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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsBrazilian chloroquine study halted after high dose proved lethal for some patients
Source: The Guardian
Brazilian chloroquine study halted after high dose proved lethal for some patients
Concerns grow as the journal Nature raises alarm on serious heart risks associated with Covid-19 patients taking the drugs
Jessica Glenza
@JessicaGlenza
Fri 24 Apr 2020 20.20 BST
Last modified on Sat 25 Apr 2020 02.32 BST
A Brazilian study investigating whether the anti-malaria drug chloroquine was effective in treating patients with Covid-19 was halted on safety concerns, after a high dose of the drug proved lethal for some patients.
Chloroquine, and a related drug, hydroxychloroquine, in combination with the antibiotic azithromycin, has been touted as a potential treatment for coronavirus by Donald Trump despite a lack of evidence.
The findings were published as a letter in the journal Nature raised alarm about serious heart risks associated with Covid-19 patients taking the drugs and the US Food and Drug Administration warned of serious heart complications.
Donald Trump has previously urged Americans to take hydroxychloroquine, although he has apparently backed away from the drug in recent days, and on Thursday even suggested that injections of disinfectant could cure Covid-19 an idea that was swiftly refuted by experts, who warned the public please dont inject bleach.
The Brazilian study, published in the Journal of the American Medical Association Network Open (Jama), was halted by a safety monitoring board before even one-quarter of the planned 440 patients were enrolled. Eighty-one patients with Covid-19 or suspected Covid-19 were given a daily regimen of chloroquine. The randomized clinical trial separated the patients into a high-dose and a low-dose group.
-snip-
Concerns grow as the journal Nature raises alarm on serious heart risks associated with Covid-19 patients taking the drugs
Jessica Glenza
@JessicaGlenza
Fri 24 Apr 2020 20.20 BST
Last modified on Sat 25 Apr 2020 02.32 BST
A Brazilian study investigating whether the anti-malaria drug chloroquine was effective in treating patients with Covid-19 was halted on safety concerns, after a high dose of the drug proved lethal for some patients.
Chloroquine, and a related drug, hydroxychloroquine, in combination with the antibiotic azithromycin, has been touted as a potential treatment for coronavirus by Donald Trump despite a lack of evidence.
The findings were published as a letter in the journal Nature raised alarm about serious heart risks associated with Covid-19 patients taking the drugs and the US Food and Drug Administration warned of serious heart complications.
Donald Trump has previously urged Americans to take hydroxychloroquine, although he has apparently backed away from the drug in recent days, and on Thursday even suggested that injections of disinfectant could cure Covid-19 an idea that was swiftly refuted by experts, who warned the public please dont inject bleach.
The Brazilian study, published in the Journal of the American Medical Association Network Open (Jama), was halted by a safety monitoring board before even one-quarter of the planned 440 patients were enrolled. Eighty-one patients with Covid-19 or suspected Covid-19 were given a daily regimen of chloroquine. The randomized clinical trial separated the patients into a high-dose and a low-dose group.
-snip-
Read more: https://www.theguardian.com/world/2020/apr/24/chloroquine-study-coronavirus-brazil
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Brazilian chloroquine study halted after high dose proved lethal for some patients (Original Post)
Eugene
Apr 2020
OP
malaise
(268,664 posts)1. Oops!
Life was all they had to lose.
MiniMe
(21,708 posts)2. That is 2 countries outside of the US where tRump has killed people
France and Brazil
Cha
(296,774 posts)3. Good call.. Jesus!