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Yavin4

(35,437 posts)
Wed Apr 15, 2020, 10:58 PM Apr 2020

Emergency room doctor, near death with coronavirus, saved after experimental treatment

The immune system normally uses proteins called cytokines as weapons in fighting a disease. For unknown reasons in some COVID-19 patients, the immune system first fails to respond quickly enough and then floods the body with cytokines, destroying blood vessels and filling the lungs with fluid.

The doctors tried a drug called Actemra, which was designed to treat rheumatoid arthritis but also approved in 2017 to treat cytokine storms in cancer patients.




https://www.latimes.com/world-nation/story/2020-04-13/coworkers-save-coronavirus-doctor
14 replies = new reply since forum marked as read
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Emergency room doctor, near death with coronavirus, saved after experimental treatment (Original Post) Yavin4 Apr 2020 OP
Maybe good news. triron Apr 2020 #1
Hopefully. This is what we should be concentrating on. Yavin4 Apr 2020 #2
Yaaaaay! SheltieLover Apr 2020 #3
It was also used on another patient who also survived. CaliforniaPeggy Apr 2020 #4
Potentially very good news. K&R for visibility. crickets Apr 2020 #5
He never would have made it without the ECMO machine... blitzen Apr 2020 #6
Good, because hydroxychloroquine does not work. nt SunSeeker Apr 2020 #7
That is not true!!! cstanleytech Apr 2020 #8
LOL SunSeeker Apr 2020 #9
And if you are in a position to order thirty MILLION of those piles for the public stockpile, at niyad Apr 2020 #11
UNDERSTAND THE CYTOKINE STORM keithbvadu2 Apr 2020 #10
never SamBob Apr 2020 #12
+1, uponit7771 Apr 2020 #13
I'm helping with a vitamin c drmeow Apr 2020 #14

Yavin4

(35,437 posts)
2. Hopefully. This is what we should be concentrating on.
Wed Apr 15, 2020, 11:01 PM
Apr 2020

Finding a treatment that can save lives until we get a vaccine in place. Take out the lethality of the disease if you cannot cure it total.

CaliforniaPeggy

(149,588 posts)
4. It was also used on another patient who also survived.
Wed Apr 15, 2020, 11:08 PM
Apr 2020

It's great news, but it's only 2 patients.

A great many more folks will need to participate in a (preferably) double-blind study to see if it really works on a broad spectrum of the population.

Still, this is a very promising start.

blitzen

(4,572 posts)
6. He never would have made it without the ECMO machine...
Thu Apr 16, 2020, 12:30 AM
Apr 2020

and there are only a handful, at most, in each state.

This is not to say that the drug was not instrumental in his recovery. But in his case, without ECMO he would not have been alive by the time they decided to try the drug.

cstanleytech

(26,284 posts)
8. That is not true!!!
Thu Apr 16, 2020, 01:03 AM
Apr 2020

It works great if you are a snake oil salesman that owns shares in a company that makes it and to increase sales of it you claim it will cure people of whatever malady they have.

niyad

(113,265 posts)
11. And if you are in a position to order thirty MILLION of those piles for the public stockpile, at
Thu Apr 16, 2020, 01:44 AM
Apr 2020

taxpayer expense, to further enrich yourself.

keithbvadu2

(36,775 posts)
10. UNDERSTAND THE CYTOKINE STORM
Thu Apr 16, 2020, 01:17 AM
Apr 2020

You can actually be too healthy to survive coronavirus 0409

UNDERSTAND THE CYTOKINE STORM

This coronavirus can trigger "Cytokine release syndrome" (a cytokine storm) in persons with particularly healthy immune systems. COVID-19 is a disease that you actually have a better chance of surviving if your immune system is slightly compromised. The 1918 flu pandemic (The Spanish Flu) killed between 50 and 100 million people, many of whom were young and healthy. Evidently, the virus triggers the body's immune system and keeps triggering it, non-stop and relentlessly, until the infected person is killed by their own, super-strong immune system. That is the essence of a cytokine storm, and it's why many young, healthy people are likely to be struck down by this disease.

https://www.democraticunderground.com/100213100840

https://www.democraticunderground.com/10142466698

https://en.wikipedia.org/wiki/Cytokine_release_syndrome

SamBob

(61 posts)
12. never
Thu Apr 16, 2020, 02:01 AM
Apr 2020

would have thought that having a somewhat compromised immune system might actually help a person get over the virus.
I truly hope that is the case.
Maybe because they compromised immune system has been through so much in it's time??

drmeow

(5,017 posts)
14. I'm helping with a vitamin c
Thu Apr 16, 2020, 10:18 AM
Apr 2020

Study at my hospital - my PI was probably consulted for this treatment!

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