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Dennis Donovan

(18,770 posts)
Sat Apr 11, 2020, 01:04 PM Apr 2020

Prelim rslts: pts that got hydroxychlorquine did worse than pts who rec'd supportive treatment only

Mayan Gilboa @gilboa_mayan

Preliminary results that patients that got hydroxychlorquine actually did worse than patients that received supportive treatment only.
Like a bucket of cold ice




Mayan Gilboa @gilboa_mayan

This got a lot of attention
I received this earlier this morning through social media. I do not know how it was obtained.
I guess this is a study still under review and is not yet peer reviewed.


I thought it is important for other people to hear about this not because I think the conclusions are decisive, but because I think that it should be emphasized that when we give our patients meds that were not examined in good big RCT's we might be doing harm.

7:33 AM - Apr 11, 2020





19 replies = new reply since forum marked as read
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Prelim rslts: pts that got hydroxychlorquine did worse than pts who rec'd supportive treatment only (Original Post) Dennis Donovan Apr 2020 OP
Dr. Trump disagrees strongly dalton99a Apr 2020 #1
It's really too early to say... Wounded Bear Apr 2020 #2
You kidding aren't you? Did you read the same abstract I read Dream Girl Apr 2020 #6
In the original study, 26 were given the drug and six immediately left the study bluedye33139 Apr 2020 #3
The drug company as well as t-rump made lots of money tho . . . Iliyah Apr 2020 #4
I have to wonder about future lawsuits exboyfil Apr 2020 #10
And underscores the obscenity of Texas authorities using this in a nursing home FULL of pts. hlthe2b Apr 2020 #5
Is outrageous that science-denying politicians did this in my state. Mersky Apr 2020 #13
A President of the US should never have inserted himself into this situation exboyfil Apr 2020 #7
Almost everyone who knows anything relevant have been warning that this would be the outcome... RockRaven Apr 2020 #8
Are you telling me Trump was wrong? Shocking. shockey80 Apr 2020 #9
Damn, he wanted to keep this quiet, now the jig is totally up. lark Apr 2020 #11
The orange hemorrhoid's Dave in VA Apr 2020 #12
NE Journal of Medicine vs rump's gut feelings Cirque du So-What Apr 2020 #14
K&R for visibility. crickets Apr 2020 #15
In Texas we are giving this drug to nursing home patients Gothmog Apr 2020 #16
Can the families sue? Crunchy Frog Apr 2020 #19
What a surprise nt Azathoth Apr 2020 #17
The FAILING New England Journal of Medicine. Who care what they say!? Crunchy Frog Apr 2020 #18

Wounded Bear

(58,647 posts)
2. It's really too early to say...
Sat Apr 11, 2020, 01:07 PM
Apr 2020

so far, we have what amounts to anecdotal evidence so far. Not a lot of data from controlled tests.

Says right on it: "Preliminary"

 

Dream Girl

(5,111 posts)
6. You kidding aren't you? Did you read the same abstract I read
Sat Apr 11, 2020, 01:22 PM
Apr 2020

The methodology appears solid and results seems incontrovertible
Eetbble

bluedye33139

(1,474 posts)
3. In the original study, 26 were given the drug and six immediately left the study
Sat Apr 11, 2020, 01:10 PM
Apr 2020

One died, and three went straight to the ICU for heroic life-saving efforts.

The French gentleman then decided to use only the 20 remaining and surviving subjects for his statistics, and by excluding the six people who had dramatic negative reactions, he fabricated his positive results.

It was an astonishing misuse of data. I'm still in shock that people read that study and concluded that the drug would confer immunity to the virus and would cure the virus in anyone it was given to. Six of them had horrifying reactions, six out of 26, and that was simply ignored.

exboyfil

(17,862 posts)
10. I have to wonder about future lawsuits
Sat Apr 11, 2020, 01:43 PM
Apr 2020

If he has a demonstrated equity position in the company. At least employees and their companies can be held liable for their statements regarding their products or those of their competitors. Given he is also President, so presumably having access to the best available information, he has the highest burden to be truthful and not speculate.

hlthe2b

(102,226 posts)
5. And underscores the obscenity of Texas authorities using this in a nursing home FULL of pts.
Sat Apr 11, 2020, 01:13 PM
Apr 2020

with contraindications for such usage. Old people are not mere guinea pigs for such experimentation.

Mersky

(4,980 posts)
13. Is outrageous that science-denying politicians did this in my state.
Sat Apr 11, 2020, 01:52 PM
Apr 2020

Am so tired of the republicans in the state’s government mucking about with their zealotry and abuse - every Texan should be ashamed of abbott’s interjection into the testing of this drug in an effort to please hair furher.

I’ve been meaning to find evidence of any ethics review process for what they pushed at that nursing home in Texas City. Makes me livid just questioning whether they were able to give consent or not, and whether it’s a medically appropriate population to test to begin with.

Gov abbott is a miserably mean-spirited man undeserving of the office he holds and wholly unqualified to direct medical experimentation under any circumstance.

He should be concerned with tests, testing, and then testing some more, obtaining PPE (Texas has companies that should already be manufacturing materials for such - like an alternative to koch industries’ Dacron/synthetic fiber used in the nasopharyngeal swabs), and maintaining social distancing measures until public health experts have solid numbers for when it is safe to loosen restrictions.

exboyfil

(17,862 posts)
7. A President of the US should never have inserted himself into this situation
Sat Apr 11, 2020, 01:40 PM
Apr 2020

Irrespective of how the drug did or did not work.

This President's approach is closer to Idiocracy than I hoped we ever come. The fact that the public doesn't understand it, and the press doesn't seem willing to educate them is a sad commentary on our country.

RockRaven

(14,959 posts)
8. Almost everyone who knows anything relevant have been warning that this would be the outcome...
Sat Apr 11, 2020, 01:40 PM
Apr 2020

The "evidence" which started this rabbit trail was horse-shit to begin with.

FIRST. DO. NO. HARM.

lark

(23,093 posts)
11. Damn, he wanted to keep this quiet, now the jig is totally up.
Sat Apr 11, 2020, 01:45 PM
Apr 2020

Proven beyond a shadow of a doubt that he is killing us on purpose for his own profits.

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