Welcome to DU!
The truly grassroots left-of-center political community where regular people, not algorithms, drive the discussions and set the standards.
Join the community:
Create a free account
Support DU (and get rid of ads!):
Become a Star Member
Latest Breaking News
General Discussion
The DU Lounge
All Forums
Issue Forums
Culture Forums
Alliance Forums
Region Forums
Support Forums
Help & Search
Brazilian chloroquine study halted after high dose proved lethal for some patients
Source: The Guardian
Brazilian chloroquine study halted after high dose proved lethal for some patients
Concerns grow as the journal Nature raises alarm on serious heart risks associated with Covid-19 patients taking the drugs
Jessica Glenza
@JessicaGlenza
Fri 24 Apr 2020 20.20 BST
Last modified on Sat 25 Apr 2020 02.32 BST
A Brazilian study investigating whether the anti-malaria drug chloroquine was effective in treating patients with Covid-19 was halted on safety concerns, after a high dose of the drug proved lethal for some patients.
Chloroquine, and a related drug, hydroxychloroquine, in combination with the antibiotic azithromycin, has been touted as a potential treatment for coronavirus by Donald Trump despite a lack of evidence.
The findings were published as a letter in the journal Nature raised alarm about serious heart risks associated with Covid-19 patients taking the drugs and the US Food and Drug Administration warned of serious heart complications.
Donald Trump has previously urged Americans to take hydroxychloroquine, although he has apparently backed away from the drug in recent days, and on Thursday even suggested that injections of disinfectant could cure Covid-19 – an idea that was swiftly refuted by experts, who warned the public “please don’t inject bleach”.
The Brazilian study, published in the Journal of the American Medical Association Network Open (Jama), was halted by a safety monitoring board before even one-quarter of the planned 440 patients were enrolled. Eighty-one patients with Covid-19 or suspected Covid-19 were given a daily regimen of chloroquine. The randomized clinical trial separated the patients into a high-dose and a low-dose group.
-snip-
Concerns grow as the journal Nature raises alarm on serious heart risks associated with Covid-19 patients taking the drugs
Jessica Glenza
@JessicaGlenza
Fri 24 Apr 2020 20.20 BST
Last modified on Sat 25 Apr 2020 02.32 BST
A Brazilian study investigating whether the anti-malaria drug chloroquine was effective in treating patients with Covid-19 was halted on safety concerns, after a high dose of the drug proved lethal for some patients.
Chloroquine, and a related drug, hydroxychloroquine, in combination with the antibiotic azithromycin, has been touted as a potential treatment for coronavirus by Donald Trump despite a lack of evidence.
The findings were published as a letter in the journal Nature raised alarm about serious heart risks associated with Covid-19 patients taking the drugs and the US Food and Drug Administration warned of serious heart complications.
Donald Trump has previously urged Americans to take hydroxychloroquine, although he has apparently backed away from the drug in recent days, and on Thursday even suggested that injections of disinfectant could cure Covid-19 – an idea that was swiftly refuted by experts, who warned the public “please don’t inject bleach”.
The Brazilian study, published in the Journal of the American Medical Association Network Open (Jama), was halted by a safety monitoring board before even one-quarter of the planned 440 patients were enrolled. Eighty-one patients with Covid-19 or suspected Covid-19 were given a daily regimen of chloroquine. The randomized clinical trial separated the patients into a high-dose and a low-dose group.
-snip-
Read more: https://www.theguardian.com/world/2020/apr/24/chloroquine-study-coronavirus-brazil
3 replies
= new reply since forum marked as read
= new reply since forum marked as read
