahoo.com/news/cocktail-flu-hiv-drugs-appears-124753996.html
CaliforniaPeggy
(149,297 posts)applegrove
(118,011 posts)Last edited Mon Feb 3, 2020, 03:41 PM - Edit history (1)
talking to a research lab in saskatchewan and they said even if they quickly develop a new drug specifically for coronavirus they are a year away from public use as there have to be animal, then human trials.
we can do it
(12,116 posts)Mike 03
(16,616 posts)How does ritonavir work?
Ritonavir belongs to a group or class of drugs called protease inhibitors. This drug interferes with an enzyme called protease, which is used by HIV-infected cells to make new viruses. Since ritonavir inhibits, or reduces the activity of this enzyme, this drug causes HIV-infected cells to produce fewer viruses.
www.catie.ca fact-sheets protease-inhibitors ritonavir-norvir
Lopinavir is an antiretroviral protease inhibitor used in combination with ritonavir in the therapy and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS).
pubchem.ncbi.nlm.nih.gov compound Lopinavir
Good news!
ck4829
(34,974 posts)fleur-de-lisa
(14,615 posts)The rest of us have to resort to science and medical advice.
gristy
(10,667 posts)Hope it pans out, or at least leads to a truly effective treatment. Amazing what can be done when the whole world is working together on a problem.
peggysue2
(10,811 posts)Had not heard about the HIV cocktail mix. If we're lucky, this will work on the majority (if not all) of the infected. Last time I checked the John Hopkins map, there were over 14,000 confirmed cases. But several in the medical community have said there could be as many as 75,000 cases in China that have not been reported. There was a definite lag time between early occurrences of infection in late October, November and early December. So, the numbers are very fluid as well as mild cases to severe respiratory infection numbers.
This has definitely been a heads-up on how easily a previously unknown virus could spread and create utter havoc.
bucolic_frolic
(42,663 posts)cannabis_flower
(3,764 posts)It's not killing most people who get it. Most people won't need the treatment. Out of the 14,000 who've gotten it only a few hundred have died.
bucolic_frolic
(42,663 posts)because undiagnosed cases will surface as time moves along, and populations may fare better since everyone knows what to look for now and will seek treatment. Must be a threshold for medicines.
roamer65
(36,739 posts)This virus may not have the resilience level of HIV.
Cocktailing the drugs also probably is the key. Picking up the efficacy of each one in tandem.
NotHardly
(1,062 posts)Blues Heron
(5,898 posts)This seems tin foil hatty to me.