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n2doc Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 02:44 PM
Original message
Parkinson's partially linked to pesticides
UCLA researchers have provided strong new evidence linking at least some cases of Parkinson's disease to exposure to pesticides. Researchers have suspected for some time that pesticides may cause the neurodegenerative disorder, and experiments in animals have shown that the chemicals, particularly the fungicide maneb and the herbicide paraquat, can cause Parkinson-like symptoms in animals. But proving it in humans has been difficult because of problems in assessing exposure to the agents.

Parkinson's is a disorder of the central nervous system that often impairs the sufferer's motor skills, speech and other functions. It is not fatal of itself, but complications often are. The disease has been recognized since the Middle Ages but became more prevalent in the 20th century. As many as 180 of every 100,000 Americans develop it.

To explore a potential connection to pesticides, epidemiologist Beate Ritz of UCLA and her graduate student Sadie Costello, now at UC Berkeley, studied public records of pesticide applications in California's Central Valley from 1974 to 1999. Every application of pesticides to crops must be registered with the state. Working with Myles Cockburn of USC, they developed a tool to estimate pesticide exposure in areas immediately adjacent to the fields.

They reported in the current issue of the American Journal of Epidemiology that people who lived next to fields where maneb or paraquat had been sprayed were, on average, about 75% more likely to develop the disease. But those who developed the early-onset form of the disease -- contracting it before the age of 60 -- had double the risk of contracting it if they were exposed to either maneb or paraquat alone and four times the risk if they were exposed to both. In most cases, the exposure occurred years before the onset of the disease. Exposure to other pesticides did not appreciably alter the risk.

http://latimesblogs.latimes.com/booster_shots/2009/04/parkinsons-partially-linked-to-pesticides.html
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no_hypocrisy Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 02:49 PM
Response to Original message
1. I heard that malathion contributed to Parkinson's (another pesticide).
Edited on Sun Apr-19-09 02:52 PM by no_hypocrisy
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jwirr Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 02:52 PM
Response to Original message
2. This cannot be totally true because our family had several branches
that had parkinson's in the 1890s.
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GoesTo11 Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 02:54 PM
Response to Reply #2
3. Check out your logic
Partially linked means you could have Parkinsons without it, but it could also cause it.
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hedgehog Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 03:03 PM
Response to Reply #2
5. Depending on where your family lived, they may well have been exposed to other
noxious chemicals coming from, for example, the burning of coal.
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jwirr Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 03:14 PM
Response to Reply #5
6. Rural Illinois.
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hedgehog Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 04:15 PM
Response to Reply #6
10. Don't forget the coal burning stoves in the kitchen and parlor.
Even wood smoke has contaminants.
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proud2BlibKansan Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 02:55 PM
Response to Original message
4. My dad grew up in western Kansas in a small town that was surrounded by wheat fields
When he was diagnosed with Parkinsons (about 25 years ago) the doctors told him they suspected exposure to agricultural chemicals as a child.
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Psychic Consortium Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 03:19 PM
Response to Original message
7. We live in a toxic soup
brought to you by corporate and military interests.

Obama will work on bringing our children clean food, air and water along
with education and health care.

Generations to come will thank him. We will be a smarter and healthier
people as result of Mr. Obama's work.
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kimmerspixelated Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 04:35 PM
Response to Reply #7
11. Well said!
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HysteryDiagnosis Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 03:22 PM
Response to Original message
8. People who develop parkinsons often have a weak or ineffective
Edited on Sun Apr-19-09 03:22 PM by HysteryDiagnosis
form of the super-oxide-dismutase thingy... making it more difficult for them to clear stale neurotransmitters as well as pesticides from the brain.

http://www.lef.org/protocols/neurological/parkinsons_disease_01.htm


http://www.vitaminshoppe.com/store/en/browse/sku_detail.jsp?id=VS-1039
Super Oxide Dismutase (FROM FREEZE DRIED LIVER POWDER)

2664 Mcrdun

N/A*

http://www.ncbi.nlm.nih.gov/pubmed/18808763?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
1: Rev Neurol (Paris). 2009 Jan;165(1):15-30. Epub 2008 Jun 24.Click here to read Links
Parkinson disease and amyotrophic lateral sclerosis. Tauopathies, TDP-43 and SOD mutations
Article in French

Le Forestier N, Lacomblez L, Meininger V.

Pôle neurologique, fédération des maladies du système nerveux, hôpital de la Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France. nadine.leforestier@psl.aphp.fr

In addition to a large number of clinical descriptions of atypical cases, recent pathological, biochemical and genetic studies challenge the view that amyotrophic lateral sclerosis (ALS) is a disorder restricted to the pyramidal motor system. Relations between ALS, Parkinson disease, fronto-temporal dementia, progressive supranuclear paralysis, and cortico-basal degeneration have now been identified. We propose a review of the topic and discuss the contribution of various clinical and pathological features leading to consider motoneuron diseases as neurodegenerative processes included in a broad spectrum of tauopathies.
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azul Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 03:58 PM
Response to Original message
9. Imagine an economic racket where people getting sick and dying
expensively benefits a powerful, monstrous healthcare industry.

What if epidemiology could tell the real story of dangerous chemicals in food and water and air that are poisoning people, would the truth get traction in a media where the agriculture and medical and drug industries have so much advertising clout? Who would fund the epidemiological studies, academia, government? No conflict with business ties there?

The incentive is to not be held liable and make quick profits for the chemical and agriculture businesses which dovetails nicely with healthcare's incentive to treat rather than cure of prevent disease.


The real losers are the people sacrificed in this money making racket. They are kept in the dark and fed BS and more toxic stuff. People are valuable to the system only as far as they can lose their savings and go into debt to pay the medical and drug bills, or to have governments borrow or pay for these bills for their citizens.



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kimmerspixelated Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Apr-19-09 04:39 PM
Response to Reply #9
12. Touche'!
Mainstream Medicine is a sickness industry, to call themselves a health industry is a farce.
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