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One of the few studies with L-Glutamine and growth hormone levels is the one conducted by Thomas C. Welbourne at Lousiana State University in 1995. According to his findings, only 2 gms. of oral glutamine was able to raise hormone levels up to 4 times compared to placebo. Furthermore, his surprising study showed that it raised hormone levels for all age groups. But this study involved such a small number of individuals that it isn't generally given that much weight. I don't think I've noted any other major peer-reviewed studies of glutamine and its effect on hormone levels.
Injectible amino acids such as L-arginine and L-lysine can dramatically raise growth hormone levels in children. However, these studies involve massive amounts of approximately 30 grams injected at a time. Before actual hGH could be synthesized, parents (especially in Europe) would have their children take amino acid injections to stimulate taller growth by stimulating the pituitary gland to produce growth hormone. But this effect wears off in later years. Orally taken amino acids, which often include a stack containing l-glutamine, despite all the hype are not that effective in raising hGH levels, the effects don't work at all on older adults, and even on the young, the effects seem to wear off over time.
The only dangers I can see in over-stimulating the body to produce growth hormone (if that is your interest in taking L-glutamine) is the possibility of acromegaly (the opposite of dwarfism) where one becomes a giant. I think the actor who played Lurch suffered from this. There is also some supposed evidence that cancer can result from massive amounts of increased growth hormone. Neither of these possibilities seem likely from just taking reasonable doses of oral L-glutamine, especially if you are older than 18 years old.
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