BACKGROUND: Observational studies suggest that male circumcision may provide protection against HIV-1 infection.
A randomized, controlled intervention trial was conducted in a general population of South Africa to test this hypothesis. CONCLUSION:
Male circumcision provides a degree of protection against acquiring HIV infection, equivalent to what a vaccine of high efficacy would have achieved. Male circumcision may provide an important way of reducing the spread of HIV infection in sub-Saharan Africa. (Preliminary and partial results were presented at the International AIDS Society 2005 Conference, on 26 July 2005, in Rio de Janeiro, Brazil.).
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16231970&query_hl=1&itool=pubmed_docsum