Anxiety Disorders, if you don't read anything else today, READ THIS.

[HysteryDiagnosis]

http://www.lef.org/protocols/emotional_health/anxiety_01.htm


As B-vitamin levels decline, the methylation cycle becomes impaired-leading to a concurrent increase in homocysteine levels (because it is no longer being recycled efficiently) and a disruption in neurotransmitter synthesis. The close relationship between neurotransmitter synthesis and homocysteine formation has lead some researchers to suspect that there is a link between homocysteine and mood. Indeed, studies suggest that levels of homocysteine are an effective marker for B-vitamin status, and that changes in homocysteine levels correlate with changes in mood.

Interestingly, homocysteine levels have predicted duration of PTSD (Levine 2008), suggesting that lowering homocysteine levels through supplementation with B-vitamins might reduce symptoms of mood disorders by freeing up metabolic resources involved in neurotransmission. Other studies have clearly tied genetic abnormalities such as a mutation in the folic acid-activating enzyme, MTHFR, to high homocysteine levels (and increased symptoms of mood disorders). This reinforces the notion that homocysteine metabolism is an important target in psychiatric imbalances (Coppen 2005). Supplementation with homocysteine-lowering B-vitamins was shown to relieve anxiety in 44 women with premenstrual anxiety (De Souza 2000).

Another compound involved in the methylation cycle is S-adenosylmethionine (SAM-e). SAM-e functions to donate methyl groups into the methylation cycle thereby facilitating the formation of neurotransmitters such as dopamine and serotonin. In clinical trials, SAM-e supplementation has been shown to be as effective as tricyclic antidepressants in treating depressive disorders (Papakostas 2009).

Given the role of healthy methylation in maintaining biochemical balances within the central nervous system, a target blood level of less than 7 – 8 µmol/L of homocysteine helps to ensure proper neurotransmitter metabolism and may balance mood during times of stress, depression and anxiety.

[no_hypocrisy]

1. B-supplements instead of Prozac and Valium.

Sounds good to me.

[HysteryDiagnosis]

4. I pray you read the entire thing, it is priceless imho.... n/t

[The Backlash Cometh]

8. Why don't you give us the synopsis.

It's not exactly a pedestrian read.

[HysteryDiagnosis]

9. A few clips will get the idea across, basically this article gives you information that

may help with PTSD, generalized anxiety, depression etc, and most of it you will never hear about from a person schooled at a typical med school, that is the sad fact.

http://www.lef.org/protocols/emotional_health/anxiety_02.htm

Minerals

>>Magnesium. Magnesium deficiency has been linked to anxiety disorders in several clinical studies. In fact, when researchers want to study anxiety disorder, they use mice that have been specifically bred to be magnesium deficient. This model is very effective at inducing anxiety (Sartori 2011).<<

>>In an 8-week study involving 60 schizophrenic patients, 400 mg of theanine was added to standard antipsychotic therapy. The addition of theanine significantly reduced anxiety and improved several other measures of mood beyond what was achievable with pharmaceuticals alone (Ritsner 2011).<<

>>In one double-blind, placebo-controlled and randomized clinical trial, medical students were given either 2.5g/day of omega-3 polyunsaturated fatty acids (PUFAs) or placebo capsules containing the fatty acid profile of a typical American diet. Compared to controls, those students receiving the omega-3 capsules showed a 20% reduction in anxiety (Kiecolt-Glaser 2011). In a double-blind, placebo-controlled study, omega-3 fatty acid supplementation for 3 months reduced anxiety and anger in substance abusers (Buydens-Branchey 2008). Reduced test anxiety and lower levels of the stress hormone cortisol have also been associated with omega-3 supplementation (Yehuda 2005).<<

>>Rhodiola. Rhodiola rosea is a known adaptogen, an herb that helps improve one’s resistance to stress. It has also shown promise in alleviating anxiety disorder. Ten subjects receiving a daily dose of Rhodiola rosea extract for 10 weeks demonstrated significant improvement in symptoms of anxiety (Shevtsov 2003). Another similar 10-week study found that a 340 mg daily dose of Rhodiola rosea extract significantly eased symptoms of generalized anxiety disorder (Bystritsky 2008). Animal studies have found that compounds in Rhodiola rosea help ameliorate the anxiety associated with smoking cessation (Mattioli 2011).<<

[The Backlash Cometh]

10. Thanks! Appreciate it.

[Confusious]

16. If it actually worked

I take a mutlivitamin.

Has b vitamin in it. doesn't do anything for my depression. started taking it a long time before antidepressants.

Learned about magnesium a long time ago. tried it. didn't work.

antidepressants work.


He's another one for you not listed: tuarine. tried it. doesn't work.

[Smarmie Doofus]

2. Kick. I've temporarily misplaced my Thinking Cap.

But I'd like to sink my mixed-metaphorical teeth into this later.

[Sarah Ibarruri]

3. VERY important article! Thanks! nt

[Glorfindel]

5. Recommend

[postulater]

6. For later after coffee

[tridim]

7. Cannabis works too.

At least it did for me. It doesn't take much either.

[BuddhaGirl]

11. recommend!

n/t

[cleanhippie]

12. Are you REALLY using a corporate supplement group as a credible source?

What does that say about YOUR credibility?

[HysteryDiagnosis]

13. Are you really as foolish as you appear??? n/t

[HuckleB]

14. Are you?

Yes, that is rhetorical question.

:rofl:

[BuddhaGirl]

15. thanks for posting

Life Extension has a good track record with the studies they conduct...some of their conclusions are eventually endorsed by the FDA, even.

:hi:

[hedgehog]

17. I found out about a genetic variation that inteferes with this cycle

about a week ago:

http://www.democraticunderground.com/discuss/duboard.php?az=view_all&address=276x11524

Right now we're waiting to hear our daughter's test results. If she's carrying the gene, the rest of us are going to check with our doctors. There are a lot of chronic disorders floating around the family tree that might be caused by something else, but all of them could also be caused by a faulty folic acid metabolism.