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'Ebola' is both the common term used to describe a group of viruses belonging to genus Ebolavirus, family Filoviridae, and the common name for the disease which they cause, Ebola hemorrhagic fever.
The viruses are characterised by a long, filamentous morphology and surrounded by a lipid viral envelope.
Ebolaviruses are morphologically similar to the Marburg virus, also in the family Filoviridae, and share similar disease symptoms. It has caused a number of serious and highly publicized outbreaks since its discovery, as well as featuring as the gruesome antagonist in many forms of entertainment.
Ebola is believed to be a zoonotic virus. Despite considerable effort by the World Health Organization no animal reservoir capable of sustaining the virus between outbreaks has been identified. However, it has been hypothesized that the most likely candidate is the fruit bat.
In the absence of knowing where the reservoir lies, the World Health Organization has taken serious steps to ensure that all known Biosafety Level 4 agents (including Ebola) are carefully and properly contained.
Ebola hemorrhagic fever is potentially lethal and encompasses a range of symptoms including vomiting, diarrhea, general body pain, internal and external bleeding, and fever. Mortality rates are generally high, ranging from 50% - 90%, with the cause of death usually due to hypovolemic shock or organ failure.
Because Ebola is potentially lethal and since no approved vaccine or treatment is available, Ebola is classified as a biosafety level 4 agent, as well as a Category A bioterrorism agent by the Centers for Disease Control and Prevention.
It has the potential to be weaponized for use during biological warfare and was investigated for this particular use by both the Soviet Union and the United States during the Cold War. Its efficacy as a biological-warfare agent is compromised by its extreme lethality and its quickness: a typical outbreak spreads through a small village or hospital, kills everyone there, and runs out of potential hosts, burning out before it reaches a larger community.
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