Of course, it depends on what you mean by "aliens." Intelligent aliens - maybe not, but primitive aliens, who's to say?
If one means by aliens "virus-like particles" or simple bacteria, it may or may not be true.
I think that life is improbable, not impossible obviously, but improbable. The already low probability of life occurring is raised and not diminished by having having a large area over which it can arise, and is raised even higher by something like panspermia, in which certain very simple extremophiles - extremophiles being present on the earth - manage to survive in intragalactic space. We do know that life arose on this planet with amazing speed. One possible explanation for this speed is of course that the universe was seeded, not by creatures in space ships, but by tiny packets of self organizing molecules, catalytic nucleic acids.
I have no doubt that this is possible. This is different from asserting a certainty, but on the other hand, I certainly don't think the question absurd. Indeed at least one organism with extreme Resistance to radiation, something an interplanetary traveler would need, is known: Deinococcus radiodurans.
http://web.umr.edu/~microbio/BIO221_2000/Deinococcus_radiodurans.htmlFurther exploration of planetary space, robots to places like Europa and Mars may offer some positive evidence of panspermia, although negative results will not disprove the panspermia hypothesis.
By the way, I hate to find myself agreeing with the retarded science fiction writer Crichton - who follows in the steps of that other great science fiction writer L. Ron Hubbard in being totally out to lunch - but I do think the Drake equation is just shy of nonsense, since it will indeed proved very difficult to get any measurement of any of the variables. Therefore the whole equation is just formalized speculation.