Studies indicating that marijuana may kill cancer cells doesn't mean that it is beneficial to smoke

[usregimechange]

WASHINGTON (AFP) — The main chemical in marijuana appears to aid in the destruction of brain cancer cells, offering hope for future anti-cancer therapies, researchers in Spain wrote in a study released Thursday.

The authors from the Complutense University in Madrid, working with scientists from other universities, found that the active component of marijuana, tetrahydrocannabinol (THC), causes cancer cells to undergo a process called autophagy -- the breakdown that occurs when the cell essentially self-digests.

The research, which appears in the April edition of US-published Journal of Clinical Investigation, demonstrates that THC and related "cannabinoids" appear to be "a new family of potential antitumoral agent."

The authors wrote that the chemical may prove useful in the development of future "antitumoral agents."

The scientists conducted their research on mice, first stimulating the growth of cancer in the lab animals, then injecting them with a daily dose of THC near the site of their tumors.

The researchers also analyzed the tumors of two patients in an experimental trial looking at the effects of THC on a highly aggressive form of brain tumor, and saw findings "in line with the preclinical evidence" first observed in the laboratory mice.

http://www.google.com/hostednews/afp/article/ALeqM5hI48Z7hVlUKCQa6mLariCgrgBnyg


In other words, according to the research if cannabinoids are applied locally to a tumor it may result in cell death thereby killing the tumor. Now before you light up or otherwise start to view cannabis inhalation as healthy you might realize first that when you smoke it, it is not applied locally to a tumor but rather generally or systematically. If cannabinoids can kill tumor cells, it may not then follow that they are healthy for regular noncancerous cells.

[Webster Green]

1. Your headline is mis-leading, should be brain-cancer cells..(n/t)

[shanti]

22. i was just going to mention

bob marley. it sure didn't help HIM with his cancer :(

come to think of it, i personally knew 2 rastas who have died from brain cancer in the last 3 years, both heavy duty smokers.

[Webster Green]

24. Very sad, that!

I miss him quite a lot. Glad I saw him live in concert. I'll never forget it. :hippie:

[LooseWilly]

75. Funny, I thought Bob Marley died of complications of gangrene

from a toe injury playing soccer, which went gangrenous... and his Rastafarianism prohibited having the toe amputated.

I've never heard of Bob Marley having cancer...

[shanti]

79. no

he had injured a toe playing soccer, and it never really healed. somehow it became cancerous, and the cancer metastasized to his brain, which killed him.

[aquart]

2. Edit the title.

[usregimechange]

9. Edited, thanks.

[Webster Green]

13. Yeah, but you added your own opinion to the headline..

I mean, you are entitled to your opinion, but don't pretend that the study indicated that.
:wtf:

[usregimechange]

15. Hey, I like your Marley avatar. I said "may" because the study indicated cell death from its

application. But that wasn't accurate so I edited it. It could be that the chemical kills cancer cells and is beneficial for regular cells. I doubt it but it is possible.

[Webster Green]

21. Steal the avatar, if you like..

I'm convinced pot is generally a good thing. It is nice to see fresh research being done, as we've been handed such a load of bullshit for the last 70 years or so.

I know that pot has actually made me smarter. (as well as more of a smart-ass) }(

[usregimechange]

23. Compared to other legal substances you are right. Pot has no business as a Schedule I controlled

substance. But because it is not as bad as other drugs doesn't make it the same as an apple.

[LooseWilly]

78. How about an apple that is smoked?

Or smoking the Bible?, as my brother likes to say...

Pot isn't particularly bad for one, as far as I've been able to tell... though I'm not a great personal fan of its effects... but it's only the smoking part that is actually health-wise detrimental as far as I know.
Ohh, and it's legal use in Holland doesn't seem to have any particular downside, from what I've seen.

So all told, I'd say pot may not be the same as an apple, but it's probably healthier than a pork chop. Though, personally, I prefer pork chops...

[dysfunctional press]

29. speaking of marley...didn't he die from a cancerous brain tumor...?

:shrug:
just sayin' is all...

if anyone should have been protected against it by weed- he would have been the guy.

[ohheckyeah]

33. Yes he certainly did.

The article does not indicate how the marijuana was delivered in the study with humans.

[marmar]

3. You might want to tweak your headline a bit.....

n/t

[rcrush]

4. Your headline made me rage with anger

[Gregorian]

10. It had me in a panic.

Phew.

[wildbilln864]

5. Oh!?

This article disagrees!

snip/
"A synthetic chemical similar to the active ingredient in marijuana makes new cells grow in rat brains. What is more, in rats this cell growth appears to be linked with reducing anxiety and depression. The results suggest that marijuana, or its derivatives, could actually be good for the brain."

[scarletwoman]

11. Read the article in the OP - it's about marijuana destroying brain CANCER cells, not brain cells. nt

[wildbilln864]

19. Okay, lol.

Thread topics like that just get under my skin. I ass/u/me too much, lol.
:hi:

[usregimechange]

12. I wonder what would happen if HU210 were injected into cancer cells?

[scarletwoman]

6. You might want to add the word "cancer" to your subject line.

Right now it looks like it says marijuana destroys brain cells -- not exactly the sentiment you intended to convey, I presume?

sw

[Warpy]

7. Please insert the operative word: brain CANCER cells.

It makes all the difference between an honest post and one that supports the anti pot crusaders.

[pscot]

8. That's why you should never

drink absinthe while high on weed. True fact.

[kid a]

14. now you tell - that might have helped twenty years ago!

[wildbilln864]

16. also...

video link :hi:
also see: "Run from the Cure: The Rick Simpson Story"

[NoodleyAppendage]

17. So...the brain cancer cells get the "munchies" real bad. n/t

J

[Zhade]

18. Complete fucking bullshit. There is ZERO EVIDENCE it kills healthy brain cells.

For fuck's sake, medical science proves it's beneficial and STILL the uniformed go out of their way to spin it to say it's harmful.

The facts do not support your nonsense assertion. Period.

[usregimechange]

20. Yes, I am sure inhaling smoke is 100% healthy.

:eyes:

[tritsofme]

26. Smoking isn't the only way to consume cannabis.

The most common by far, but other healthier methods of consumption do exist.

[Starbucks Anarchist]

28. That explains why Willie Nelson and Tommy Chong are dead.

Oh, wait...

[usregimechange]

36. I didn't say it was so lethal that it would show up in a sample of two people

I didn't say it was lethal at all. Kindly do not distort what I said.

[Zhade]

31. My doctors sure don't seem to have a problem with it.

Here's some info for you, free of charge: mj smoke is a bronchial dilator -- mj used to be prescribed to asthmatics to HELP THEM BREATHE. Tobacco smoke, on the other hand, is a bronchial constrictor.

Get some education. You're embarrassing yourself with your patent ignorance of the facts.

[usregimechange]

37. Sorry, but I do not just read only the research that confirms a belief I had to begin with

[usregimechange]

43. Cannabis smoke also contains respiratory irritants, what is the net effect?

[dysfunctional press]

34. not all smoke is created equal.

you cannot equate cigarette smoke with pot smoke.

as a bronchial dilator, pot makes it easier to breathe by smoking it- that's why it was once prescribed to asthmatics. combined with the coughing it brings on, it also helps to clean out the airways.
cigarette smoke acts as a vascular constrictor, achieving a lot of the opposite effects.


and you can also choose to filter/cool the smoke with a water-pipe, or use a vaporizer.

[usregimechange]

39. Did you read all of the studies or just the ones you liked?

It was concluded that the bronchodilator properties of THC do not protect
against the development of AHR in smokers of both tobacco and marijuana.
In contrast, these data suggest that respiratory irritants within marijuana
smoke (including THC and possibly other cannabinoids) augment the effect
of tobacco in increasing airways reactivity. These findings are consistent
with histopathologic evidence of an additive effect of marijuana plus tobacco
in causing tracheobronchial epithelial injury.

http://www.drugabuse.gov/pdf/monographs/99.pdf

[dysfunctional press]

44. this study sounds like it's more about the tobacco smoke...

not all pot smokers also smoke tobacco- ESPECIALLY in the u.s.

in some countries the idiots actually MIX the two to roll a joint...ick.

i don't use tobacco in any form for any reason(that i'm aware of)

[spag68]

25. Pot

I don't know what it's done to me, but I have been smoking it since 1960. The US Navy was kind enough to take me to Columbia and through the Panama Canal to Balboa. Two different kinds of pot and I've been smoking on and off ever since. I've had breaks of two or more years a number of times, with no bad effects. This I can tell you, the bs about how powerful pot is now is just that BS.Now at 67, I would rather smoke then take the pills I am prescribed. I know it's only anecdotal, but I'm still here, still active and still do crossword puzzles, read 6 newspapers a day . Still ride a motorcycle, which I will not do on the pills, but find really relaxing to do after a doobie. I really don't care what they say, it just hasn't harmed me in any discernible way. Any one that drinks alcohol should just STFU about pot.

[wildbilln864]

27. I'm with you spag. nt

:hi:

[dysfunctional press]

30. bob marley died from a cancerous brain tumor...

for what it's worth. :shrug:

[ohheckyeah]

32. Actually the article

doesn't specify the delivery method for humans.

[usregimechange]

35. Nor did I say it did.

[devilgrrl]

38. Smoke?

[Canuckistanian]

40. Wow, that's a powerfully qualified headline

I'll be sure not to smoke that deadly marijuana.

Thanks for the carefully concealed warning.

[usregimechange]

41. Anther strawman, nothing was said about lethality

[Canuckistanian]

45. I know, I'm sorry

You were pressured to change your OP.

And I understand your point about "self-medicating"

Bad joke gone wrong.

[usregimechange]

42. What I actually said: "doesn't mean that it is beneficial to smoke"

[dysfunctional press]

46. you do realize that there are ZERO documented cases of pot smoking causing cancer, right...?

and people have been smoking it for a LONG time.

[usregimechange]

47. I know that studies on it causing cancer have been mixed

but what I suggested is that the study we were discussing does not mean what some were suggesting it means, that it is good for you generally. I am for drug law reform but not for treating cannabis like it were broccoli.

[dysfunctional press]

51. it can be good for you, it depends on a lot of things, as well as how it's ingested.

and especially if you look at the entire hemp plant, and not just marijuana.

but even marijuana is "good" for a lot of people.
i have a painful autoimmune condition, ankylosing spondylitis, that causes a slow fusion of the spine, and other joints and ligaments. for a long time before i received a proper diagnosis, pot was my only real 'medication'. and it still has an important part in my treatment regimen. because my ribs are fused to my spine and rendered inflexible, they constrict my lungs from fully inflating, so the bronchial dilator properties help me to breathe much easier.
much of my pain is derived from inflammation- my sed rate has been into the mid-90's... and it often feels like a pipe clamp is being applied to my spine, so the anti-inflammatory and pain-relief properties are greatly appreciated.
and the general euphoric feeling is something that a long-term chronic-pain patient can use as much of as they can get.
and i do.

as for what general "good" it may do for the general population- until researchers are able to study it freely and thoroughly, and derive and refine products from it- you can't honestly say that it ISN'T at least as good(if not better) for you than broccoli. it still remains to be seen.

[Hanse]

52. True.

Of course, many of the chemicals in marijuana smoke are known carcinogens, and the same ones in tobacco smoke.

This isn't exactly rocket science.

[dysfunctional press]

53. most of the worst things in cigarette smoke were put there by tobacco companies...

and aren't in pot.

you'd think that in all these many many years of pot-smoking by many many people, if it WERE cancer-causing- there would have been at least ONE case where it could be attributed to it...

it could also be that other chemicals/compounds in the pot smoke negate the carcinogenic qualities of the others.
until it can be more freely researched and studied, we may not know.

[Hanse]

54. Well that's a load of malarkey.

The worst things in tobacco smoke are caused by the incomplete combustion of plant material.

The same thing which occurs from smoking marijuana.

"you'd think that in all these many many years of pot-smoking by many many people, if it WERE cancer-causing- there would have been at least ONE case where it could be attributed to it..."

Or, given the prevalence of far more common lung cancer causes, it could just go unnoticed.

"it could also be that other chemicals/compounds in the pot smoke negate the carcinogenic qualities of the others."

The cancer chemopreventatives just cancel out the carcinogens like matter and anti-matter? No, sorry. Toxicology doesn't work that way.

It's entirely possible that cannabinoids are good cancer drugs. But if it turns out that they are, you'd extract the drug and give that to the patient. You wouldn't mix it with a bunch of known carcinogens.

[dysfunctional press]

55. you're entitled to your opinion...

but that's all it is.

[Hanse]

57. Right, but it's an opinioned weighted with scientific knowledge.

As opposed to wishful thinking.

[dysfunctional press]

58. not as far as i can see.

my own opinion comes from LOTS of research, combined with plenty of empirical data.

[Hanse]

60. I don't see much evidence of that.

[dysfunctional press]

62. the only 'wishful thinking' i see going on is on your part...

wishing there was a valid reason to keep pot illegal and out of the hands of those who enjoy it.

[Hanse]

67. Sorry, big mistake.

As an avid recreational marijuana smoker I fully support legalizing marijuana, and I believe recreational smoking is a valid reason in and of itself for recreational smoking.

And as a natural products chemist, with a close colleague and coworker among leaders in the field of cannabinoids, I feel I can go ahead and support marijuana legalization without being intellectually dishonest about it.

[dysfunctional press]

68. then why are you being so intellectually dishonest here?

:shrug:

[Hanse]

70. I'm not.

Everything I've said is true.

[dysfunctional press]

71. why'd you skip the tsna's?

:shrug:

[Hanse]

72. Because they're relatively minor in comparison to acrolein.

[dysfunctional press]

73. really...?

Acrolein is not a suspected human carcinogen; no studies have been conducted on the carcinogenic effects of acrolein on humans, but studies on rats have shown an increase in cancerous tumors from ingestion, but not from inhalation.

hmmm.

[Hanse]

74. You really shouldn't cut and paste from wikipedia.

Especially when arguing with a leading expert on the subject of acrolein.

If you want a quick, simple reference, here you go.

http://digg.com/health/Acrolein_Scientists_Identify_Potent_Tobacco_Carcinogen?FC=PRCK2

Or I could give you a few dozen proper scientific citations when I get back to work on monday, if you'd like.

[dysfunctional press]

76. how about the government then...?

http://www.atsdr.cdc.gov/tfacts124.html#bookmark06

Agency for Toxic Substances and Disease Registry

How likely is acrolein to cause cancer?

The Department of Health and Human Services (DHHS) has not classified acrolein as to its carcinogenicity. The International Agency for Research on Cancer (IARC) has determined that acrolein is not classifiable as to carcinogenicity in humans. The EPA has stated that the potential carcinogenicity of acrolein cannot be determined based on an inadequate database.

but if you say that you're a leading expert...you probably already knew that

[dysfunctional press]

77. btw- what makes 'digg' more authoritative than wikpedia?

:shrug:

[dysfunctional press]

56. the list.

http://quitsmoking.about.com/cs/nicotineinhaler/a/cigingredients.htm

What's in a cigarette?
The list of 599 additives approved by the US Government for use in the manufacture of cigarettes is something every smoker should see. Submitted by the five major American cigarette companies to the Dept. of Health and Human Services in April of 1994, this list of ingredients had long been kept a secret.

Tobacco companies reporting this information were:

American Tobacco Company
Brown and Williamson
Liggett Group, Inc.
Philip Morris Inc.

The List of Additives A through C

* Acetanisole
* Acetic Acid
* Acetoin
* Acetophenone
* 6-Acetoxydihydrotheaspirane
* 2-Acetyl-3- Ethylpyrazine
* 2-Acetyl-5-Methylfuran
* Acetylpyrazine
* 2-Acetylpyridine
* 3-Acetylpyridine
* 2-Acetylthiazole
* Aconitic Acid
* dl-Alanine
* Alfalfa Extract
* Allspice Extract,Oleoresin, and Oil
* Allyl Hexanoate
* Allyl Ionone
* Almond Bitter Oil
* Ambergris Tincture
* Ammonia
* Ammonium Bicarbonate
* Ammonium Hydroxide
* Ammonium Phosphate Dibasic
* Ammonium Sulfide
* Amyl Alcohol
* Amyl Butyrate
* Amyl Formate
* Amyl Octanoate
* alpha-Amylcinnamaldehyde
* Amyris Oil
* trans-Anethole
* Angelica Root Extract, Oil and Seed Oil
* Anise
* Anise Star, Extract and Oils
* Anisyl Acetate
* Anisyl Alcohol
* Anisyl Formate
* Anisyl Phenylacetate
* Apple Juice Concentrate, Extract, and Skins
* Apricot Extract and Juice Concentrate
* 1-Arginine
* Asafetida Fluid Extract And Oil
* Ascorbic Acid
* 1-Asparagine Monohydrate
* 1-Aspartic Acid
* Balsam Peru and Oil
* Basil Oil
* Bay Leaf, Oil and Sweet Oil
* Beeswax White
* Beet Juice Concentrate
* Benzaldehyde
* Benzaldehyde Glyceryl Acetal
* Benzoic Acid, Benzoin
* Benzoin Resin
* Benzophenone
* Benzyl Alcohol
* Benzyl Benzoate
* Benzyl Butyrate
* Benzyl Cinnamate
* Benzyl Propionate
* Benzyl Salicylate
* Bergamot Oil
* Bisabolene
* Black Currant Buds Absolute
* Borneol
* Bornyl Acetate
* Buchu Leaf Oil
* 1,3-Butanediol
* 2,3-Butanedione
* 1-Butanol
* 2-Butanone
* 4(2-Butenylidene)-3,5,5-Trimethyl-2-Cyclohexen-1-One
* Butter, Butter Esters, and Butter Oil
* Butyl Acetate
* Butyl Butyrate
* Butyl Butyryl Lactate
* Butyl Isovalerate
* Butyl Phenylacetate
* Butyl Undecylenate
* 3-Butylidenephthalide
* Butyric Acid]
* Cadinene
* Caffeine
* Calcium Carbonate
* Camphene
* Cananga Oil
* Capsicum Oleoresin
* Caramel Color
* Caraway Oil
* Carbon Dioxide
* Cardamom Oleoresin, Extract, Seed Oil, and Powder
* Carob Bean and Extract
* beta-Carotene
* Carrot Oil
* Carvacrol
* 4-Carvomenthenol
* 1-Carvone
* beta-Caryophyllene
* beta-Caryophyllene Oxide
* Cascarilla Oil and Bark Extract
* Cassia Bark Oil
* Cassie Absolute and Oil
* Castoreum Extract, Tincture and Absolute
* Cedar Leaf Oil
* Cedarwood Oil Terpenes and Virginiana
* Cedrol
* Celery Seed Extract, Solid, Oil, And Oleoresin
* Cellulose Fiber
* Chamomile Flower Oil And Extract
* Chicory Extract
* Chocolate
* Cinnamaldehyde
* Cinnamic Acid
* Cinnamon Leaf Oil, Bark Oil, and Extract
* Cinnamyl Acetate
* Cinnamyl Alcohol
* Cinnamyl Cinnamate
* Cinnamyl Isovalerate
* Cinnamyl Propionate
* Citral
* Citric Acid
* Citronella Oil
* dl-Citronellol
* Citronellyl Butyrate
* itronellyl Isobutyrate
* Civet Absolute
* Clary Oil
* Clover Tops, Red Solid Extract
* Cocoa
* Cocoa Shells, Extract, Distillate And Powder
* Coconut Oil
* Coffee
* Cognac White and Green Oil
* Copaiba Oil
* Coriander Extract and Oil
* Corn Oil
* Corn Silk
* Costus Root Oil
* Cubeb Oil
* Cuminaldehyde
* para-Cymene
* 1-Cysteine
D-M
* Dandelion Root Solid Extract
* Davana Oil
* 2-trans, 4-trans-Decadienal
* delta-Decalactone
* gamma-Decalactone
* Decanal
* Decanoic Acid
* 1-Decanol
* 2-Decenal
* Dehydromenthofurolactone
* Diethyl Malonate
* Diethyl Sebacate
* 2,3-Diethylpyrazine
* Dihydro Anethole
* 5,7-Dihydro-2-Methylthieno(3,4-D) Pyrimidine
* Dill Seed Oil and Extract
* meta-Dimethoxybenzene
* para-Dimethoxybenzene
* 2,6-Dimethoxyphenol
* Dimethyl Succinate
* 3,4-Dimethyl-1,2 Cyclopentanedione
* 3,5- Dimethyl-1,2-Cyclopentanedione
* 3,7-Dimethyl-1,3,6-Octatriene
* 4,5-Dimethyl-3-Hydroxy-2,5-Dihydrofuran-2-One
* 6,10-Dimethyl-5,9-Undecadien-2-One
* 3,7-Dimethyl-6-Octenoic Acid
* 2,4 Dimethylacetophenone
* alpha,para-Dimethylbenzyl Alcohol
* alpha,alpha-Dimethylphenethyl Acetate
* alpha,alpha Dimethylphenethyl Butyrate
* 2,3-Dimethylpyrazine
* 2,5-Dimethylpyrazine
* 2,6-Dimethylpyrazine
* Dimethyltetrahydrobenzofuranone
* delta-Dodecalactone
* gamma-Dodecalactone
* para-Ethoxybenzaldehyde
* Ethyl 10-Undecenoate
* Ethyl 2-Methylbutyrate
* Ethyl Acetate
* Ethyl Acetoacetate
* Ethyl Alcohol
* Ethyl Benzoate
* Ethyl Butyrate
* Ethyl Cinnamate
* Ethyl Decanoate
* Ethyl Fenchol
* Ethyl Furoate
* Ethyl Heptanoate
* Ethyl Hexanoate
* Ethyl Isovalerate
* Ethyl Lactate
* Ethyl Laurate
* Ethyl Levulinate
* Ethyl Maltol
* Ethyl Methyl Phenylglycidate
* Ethyl Myristate
* Ethyl Nonanoate
* Ethyl Octadecanoate
* Ethyl Octanoate
* Ethyl Oleate
* Ethyl Palmitate
* Ethyl Phenylacetate
* Ethyl Propionate
* Ethyl Salicylate
* Ethyl trans-2-Butenoate
* Ethyl Valerate
* Ethyl Vanillin
* 2-Ethyl (or Methyl)-(3,5 and 6)-Methoxypyrazine
* 2-Ethyl-1-Hexanol, 3-Ethyl -2 -Hydroxy-2-Cyclopenten-1-One
* 2-Ethyl-3, (5 or 6)-Dimethylpyrazine
* 5-Ethyl-3-Hydroxy-4-Methyl-2(5H)-Furanone
* 2-Ethyl-3-Methylpyrazine
* 4-Ethylbenzaldehyde
* 4-Ethylguaiacol
* para-Ethylphenol
* 3-Ethylpyridine
* Eucalyptol
* Farnesol
* D-Fenchone
* Fennel Sweet Oil
* Fenugreek, Extract, Resin, and Absolute
* Fig Juice Concentrate
* Food Starch Modified
* Furfuryl Mercaptan
* 4-(2-Furyl)-3-Buten-2-One
* Galbanum Oil
* Genet Absolute
* Gentian Root Extract
* Geraniol
* Geranium Rose Oil
* Geranyl Acetate
* Geranyl Butyrate
* Geranyl Formate
* Geranyl Isovalerate
* Geranyl Phenylacetate
* Ginger Oil and Oleoresin
* 1-Glutamic Acid
* 1-Glutamine
* Glycerol
* Glycyrrhizin Ammoniated
* Grape Juice Concentrate
* Guaiac Wood Oil
* Guaiacol
* Guar Gum
* 2,4-Heptadienal
* gamma-Heptalactone
* Heptanoic Acid
* 2-Heptanone
* 3-Hepten-2-One
* 2-Hepten-4-One
* 4-Heptenal
* trans -2-Heptenal
* Heptyl Acetate
* omega-6-Hexadecenlactone
* gamma-Hexalactone
* Hexanal
* Hexanoic Acid
* 2-Hexen-1-Ol
* 3-Hexen-1-Ol
* cis-3-Hexen-1-Yl Acetate
* 2-Hexenal
* 3-Hexenoic Acid
* trans-2-Hexenoic Acid
* cis-3-Hexenyl Formate
* Hexyl 2-Methylbutyrate
* Hexyl Acetate
* Hexyl Alcohol
* Hexyl Phenylacetate
* 1-Histidine
* Honey
* Hops Oil
* Hydrolyzed Milk Solids
* Hydrolyzed Plant Proteins
* 5-Hydroxy-2,4-Decadienoic Acid delta- Lactone
* 4-Hydroxy-2,5-Dimethyl-3(2H)-Furanone
* 2-Hydroxy-3,5,5-Trimethyl-2-Cyclohexen-1-One
* 4-Hydroxy -3-Pentenoic Acid Lactone
* 2-Hydroxy-4-Methylbenzaldehyde
* 4-Hydroxybutanoic Acid Lactone
* Hydroxycitronellal
* 6-Hydroxydihydrotheaspirane
* 4-(para-Hydroxyphenyl)-2-Butanone
* Hyssop Oil
* Immortelle Absolute and Extract
* alpha-Ionone
* beta-Ionone
* alpha-Irone
* Isoamyl Acetate
* Isoamyl Benzoate
* Isoamyl Butyrate
* Isoamyl Cinnamate
* Isoamyl Formate, Isoamyl Hexanoate
* Isoamyl Isovalerate
* Isoamyl Octanoate
* Isoamyl Phenylacetate
* Isobornyl Acetate
* Isobutyl Acetate
* Isobutyl Alcohol
* Isobutyl Cinnamate
* Isobutyl Phenylacetate
* Isobutyl Salicylate
* 2-Isobutyl-3-Methoxypyrazine
* alpha-Isobutylphenethyl Alcohol
* Isobutyraldehyde
* Isobutyric Acid
* d,l-Isoleucine
* alpha-Isomethylionone
* 2-Isopropylphenol
* Isovaleric Acid
* Jasmine Absolute, Concrete and Oil
* Kola Nut Extract
* Labdanum Absolute and Oleoresin
* Lactic Acid
* Lauric Acid
* Lauric Aldehyde
* Lavandin Oil
* Lavender Oil
* Lemon Oil and Extract
* Lemongrass Oil
* 1-Leucine
* Levulinic Acid
* Licorice Root, Fluid, Extract and Powder
* Lime Oil
* Linalool
* Linalool Oxide
* Linalyl Acetate
* Linden Flowers
* Lovage Oil And Extract
* 1-Lysine]
* Mace Powder, Extract and Oil
* Magnesium Carbonate
* Malic Acid
* Malt and Malt Extract
* Maltodextrin
* Maltol
* Maltyl Isobutyrate
* Mandarin Oil
* Maple Syrup and Concentrate
* Mate Leaf, Absolute and Oil
* para-Mentha-8-Thiol-3-One
* Menthol
* Menthone
* Menthyl Acetate
* dl-Methionine
* Methoprene
* 2-Methoxy-4-Methylphenol
* 2-Methoxy-4-Vinylphenol
* para-Methoxybenzaldehyde
* 1-(para-Methoxyphenyl)-1-Penten-3-One
* 4-(para-Methoxyphenyl)-2-Butanone
* 1-(para-Methoxyphenyl)-2-Propanone
* Methoxypyrazine
* Methyl 2-Furoate
* Methyl 2-Octynoate
* Methyl 2-Pyrrolyl Ketone
* Methyl Anisate
* Methyl Anthranilate
* Methyl Benzoate
* Methyl Cinnamate
* Methyl Dihydrojasmonate
* Methyl Ester of Rosin, Partially Hydrogenated
* Methyl Isovalerate
* Methyl Linoleate (48%)
* Methyl Linolenate (52%) Mixture
* Methyl Naphthyl Ketone
* Methyl Nicotinate
* Methyl Phenylacetate
* Methyl Salicylate
* Methyl Sulfide
* 3-Methyl-1-Cyclopentadecanone
* 4-Methyl-1-Phenyl-2-Pentanone
* 5-Methyl-2-Phenyl-2-Hexenal
* 5-Methyl-2-Thiophenecarboxaldehyde
* 6-Methyl-3,-5-Heptadien-2-One
* 2-Methyl-3-(para-Isopropylphenyl) Propionaldehyde
* 5-Methyl-3-Hexen-2-One
* 1-Methyl-3Methoxy-4-Isopropylbenzene
* 4-Methyl-3-Pentene-2-One
* 2-Methyl-4-Phenylbutyraldehyde
* 6-Methyl-5-Hepten-2-One
* 4-Methyl-5-Thiazoleethanol
* 4-Methyl-5-Vinylthiazole
M-Z
* Methyl-alpha-Ionone
* Methyl-trans-2-Butenoic Acid
* 4-Methylacetophenone
* para-Methylanisole
* alpha-Methylbenzyl Acetate
* alpha-Methylbenzyl Alcohol
* 2-Methylbutyraldehyde
* 3-Methylbutyraldehyde
* 2-Methylbutyric Acid
* alpha-Methylcinnamaldehyde
* Methylcyclopentenolone
* 2-Methylheptanoic Acid
* 2-Methylhexanoic Acid
* 3-Methylpentanoic Acid
* 4-Methylpentanoic Acid
* 2-Methylpyrazine
* 5-Methylquinoxaline
* 2-Methyltetrahydrofuran-3-One
* (Methylthio)Methylpyrazine (Mixture Of Isomers)
* 3-Methylthiopropionaldehyde
* Methyl 3-Methylthiopropionate
* 2-Methylvaleric Acid
* Mimosa Absolute and Extract
* Molasses Extract and Tincture
* Mountain Maple Solid Extract
* Mullein Flowers
* Myristaldehyde
* Myristic Acid
* Myrrh Oil
* beta-Napthyl Ethyl Ether
* Nerol
* Neroli Bigarde Oil
* Nerolidol
* Nona-2-trans,6-cis-Dienal
* 2,6-Nonadien-1-Ol
* gamma-Nonalactone
* Nonanal
* Nonanoic Acid
* Nonanone
* trans-2-Nonen-1-Ol
* 2-Nonenal
* Nonyl Acetate
* Nutmeg Powder and Oil
* Oak Chips Extract and Oil
* Oak Moss Absolute
* 9,12-Octadecadienoic Acid (48%) And 9,12,15-Octadecatrienoic Acid (52%)
* delta-Octalactone
* gamma-Octalactone
* Octanal
* Octanoic Acid
* 1-Octanol
* 2-Octanone
* 3-Octen-2-One
* 1-Octen-3-Ol
* 1-Octen-3-Yl Acetate
* 2-Octenal
* Octyl Isobutyrate
* Oleic Acid
* Olibanum Oil
* Opoponax Oil And Gum
* Orange Blossoms Water, Absolute, and Leaf Absolute
* Orange Oil and Extract
* Origanum Oil
* Orris Concrete Oil and Root Extract
* Palmarosa Oil
* Palmitic Acid
* Parsley Seed Oil
* Patchouli Oil
* omega-Pentadecalactone
* 2,3-Pentanedione
* 2-Pentanone
* 4-Pentenoic Acid
* 2-Pentylpyridine
* Pepper Oil, Black And White
* Peppermint Oil
* Peruvian (Bois De Rose) Oil
* Petitgrain Absolute, Mandarin Oil and Terpeneless Oil
* alpha-Phellandrene
* 2-Phenenthyl Acetate
* Phenenthyl Alcohol
* Phenethyl Butyrate
* Phenethyl Cinnamate
* Phenethyl Isobutyrate
* Phenethyl Isovalerate
* Phenethyl Phenylacetate
* Phenethyl Salicylate
* 1-Phenyl-1-Propanol
* 3-Phenyl-1-Propanol
* 2-Phenyl-2-Butenal
* 4-Phenyl-3-Buten-2-Ol
* 4-Phenyl-3-Buten-2-One
* Phenylacetaldehyde
* Phenylacetic Acid
* 1-Phenylalanine
* 3-Phenylpropionaldehyde
* 3-Phenylpropionic Acid
* 3-Phenylpropyl Acetate
* 3-Phenylpropyl Cinnamate
* 2-(3-Phenylpropyl)Tetrahydrofuran
* Phosphoric Acid
* Pimenta Leaf Oil
* Pine Needle Oil, Pine Oil, Scotch
* Pineapple Juice Concentrate
* alpha-Pinene, beta-Pinene
* D-Piperitone
* Piperonal
* Pipsissewa Leaf Extract
* Plum Juice
* Potassium Sorbate
* 1-Proline
* Propenylguaethol
* Propionic Acid
* Propyl Acetate
* Propyl para-Hydroxybenzoate
* Propylene Glycol
* 3-Propylidenephthalide
* Prune Juice and Concentrate
* Pyridine
* Pyroligneous Acid And Extract
* Pyrrole
* Pyruvic Acid
* Raisin Juice Concentrate
* Rhodinol
* Rose Absolute and Oil
* Rosemary Oil
* Rum
* Rum Ether
* Rye Extract
* Sage, Sage Oil, and Sage Oleoresin
* Salicylaldehyde
* Sandalwood Oil, Yellow
* Sclareolide
* Skatole
* Smoke Flavor
* Snakeroot Oil
* Sodium Acetate
* Sodium Benzoate
* Sodium Bicarbonate
* Sodium Carbonate
* Sodium Chloride
* Sodium Citrate
* Sodium Hydroxide
* Solanone
* Spearmint Oil
* Styrax Extract, Gum and Oil
* Sucrose Octaacetate
* Sugar Alcohols
* Sugars
* Tagetes Oil
* Tannic Acid
* Tartaric Acid
* Tea Leaf and Absolute
* alpha-Terpineol
* Terpinolene
* Terpinyl Acetate
* 5,6,7,8-Tetrahydroquinoxaline
* 1,5,5,9-Tetramethyl-13-Oxatricyclo(8.3.0.0(4,9))Tridecane
* 2,3,4,5, and 3,4,5,6-Tetramethylethyl-Cyclohexanone
* 2,3,5,6-Tetramethylpyrazine
* Thiamine Hydrochloride
* Thiazole
* 1-Threonine
* Thyme Oil, White and Red
* Thymol
* Tobacco Extracts
* Tochopherols (mixed)
* Tolu Balsam Gum and Extract
* Tolualdehydes
* para-Tolyl 3-Methylbutyrate
* para-Tolyl Acetaldehyde
* para-Tolyl Acetate
* para-Tolyl Isobutyrate
* para-Tolyl Phenylacetate
* Triacetin
* 2-Tridecanone
* 2-Tridecenal
* Triethyl Citrate
* 3,5,5-Trimethyl -1-Hexanol
* para,alpha,alpha-Trimethylbenzyl Alcohol
* 4-(2,6,6-Trimethylcyclohex-1-Enyl)But-2-En-4-One
* 2,6,6-Trimethylcyclohex-2-Ene-1,4-Dione
* 2,6,6-Trimethylcyclohexa-1,3-Dienyl Methan
* 4-(2,6,6-Trimethylcyclohexa-1,3-Dienyl)But-2-En-4-One
* 2,2,6-Trimethylcyclohexanone
* 2,3,5-Trimethylpyrazine
* 1-Tyrosine
* delta-Undercalactone
* gamma-Undecalactone
* Undecanal
* 2-Undecanone, 1
* 0-Undecenal
* Urea
* Valencene
* Valeraldehyde
* Valerian Root Extract, Oil and Powder
* Valeric Acid
* gamma-Valerolactone
* Valine
* Vanilla Extract And Oleoresin
* Vanillin
* Veratraldehyde
* Vetiver Oil
* Vinegar
* Violet Leaf Absolute
* Walnut Hull Extract
* Water
* Wheat Extract And Flour
* Wild Cherry Bark Extract
* Wine and Wine Sherry
* Xanthan Gum
* 3,4-Xylenol
* Yeast

[Hanse]

59. The major carcinogens found in cigarette smoke:

acrolein
polycyclic aromatic hydrocarbons
N-nitrosamines
carbon monoxide

Also found in marijuana smoke, as they're formed from incomplete combustion.

[dysfunctional press]

61. so- benzene is no longer a major carcinogen...since when?

huh...

[Hanse]

64. Uh, since it's not one of the major components of cigarette smoke.

And while it still undergoes the same basic mechanism of carcinogenesis, epoxidation by cytochrome p450 and subsequent electrophilic adduction to DNA and proteins, it's not as prone to as the other aromatic hydrocarbons.

Duh.

[dysfunctional press]

65. tsna's then...?

being "tobacco specific", by definition- they aren't found in pot.

Tobacco-specific N-nitrosamines (TSNAs) are known to be some of the most potent carcinogens present in smokeless tobacco, snuff and tobacco smoke.

TSNAs consist of four chemical compounds:

* N-nitrosonornicotine (NNN)
* 4-methyl-N-nitrosamino-1-(3-pyridyl)-1-butanone (NNK)
* N-nitrosoanatabine (NAT)
* N-nitrosoanabasine (NAB)

Two of these chemical compounds, NNN and NNK, have been classifed as Group 2B carcinogens.

[dysfunctional press]

66. btw- you said major carcinogens, not major components.

[Hanse]

69. Benzene is neither a major component nor major carcinogen.

Hell, despite its widespread presence in chemistry for two hundred years, it's only recently, grudgingly been recognized as a carcinogen.

The other, more common, and more carcinogenic compounds in cigarettes, acrolein, for example, make benzene look like marshmallow by comparison.

"btw- you said major carcinogens, not major components."

I'm sorry, I didn't think I was making this complicated. The major chemical species in cigarette smoke which are responsible for carcinogenesis in smokers. The major components of cigarette smoke are carbon dioxide and water, neither of which cause cancer.

Edited for clarity.

[ShortnFiery]

48. Just perhaps those folks suffering from chronic pain or terminal cancer don't truly care about LONG

TERM effects from extraneous chemicals? Besides if you legalize marijuana, we can ensure it's quality/purity.

[usregimechange]

49. Good point, and docs should be able to consider cost benefits in such cases

[ShortnFiery]

50. Thank-you. If I was terminally ill, I would not wish for my family to go into increasing debt

in order to afford pain medications that would make me "comfortable." There are many things to consider - cost to one's family has to fit into the mix on the higher end of priorities. Especially since we pay so damn much for our medications, co-payments or not.

[dysfunctional press]

63. good pain meds don't have to be expensive.

methadone works well for me, for less than 40 bucks a month. i had been on oxycontin, which is much more expensive- but when i lost my insurance, the dr. switched me over, and it's just as effective.

[Romulox]

80. Another "faith based" prohibitionist argument.

"If cannabinoids can kill tumor cells, it may not then follow that they are healthy for regular noncancerous cells. "

This is not science: "it may not follow...."

[Bluenorthwest]

81. If it does not benefit you to smoke it

then don't. You could ingest it in countless smoke free ways, or not at all. Your assumption that others can not read the ariticle is absurd, as is your assumption that smoking is the only way to use marijuana.

[cbc5g]

82. Good call...we need stronger weed so we smoke less

I have crohn's disease so i'm not stopping smoking just cause it may kill some healthy brain cells which has never been proven. But if you are worried about my health you could get me a volcano vaporizer...they are just too damn expensive especially with weed prices the way they are.