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Stuart G

(38,359 posts)
Sun Feb 2, 2020, 02:43 PM Feb 2020

Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai Doctors.

Source: Yahoo News

By Panu Wongcha-um
Reuters•February 02, 2020

BANGKOK (Reuters) - Thai doctors have seen success in treating severe cases of the new coronavirus with combination of medications for flu and HIV, with initial results showing vast improvement 48 hours after applying the treatment, they said on Sunday.

The doctors from Rajavithi Hospital in Bangkok said a new approach in coronavirus treatment had improved the condition of several patients under their care, including one 70-year-old Chinese woman from Wuhan who tested positive for the coronavirus for 10 days.

The drug treatment includes a mixture of anti-HIV drugs lopinavir and ritonavir, in combination with flu drug oseltamivir in large doses.

"This is not the cure, but the patient's condition has vastly improved. From testing positive for 10 days under our care, after applying this combination of medicine the test result became negative within 48 hours," Dr. Kriangska Atipornwanich, a lung specialist at Rajavithi, told reporters.

"The outlook is good but we still have to do more study to determine that this can be a standard treatment."



Read more: https://www.yahoo.com/news/cocktail-flu-hiv-drugs-appears-124753996.html

16 replies = new reply since forum marked as read
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Cocktail of flu, HIV drugs appears to help fight coronavirus: Thai Doctors. (Original Post) Stuart G Feb 2020 OP
Sounds like it's a start. Get going on whatever studies are needed. n/t CaliforniaPeggy Feb 2020 #1
Good that they are drugs already approved. Some reporter was applegrove Feb 2020 #2
Drigs? we can do it Feb 2020 #15
From Google: Mike 03 Feb 2020 #3
But... but... the QAnon people said to drink bleach to fight coronavirus ck4829 Feb 2020 #4
Bleach only works on the MAGAts. fleur-de-lisa Feb 2020 #6
I'd been thinking about treatment... gristy Feb 2020 #5
Heard they were going to try the one drug formally used for SARS peggysue2 Feb 2020 #7
Doubt they have medicine stock to treat them all bucolic_frolic Feb 2020 #8
From what I've read cannabis_flower Feb 2020 #9
Yes seems to be around 3-4% but hard to tell bucolic_frolic Feb 2020 #10
The anti-HIV drugs are powerful weapons against RNA viruses. roamer65 Feb 2020 #11
Frankly, I'm beginning to believe that what ever got out of their lab was a weaponized HIV virus... NotHardly Feb 2020 #12
You making stuff up or you have a link? Blues Heron Feb 2020 #16
Wow. That is good news! nt SunSeeker Feb 2020 #13
Wouldn't it be the height of irony if AIDS saves the WORLD? not_the_one Feb 2020 #14

applegrove

(118,011 posts)
2. Good that they are drugs already approved. Some reporter was
Sun Feb 2, 2020, 02:58 PM
Feb 2020

Last edited Mon Feb 3, 2020, 03:41 PM - Edit history (1)

talking to a research lab in saskatchewan and they said even if they quickly develop a new drug specifically for coronavirus they are a year away from public use as there have to be animal, then human trials.

Mike 03

(16,616 posts)
3. From Google:
Sun Feb 2, 2020, 03:06 PM
Feb 2020
How does ritonavir work?
Ritonavir belongs to a group or class of drugs called protease inhibitors. This drug interferes with an enzyme called protease, which is used by HIV-infected cells to make new viruses. Since ritonavir inhibits, or reduces the activity of this enzyme, this drug causes HIV-infected cells to produce fewer viruses.
www.catie.ca › fact-sheets › protease-inhibitors › ritonavir-norvir



Lopinavir is an antiretroviral protease inhibitor used in combination with ritonavir in the therapy and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS).
pubchem.ncbi.nlm.nih.gov › compound › Lopinavir


Good news!

gristy

(10,667 posts)
5. I'd been thinking about treatment...
Sun Feb 2, 2020, 03:26 PM
Feb 2020

Hope it pans out, or at least leads to a truly effective treatment. Amazing what can be done when the whole world is working together on a problem.

peggysue2

(10,811 posts)
7. Heard they were going to try the one drug formally used for SARS
Sun Feb 2, 2020, 04:03 PM
Feb 2020

Had not heard about the HIV cocktail mix. If we're lucky, this will work on the majority (if not all) of the infected. Last time I checked the John Hopkins map, there were over 14,000 confirmed cases. But several in the medical community have said there could be as many as 75,000 cases in China that have not been reported. There was a definite lag time between early occurrences of infection in late October, November and early December. So, the numbers are very fluid as well as mild cases to severe respiratory infection numbers.

This has definitely been a heads-up on how easily a previously unknown virus could spread and create utter havoc.

cannabis_flower

(3,764 posts)
9. From what I've read
Sun Feb 2, 2020, 08:40 PM
Feb 2020

It's not killing most people who get it. Most people won't need the treatment. Out of the 14,000 who've gotten it only a few hundred have died.

bucolic_frolic

(42,663 posts)
10. Yes seems to be around 3-4% but hard to tell
Sun Feb 2, 2020, 08:49 PM
Feb 2020

because undiagnosed cases will surface as time moves along, and populations may fare better since everyone knows what to look for now and will seek treatment. Must be a threshold for medicines.

roamer65

(36,739 posts)
11. The anti-HIV drugs are powerful weapons against RNA viruses.
Sun Feb 2, 2020, 09:17 PM
Feb 2020

This virus may not have the resilience level of HIV.

Cocktailing the drugs also probably is the key. Picking up the efficacy of each one in tandem.

NotHardly

(1,062 posts)
12. Frankly, I'm beginning to believe that what ever got out of their lab was a weaponized HIV virus...
Mon Feb 3, 2020, 03:19 AM
Feb 2020
No one shuts borders for 300 deaths in a country of 1.4 billion people. I'm just say'in, 'So,... you trust the Chinese Communist Party? Oh, please.
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