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Legalize it and you:
Obviously eliminate the legal for the most part. (Minors?)
The medical aspects tend to be related to detoxification and malnutrition, and coexisting mental disorders, caused or made worse by drugs.
Most of the social aspects are related to secrecy, and legality.
Cultural has to do with stigma among other aspects central to a specific culture. (ie. Meth is a predominantly lower to middle class white person's drug, crack has been predominantly a lower to middle class black person's drug. (these are sterotypical but generally hold water)
The spiritual aspects have to do with attachment and dependency, do you depend on drugs, or on yourself, or a higher power, or a group, for your strength.
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