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still_one

(92,190 posts)
Fri May 22, 2020, 08:35 AM May 2020

Antimalarial drug touted by President Trump is linked to increased risk of death in Covid Patients

"An analysis of 96,000 patients shows those treated with hydroxychloroquine were also more likely to suffer irregular heart rhythms

A study of 96,000 hospitalized coronavirus patients on six continents found that those who received an antimalarial drug promoted by President Trump as a “game changer” in the fight against the virus had a significantly higher risk of death compared with those who did not.
People treated with hydroxychloroquine, or the closely related drug chloroquine, were also more likely to develop a type of irregular heart rhythm, or arrhythmia, that can lead to sudden cardiac death, it concluded.


The study, published Friday in the medical journal the Lancet, is the largest analysis to date of the risks and benefits of treating covid-19 patients with antimalarial drugs. It is based on a retrospective analysis of medical records, not a controlled study in which patients are divided randomly into treatment groups — a method considered the gold standard of medicine. But the sheer size of the study was convincing to some scientists.

“It’s one thing not to have benefit, but this shows distinct harm,” said Eric Topol, a cardiologist and director of the Scripps Research Translational Institute. “If there was ever was hope for this drug, this is the death of it.”
David Maron, director of preventive cardiology at the Stanford University School of Medicine, said that “these findings provide absolutely no reason for optimism that these drugs might be useful in the prevention or treatment of covid-19.”

https://www.washingtonpost.com/health/2020/05/22/hydroxychloroquine-coronavirus-study/

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Botany

(70,504 posts)
1. "It's one thing not to have benefit, but this shows distinct harm,"
Fri May 22, 2020, 08:38 AM
May 2020

April 9, 2020

Trump again touts unproven drug to treat coronavirus: ‘What do you have to lose?’

That’s what Trump said Sunday during a White House news briefing on the coronavirus pandemic, adding: “I’m not looking at it one way or another. But we want to get out of this. If it does work, it would be a shame if we didn’t do it early.”

“What do I know? I’m not a doctor,” Trump said. “But I have common sense. The FDA feels good about it, as you know, they approved it.”

snip

“We don’t have time to say, ‘Gee, let’s take a couple of years and test it out, and let’s go and test with the test tubes and the laboratories,’ ” Trump said Sunday, claiming that even if it’s not effective against the coronavirus, there’s no harm in trying because “it doesn’t kill people.”


https://www.marketwatch.com/story/trump-again-touts-unproven-drug-to-treat-coronavirus-what-do-you-have-to-lose-2020-04-05

Dennis Donovan

(18,770 posts)
2. K&R - More from the same article
Fri May 22, 2020, 08:39 AM
May 2020
<snip>

“It’s one thing not to have benefit, but this shows distinct harm,” said Eric Topol, a cardiologist and director of the Scripps Research Translational Institute. “If there was ever was hope for this drug, this is the death of it.”

David Maron, director of preventive cardiology at the Stanford University School of Medicine, said that “these findings provide absolutely no reason for optimism that these drugs might be useful in the prevention or treatment of covid-19.”

Past studies also found scant or no evidence of hydroxychloroquine’s benefit in treating sick patients, while reports mounted of dangerous heart problems associated with its use. As a result, the Food and Drug Administration last month warned against the use of the drug outside hospital settings or clinical trials.

</snip>

struggle4progress

(118,282 posts)
3. "We need get those 30 million doses of hydroxycholoroquine in our National Stockpile off the shelves
Fri May 22, 2020, 08:44 AM
May 2020

and into the hands of eager Republican voters as quickly as possible, before some quack comes along and discourages people from taking this miracle drug!"

Botany

(70,504 posts)
5. I might be wrong but I would bet big bucks that Trump and Kush-Turd have invested in H.C.Q.
Fri May 22, 2020, 08:48 AM
May 2020

He was told of the coming pandemic in Nov. 2019 and it looks like instead of working to
prepare America he and Kush-Turd looked @ ways to make money on it w/hydroxycholoroquine
and his own C-19 test kits instead of the perfectly good one from the W.H.O..



And this scam @ a time when Trump was publicly deigning any problems from "the virus."
https://www.democraticunderground.com/100213462616

tanyev

(42,554 posts)
4. And healthcare workers are about to become sacrificial guinea pigs.
Fri May 22, 2020, 08:46 AM
May 2020
UK healthcare workers begin COVID-19 hydroxychloroquine trial
Study aims to determine if chloroquine and hydroxychloroquine are effective in preventing the novel coronavirus.

Healthcare workers in the United Kingdom will begin taking part in a University of Oxford-led international trial of two anti-malarial drugs to see if they can prevent COVID-19, including one US President Donald Trump says he has been taking.

The "COPCOV" study, wich begins on Thursday, will involve more than 40,000 front-line healthcare workers from Europe, Africa, Asia and Latin America to determine if chloroquine and hydroxychloroquine are effective in preventing the novel coronavirus.

In the UK, Europe and Africa, participants will receive either hydroxychloroquine or a placebo for three months. In Asia and Latin America, they will receive either chloroquine or a placebo.

https://www.aljazeera.com/news/2020/05/uk-healthcare-workers-covid-19-hydroxychloroquine-trial-200521082030076.html

still_one

(92,190 posts)
6. In fairness, enrollment in these studies is voluntary. If they become "guinea pigs", they
Fri May 22, 2020, 08:49 AM
May 2020

are doing it on a voluntary basis

In fact most involved in clinical studies are guinea pigs




still_one

(92,190 posts)
11. Absolutely. Clinical trials always allow a participant to drop out for any reason
Fri May 22, 2020, 09:16 AM
May 2020

The risk is that if they experience an adverse side effect, it may not be reversible, even if they drop out


Celerity

(43,350 posts)
8. Give it to every single motherfucking Trump voter ASAP. Give them 100 pills, tell 'em the more they
Fri May 22, 2020, 09:01 AM
May 2020

nyam up the safer they are and the bigger a patriot they become.

Rhiannon12866

(205,320 posts)
12. Not to mention those who are young and healthy
Sat May 23, 2020, 02:53 AM
May 2020

I still remember hearing about the sudden death of a girl I knew from elementary school. Apparently she got into a fight with her boyfriend who had been stationed overseas. She locked herself in the bathroom and took an anti-malaria drug that she found among his things - and she died. She was just 18.

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