Long time Cat owners Help--Can the kittens be from the same litter?

[hyphenate]

10. Sure

The white gene is not on the same gene as the colorations of all cats--it's a random trait, even so far that a clone of a cat would not be identical to the original cat because of that randomness.

Black (or black dilute, aka gray) and red (or all orange patterns) are both possible even in the same family, and tabby patterns are also pretty much found in all colorations, sometimes very vividly, other times more muter.

It used to be commonly known that calicoes, those with both black and red, were most always female, because both are on the XX chromosone, and as a male only had one x gene, a male would have to be owner of an extra x gene, making them sterile, and xxy.

I've heard that more males are becoming calico, but it's still not a normal coloration.

But yes--the differences you point out are prefectly likely to be from the same litter.