IV: The Right of the people to be secure in their persons, houses, papers and effects, against "unreasonable" searches and seizures, shall not be violated, and no warrants shall issue but upon probable cause, supported by oath or affirmation, and particularly describing the place to be searched, and the persons or things to be seized.
There is nothing reasonable about drug forfeiture laws and they're totally invasive.
V: No person shall be held to answer for a capital or other infamous crime unless on a presentment or indictment of a Grand Jury, except in cases arising in the land or naval forces, or in the militia, when in actual service, in time of war or public danger; nor shall any person be subject for the same offense to be twice put in jeopardy of life or limb; nor shall be compelled in criminal case to be a witness against him self, nor be deprived of life, liberty or property without due process of law; nor shall private property be taken for public use without just compensation.
Forced urine, blood, DNA or breathalyser tests are a form of self-witnessing, you can't be forced to get on the stand and say I smoked a doobie but they can take it via your blood or urine.
VIII: Excessive bail shall be required, nor excessive fines imposed nor cruel and unusual punishments inflicted.
Again this pertains to draconian forfeiture laws, not to mention imprisonment for trivial offense.
IX: The enumeration of certain rights shall not be construed to deny or disparage others retained by the people.
The Fourth Amendment implies a right to privacy and the Ninth Amendment adds leverage to that implication. The people have an inalienable right to privacy and the pursuit of happiness, so long as they're not directly harming others.
The so called "War on Drugs" has been a total rape of the Constitution and I haven't even brought up the continued encroachment against the 10th Amendment using the fig leaf of the Commerce Clause, when no commerce is involved.
There is one common denominator behind this erosion of both the people's and states rights, that being the ascendancy of corporate supremacy; and that cuts across racial lines.