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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsLA doctor seeing success with hydroxychloroquine to treat COVID-19
Hydroxychloroquine has been touted as a possible treatment for COVID-19 by President Trump among others, but it remains controversial as some experts believe it is unproven and may not be effective.
The drug has long been used for treatment of malaria and conditions such as lupus and arthritis but is not technically approved by the FDA for COVID-19. The agency, however, is encouraging trials and has provided limited emergency authorization for its use to treat COVID-19 patients.
Dr. Anthony Cardillo said he has seen very promising results when prescribing hydroxychloroquine in combination with zinc for the most severely-ill COVID-19 patients.
"Every patient I've prescribed it to has been very, very ill and within 8 to 12 hours, they were basically symptom-free," Cardillo told Eyewitness News. "So clinically I am seeing a resolution."
Cardillo is the CEO of Mend Urgent Care, which has locations in Sherman Oaks, Van Nuys and Burbank.
He said he has found it only works if combined with zinc. The drug, he said, opens a channel for the zinc to enter the cell and block virus replication.
He added that the drug should not be prescribed for those who are presenting only mild symptoms, as there are concerns about shortages for patients with other conditions who need to take the drug on a regular basis.
"We have to be cautious and mindful that we don't prescribe it for patients who have COVID who are well," Cardillo said. "It should be reserved for people who are really sick, in the hospital or at home very sick, who need that medication. Otherwise we're going to blow through our supply for patients that take it regularly for other disease processes."
https://abc7.com/coronavirus-drug-covid-19-malaria-hydroxychloroquine/6079864/
The Key is the Hydroxychloroquine must be taken in COMBINATION with Zinc, according to this Physician.
Azathoth
(4,607 posts)I'm all for a miracle drug, but this sets off my bullshit detector. Even most antibiotics don't cure moderate bacterial bronchitis and pneumonia in "8 to 12 hours".
This guy sounds like a clown.
exboyfil
(17,862 posts)Or a charlatan.
Basic LA
(2,047 posts)...how can that be?
Docreed2003
(16,858 posts)EndlessWire
(6,508 posts)but, as an example of medicine that can wipe out inflamation in short order, prednisone is something of a miracle drug. Of course you can't take it long term, but it can set you right in 8-12 hours.
notdarkyet
(2,226 posts)Tucker08087
(621 posts)It has a lot of bad side-effects, but if you use it for a few weeks, its like a miracle drug.
Tech
(1,770 posts)has a lot of side effects. I think it is what they are cautioning, a lot of different results with side effects. I am leery of the doctor as it is based on what he says, I would like to see proof.
brush
(53,764 posts)Mosby
(16,297 posts)woodsprite
(11,910 posts)exboyfil
(17,862 posts)I would think that there would be a website for doctors to report findings prior to peer review.
A non-double blind study without a control group?
For God's sake can we get some reporters with at least some level of statistics knowledge? These are basic questions. He has drawn conclusions about the mechanism without forming any sort of hypothesis and testing it.
Azathoth
(4,607 posts)Not take two vitamins and an off-label drug and call me in the morning.
The guy's mischaracterizing the severity of his patients' illnesses, presenting unverifiable anecdotes as evidence, and pulling an explanation for it all out of his ass.
LovingA2andMI
(7,006 posts)Once that production is stopped, the body will return to wellness.
Azathoth
(4,607 posts)It's a simple statement that glosses over a ton of details.
Hydroxychloroquine is not a new drug. It's been investigated as an antirviral before. The most that can be said about it right now is that it *might* reduce the duration of symptoms of *some* people with mild illness.
LovingA2andMI
(7,006 posts)In COMBINATION with some other drug or in this case vitamin like Zinc.
Mariana
(14,854 posts)uponit7771
(90,335 posts)... it or the doctors would be authorized to give it.
11,000 people dead and no one can decide the efficacy of this drug combo on the terminal yet?
Yeah, sounds a little iffy
LovingA2andMI
(7,006 posts)In other words, the Viral Load of RNA Cells cannot be in overload in the patient's body. If that's the case --- the timing of when the combination is given to a patient is of optimal importance.
dansolo
(5,376 posts)Which means that the viral load is already high.
uponit7771
(90,335 posts)... just the sake of efficacy on the terminally ill?
We'll see
LovingA2andMI
(7,006 posts)Quickly!
mzmolly
(50,985 posts)true.
thucythucy
(8,043 posts)even if they "recover" will often be left with permanent damage to their lungs.
So either the people he's treating aren't among the most ill (in which case they might well have recovered even without the drug--hence the need for double blind studies) or he may be overplaying it when he says "completely recovered" or "cured."
I bet there are now very many desperate people going to be knocking at this doctor's door. Let's hope then that this does help the people who need it.
Drahthaardogs
(6,843 posts)No all studies coming out are NOT going to rise to that level.
However, I find being cured in 8 hours bullshit.
Cholorquine has a half life of 20 days for terminal elimination. This would be one dose and you are cured.
ProfessorGAC
(64,990 posts)Good info, too.
msongs
(67,394 posts)LovingA2andMI
(7,006 posts)And before anyone goes there -- We Know Her and Her Spouse and GLAD she is doing well after losing Former State Representative and Friend Isaac Robinson.....
Detroit rep says hydroxychloroquine, Trump helped save her life amid COVID-19 fight
State Rep. Karen Whitsett, who learned Monday she has tested positive for COVID-19, said she started taking hydroxychloroquine on March 31, prescribed by her doctor, after both she and her husband sought treatment for a range of symptoms on March 18.
"It was less than two hours" before she started to feel relief, said Whitsett, who had experienced shortness of breath, swollen lymph nodes, and what felt like a sinus infection. She is still experiencing headaches, she said.
Whitsett said she was familiar with "the wonders" of hydroxychloroquine from an earlier bout with Lyme disease, but does not believe she would have thought to ask for it, or her doctor would have prescribed it, had Trump not been touting it as a possible treatment for COVID-19.
Trump, at his daily coronavirus briefings, has repeatedly touted the drug in combination with the antibiotic azithromycin, despite criticism from health professionals that it is unproven and potentially dangerous. There have also been complaints that Trump's remarks have resulted in a shortage of the drug for those people who normally use it for its recommended purposes.
But Whitsett said Trump's comments helped in her case.
"It has a lot to do with the president ... bringing it up," Whitsett said. "He is the only person who has the power to make it a priority."
Asked whether she thinks Trump may have saved her life, Whitsett said: "Yes, I do," and "I do thank him for that."
Hydroxychloroquine is used to prevent and treat malaria and also used to treat lupus and rheumatoid arthritis, among other ailments.
Whitsett said she has been taking it in combination with antibiotics."
https://www.freep.com/story/news/local/michigan/detroit/2020/04/06/democrat-karen-whitsett-coronavirus-hydroxychloroquine-trump/2955430001/
Grasswire2
(13,565 posts)LovingA2andMI
(7,006 posts)Does nothing against a Virus.
rockfordfile
(8,701 posts)"trump helped save her life"
LovingA2andMI
(7,006 posts)If the drug in a combination helped against a deadly virus --- it is what it is. More studies are needed but saving lives is more important that keeping a drug that in combination with Zinc or Antibiotics can Save Lives.
The New York City study will tell the tale.
Eyeball_Kid
(7,430 posts)then let's just call it that and leave open the possibility that it worked.
It does sound very unlikely, ESPECIALLY considering what the drug does inside a body. Opinions vary, but it's generally considered an immunosuppressant. So it's somewhat counterintuitive to consider it to be a drug that makes one IMMUNE from a virus. But maybe something happens to the drug when zinc is added. Who knows.
Midnight Writer
(21,739 posts)who smoked three packs a day and lived to be ninety.
Just because an outcome is preceded by an treatment, doesn't mean the treatment caused the outcome.
If a person were to dream of their deceased Mother, and then got better, might they not attribute their recovery to their Mother watching over them?
I may.
But it doesn't make it true.
I hope this is an effective treatment, but it needs evaluation.
Cha
(297,123 posts)talking about it... But if he had Not claimed it was a "Democratic Hoax" for 70 days while he played golf and staged rallies many people would Not be dead.. and businesses and jobs Lost. some restaurants forever.
He is responsible for that.
standingtall
(2,785 posts)She doesn't look that old to me at least 80% of people recover from it. People even recover without treatment. So chances are her life wasn't in danger to begin with. She had taking the drug before for Lyme disease. This could simply be a case of placebo effect.
Girard442
(6,067 posts)Imagine the doctors try to replicate Cardillo's results and can't. They announce that his treatment has been tested and has been found to be worthless. Trump announces to his base that the evil medical establishment is suppressing a known cure and he's not responsible for all those dead people who could have been cured. Not his fault.
LovingA2andMI
(7,006 posts)If hydroxychloroquine with a combination of Zinc and/or Antibiotics -- Trump will take credit -- however the REAL CREDIT goes the China Doctors who tested hydroxychloroquine in the first place.
Girard442
(6,067 posts)I'm more worried about a scam that kills even more people and sets the survivors against each other.
LovingA2andMI
(7,006 posts)However, if the proof is there -then saving lives must trump literally everything else.
Girard442
(6,067 posts)sheshe2
(83,728 posts)Paid Cohen over a million dollars for access to Trump after the inauguration. He wanted to promote his drug.
Not sure where it was posted.
uponit7771
(90,335 posts)... come on you'd think this would have happened already.
Yavin4
(35,432 posts)We do not proscribe medicine based on what one or 100 or even 1000 doctors think, observe, or experience. We proscribe medicine based on clinical trials, double blind studies, etc.
Every day feels like we have to go back to school.
LovingA2andMI
(7,006 posts)If hydroxychloroquine works in combination with Zinc or Antibiotics in 100 patients and they don't die as a result -- saving lives is more important than providing Trump right or wrong. Period!
Girard442
(6,067 posts)Yavin4
(35,432 posts)You have to prove that the drug is more effective than doing nothing. You also have to account for different patients at different stages of the drug.
You don't want to open up the Wild West and have people taking all manner of drugs as some sort of Hail Mary.
dawg day
(7,947 posts)It's not a great trade if the patient ends up impaired by the drug treatment. That's why drug trials have protocols, and disclosures so that patients know the risks.
rockfordfile
(8,701 posts)People are getting infected because of trump's corruption and lies. The republican governors corrupt handling of the outbreak in their states.
LovingA2andMI
(7,006 posts)Very true.
Laffy Kat
(16,376 posts)Due to severe side-effects. So far, though, this is the only citation I can find:
https://www.newsweek.com/swedish-hospitals-chloroquine-covid-19-side-effects-1496368
LovingA2andMI
(7,006 posts)Even the Doctor cited above says hydroxychloroquine by itself was NOT effective.
Laffy Kat
(16,376 posts)There's a lot about this that sounds off to me, although I'm trying to keep an open mind.
at140
(6,110 posts)I heard the doc say.
LovingA2andMI
(7,006 posts)If one unlocks the key and allows for positive DNA nuclei to enter the hole to combat the Virus load, the Virus is either suppressed or disappear.
In the case of HIV - the Combination Drug Cocktail suppresses HIV from becoming full blown AIDS.
Kathy M
(1,242 posts)edit to add I remember reading this combo being used in France also and I think couple other countries
Rstrstx
(1,399 posts)Hydroxychloroquine is better tolerated. Chinese doctors are apparently going with chloroquine, perhaps it's easier to get there?
Hoyt
(54,770 posts)similar drugs.
More than a few physicians think its better than nothing. Enough are prescribing it for some reason, to create fears of a shortage here and globally.
Tech
(1,770 posts)Hoyt
(54,770 posts)DeminPennswoods
(15,276 posts)for the patients who had covid19. Glad it worked for them and they recovered.
Also, I believe that China is doing controlled studies with hydroxychloroquine and a placebo.
LovingA2andMI
(7,006 posts)In China.
sfstaxprep
(9,998 posts)Boris Johnson will be all better by the morning. If there is the slightest chance this stuff works, you can be certain he's been given the full treatment.
LovingA2andMI
(7,006 posts)Is not too far gone -- then yes, probably
Kathy M
(1,242 posts)dansolo
(5,376 posts)He claims that it works on the sickest of his patients.
uponit7771
(90,335 posts)SidDithers
(44,228 posts)Anecdotal evidence of live experimentation without a control group.
Peachy.
sid
Girard442
(6,067 posts)spin
(17,493 posts)At my age and with my underlying conditions I am definitely a prime target for COVID-19.
Hydroxychloroquine has been around for a long time. It was approved for use in the U.S. in 1955. Its side effects are well known. If I was about to die and my doctor felt it was worth a try I would happy to give it a shot.
dchill
(38,465 posts)LovingA2andMI
(7,006 posts)Zinc is also found in many Health Food Stores. Going to order this Vitamin and adding it to my supplement list - tomorrow.
Hamlette
(15,411 posts)I've been taking it for about a month on the theory if it can stop a cold, maybe it will work on another virus. I'm nearly out and we've been looking for about 10 days.
Cold-eze is basically zinc if you can find that. We can't but are still looking.
at140
(6,110 posts)Hemp, flax, pumpkin or squash seeds,
red meat, cashews, peanuts, dark chocolate
LovingA2andMI
(7,006 posts)Will do.
dchill
(38,465 posts)Mike 03
(16,616 posts)at140
(6,110 posts)stillcool
(32,626 posts)Prescribing this, and I'm wondering if the patients give permission, and are aware that there is no evidence that the drug works, or is safe to use with COVID19. Or do they just give you any cocktail they want? Seems unethical to me, but I guess I'm missing something. If it works you would think the AMA would be all over it, long before a single doctor is profiled by ABC...if it turns out to be harmful ABC should be sued out of business.
LovingA2andMI
(7,006 posts)Going on in NYC and the FDA did open limited uses of hydroxychloroquine with COVID-19. This happened days ago.
Azathoth
(4,607 posts)Last edited Tue Apr 7, 2020, 10:28 AM - Edit history (1)
which is emerging as the current treatment guidelines.
They're using it because they've got nothing else, including drugs they think have a better chance of working but can't obtain, like remdesivir.
napi21
(45,806 posts)story with this Hydroxiechlor
. most said they experienced some mild improvement, but one lady said it almost killed her. She had only taken 1 dose/ I forget what she said happened to her, but she was admitted to the hospital and came very close to death and she was told it was her body's reaction to the drug.
It just bothers me that DT is touting this drug even though he has no medical training, hell, he's not even married to a medical professional. He should leave the drug recommendations to the experts!
LovingA2andMI
(7,006 posts)The studies must be done by Medical experts and not a man who never obtained a Ph.D.
at140
(6,110 posts)Democratic state lawmaker credits President Trump and hydroxychloroquine with saving her life!
Michigan State Rep. Karen Whitsett says her COVID-19 symptoms went away within just a couple hours of taking hydroxychloroquine.
LovingA2andMI
(7,006 posts)In Combination -- not alone.
at140
(6,110 posts)SlogginThroughIt
(1,977 posts)Was she tested? Did she have it? Does she have antibodies? Because if her symptoms went away with a zpack or something else I would say no shit sherlock!
at140
(6,110 posts)I am sure Google has all the information. I am just too busy here taking care of my stage-4 cancer wife and all the household chores.
greenjar_01
(6,477 posts)LovingA2andMI
(7,006 posts)of Drugs can suppress or eliminate a RNA Virus? Ever heard of the HIV - Virus DRUG COCKTAIL?
greenjar_01
(6,477 posts)Slurping up nonsense and spreading it around. Say combination again. It makes it sound more sciencey.
LovingA2andMI
(7,006 posts)With post 124. Interesting your take on things. Very....
greenjar_01
(6,477 posts)you read my post count. Real science-like. The "Newbie-bashing" also a nice touch. Always the sign of a clear thinker.
Good luck with your miracle cure, in any case. In combination, of course.
LovingA2andMI
(7,006 posts)It's not MY anything but continue with that so sad and tired line. This is a forum, we posted an article -- ACTUALLY TWO OF THEM that cited the combination. There are other studies being done right now in New York City. P.S. -- We approved NONE OF THEM. The FDA did just in case you needed the facts --- as it appears you did.
Chew on that and have a wonderful night.
onenote
(42,686 posts)He had double pneumonia. He was given last rites. But his condition stabilized and after a week in the hospital he was released. Yes he was a healthy 56 year old. And yes, no one can say for certain that the combination is what turned things around. But his doctors think it did in his case.
That doesn't make it a miracle cure for everyone. But it also doesn't mean it is ineffective or dangerous for everyone either.
Buckeye_Democrat
(14,853 posts)If it provides some relief, maybe its because this virus tricks the immune system into doing more damage to healthy cells? This drug suppresses the immune system.
This video delves into the immune system response to Covid-19:
LONG-TERM improvement from that drug? Who knows? Temporary relief doesnt necessarily mean that will happen, assuming the anecdotes of relief are even true.
LovingA2andMI
(7,006 posts)More studies will prove if this is an option however --something must counteract the bodies response allowing the RNA Cell Nuclei to reproduce SARS-COVID-19 cells in a quick mutation that can lead to death in some cases.
We will see!
Buckeye_Democrat
(14,853 posts)Unless its through some very unexpected process?
It MIGHT provide some relief by suppressing the immune system, though.
The part about the immune response starts around the 2-minute mark of that video.
Im NOT a virologist or medical doctor. Im just trying to think about it logically. And Im still very skeptical.
LovingA2andMI
(7,006 posts)Not by itself.
Ms. Toad
(34,060 posts)Zinc is "miracle drug" for my colds. I've always had month-long colds that turned into bronchitis more frequently than not. Until I discovered zinc. I tried it as an "it can't hurt" option (after researching to find out the possibility that it could hurt was pretty darn small. I was dumbfounded at how well it worked.
Since that time the only colds that have lasted longer tha 3 days have been the very few when I didn't have access to zinc within the first 24 hours - OR - when I stopped taking it too soon. Only a couple of each, since I never want to experience that again.
But many colds are coronaviruses - so it make sense that zinc might work for it, as well. I had seen the suggestion earlier, and planned to try it should I feel any symptoms that might be COVID 19.
So I wonder if it really is the combination - or if it is the zinc.
Or a placebo effect. Which I'm good with, as long as it works
OilemFirchen
(7,143 posts)When did he get the results? (n.b.: Our largest hospital (Level 1 Trauma) has only been able to test patients at intake for about a week.)
What was the severity of their illness?
Unless they were only mildly symptomatic (of something) why were they being treated at urgent care centers?
Where are their testimonials?
This woo will kill people. Shame on the local ABC station. And on the OP, who thinks that zinc is a "vitamin".
SMDH.
demmiblue
(36,838 posts)MFM008
(19,804 posts)To good to be true.
It is.
Blasphemer
(3,261 posts)There were reports coming out of China weeks ago about the hydroxychloroquine zinc combination. The problem, as already noted, is the lack of a rigorous study showing safety and efficacy.
Snake Plissken
(4,103 posts)This is what actually patients think of him
https://www.healthgrades.com/physician/dr-anthony-cardillo-x34qk
He runs very crooked operation in his urgent care locations! They charge you a visit and they charge your coverage, double charge! Ive been waiting for my refund as they promised me because they got paid by my sons coverage. To be exact, 4 months, no refund yet. And the mr doctor here, is not...Read More
Sep 21, 2019
Visited the ER with a high fever and flu. I am a renal transplant patient hence the need to go to ER. A person not in my condition would probably just need to go to urgent care. Was assigned this doctor who was so nonchalant about my case and simply said to me, you have the flu. When I told him...Read More
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Jan 21, 2020
jmg257
(11,996 posts)Fingers crossed!
at140
(6,110 posts)since 1955 when the drug was approved. Dr Oz further said, he can not find a single Lupus patient receiving HCQ treatment, which is the standard medicine for Lupus, is infected with covid-19. Thedoctor wants anyone in country who is on HCQ treatment for Lupus AND has tested covid-19 positive to call him immediately.
Thats not how science works.
https://www.thedailybeast.com/why-is-alleged-quack-dr-oz-giving-coronavirus-advice-on-the-today-show
The telegenic Oz might well be a talented thoracic surgeonbest known as the host of the popular syndicated daytime program The Dr. Oz Showbut he is hardly an ideal dispenser of medical advice for an increasingly anxious American public.
Hes just a quack, said physician and scientific researcher Henry I. Miller, one of Ozs more vocal critics in the medical community, but by no means unique in his condemnation of, among other transgressions, Ozs enthusiastic endorsements of phony weight-loss remedies, his bogus claims of dangerous levels of arsenic in childrens apple juice, and his willingness to provide a platform to the debunked assertion that genetically modified food causes cancer.
Hes been dishonest and he has been dispensing misinformation to millions now for years, said Miller, who in 2015 led an unsuccessful campaign to pressure Columbia Universitys College of Physicians and Surgeons to fire Oz from its faculty. I wouldnt trust any of his observations, and dont see how he would have responsible and valid views on coronavirus.
NBC News declined to comment on Ozs critics or his role on the Today show, where he is one of several paid physician-contributorsbut surely the most famous and camera-savvywhove been enlisted in recent days as on-air experts to address viewers coronavirus concerns.
at140
(6,110 posts)a snake oil salesman. But my wife is a fan of his show and watches every morning, which is how I happened to listen to his commentary re: Lupus patients on HCQ. Since he has a large national audience, I will follow with interest his findings on Lupus patients on HCQ treatment without a single one coming down with covid-19. We are all looking for a treatment which works with the covid-19 chaos. Personally I still believe you can avoid infection if you are careful to never touch face with unwashed hands. I have been to grocery stores every 4-6 days, the bank, cancer clinic with my wife, and still no symptoms of covid-19. But I am like a cat on a hot tin roof due to my age of 80 years young.
janterry
(4,429 posts)without a control group
we have no idea.
MineralMan
(146,284 posts)TV News stories are not results of clinical trials, and Urgent Care doctors are not treating serious cases of COVID-19.
I'm quite skeptical about this story, to be very frank.
Squinch
(50,941 posts)negative effect on all patients in the study?
It was here on DU, I believe.
struggle4progress
(118,273 posts)Doremus
(7,261 posts)Welcome to the new normal of self-preservation.