Fifth diabetes medicine recalled for containing too much of a 'probable carcinogen'

[dixiegrrrrl]

Thursday, Lupin Pharmaceuticals announced its recall of Metformin Hydrochloride Extended-Release Tablets after the FDA found the Type 2 diabetes medicine exceeded standards for NDMA.
Though NDMA (N-Nitrosodimethylamine) occurs naturally in many foods, the FDA has a limit on how much should be ingested daily because it’s classified as a “probable human carcinogen.” The FDA said earlier this month it had asked five companies to voluntarily recall its Metformin after testing turned up too much NDMA.

Apotex, Amneal, Teva and Marksans Pharma previously pulled their Metformin extended release tablets. Lupin completes the list with its recall of 500 mg tablets, lot No. G901203, with an expiration date of 12/2020. The NDC numbers on the label is No. 68180-336-07.

Those taking Metformin should keep taking it until deciding on another treatment with your doctor or pharmacist. Advice from the FDA for Metformin patients can be found on the FDA’s website as well as a place to report problems with this or any other drug.

Anyone in the drug chain from wholesalers down to consumers should call Inmar Rx Solutions at 855-532-1856 to return recalled Metformin or to get questions about this recall answered.


https://www.fresnobee.com/news/nation-world/national/article243467376.html

[ProfessorGAC]

1. Nitrosoamines Are Known Health Risks

Mostly, the concerns in most foods & consumer products is overstated.
NDMA is certainly suspect because the small carbon chain makes the functional group more electronically active. Radical oxygen is a possible outcome.
The longer chain nitrosoamines found in all consumer products and most foods have much longer carbon chains, reducing the potential of radicalizing the terminus.
But, if one nitrosoamine is scary, all of them are scary.
And ingestion of possible carcinogens is truly something about which to be concerned!
But, if you hear about nitrosoamines in your dishwash liquid, or body gel consider yourself well informed, but don't panic. It's probably at such a low level that you'd have to live to 200 before you'd get cancer from it.
That stuff is not NDMA. NDMA is much worse.

[I_UndergroundPanther]

2. FUCK! I take metformin!

Well guess I will get the y in X route gastric surgery.

It can cure diabeties. Not every time,but its worth doing if I can't take metformin and all these diabeties drugs cause cancer,crotch rot and other terrifying side effects. I already have trouble dealing with the anxiety and have difficulty eating (trusting food) even tho I have lost a shitloads of weight and do keto because of the damn diabeties.

I need to get the surgery fuck this shit.

[KewlKat]

3. Thanks for posting...all of my hubby's bottles are on the recall list.

YOu'd think these pharmacy would contact patients.

we found ours on this list

[Ms. Toad]

8. It is a retail level recall -

they are not being pulled back from consumers yet. Only the spare bottles on hand in the pharmacy are being recalled at this point.

My pharmacy substituted Metformin ER form Granules - which was sued in March for this issue (lawsuit ongoing).

[I_UndergroundPanther]

4. Looked at my metformin

It's manufactured by granules pharmecuticals in Chantilly VA.

It's not extended release.
1000 mgs.

Does not look like it's on the recall list.

I hope people check thier bottles. My pharmacy put the prescription name
label on the bottle over the information I need to see,pissed me off. Peeled it off,very,very carefully.
Why do pharmacies do this?

Good luck folks hope your metformin is safe. However that could change.

[Ms. Toad]

9. You're safe, since it is not extended release.

This ONLY impacts extended release.

(But, for the sake of anyone reading and thinking Granules is safe - they were sued in March based on higher than permitted NDMA in their products. The lots the FDA tested were apparently NDMA-free, but the tests available online for Granules Metformin ER are pretty bad.)

[I_UndergroundPanther]

10. Well of course

They give shitty metformin to people on medical assistance. Fuck for profit healthcare.

[Greybnk48]

5. I take this too, for years!

I'll have to check my bottles.

[UTUSN]

6. Holy Zeus, will check mine, 850 mg 2xDA, not extended release (I think).

[Ms. Toad]

7. There is a class action against Granules (a sixth manufacture of metformin ER).

They were sued in March for this precise issue, but when the FDA tested some of their lots, they could not detect NMDA. (https://www.aboutlawsuits.com/generic-metformin-ndma-class-action-169542/)

It ONLY impacts the extended release version of metformin, not the regular release version.

The retail is currently only "retail level" - so that means that the manufacturers are only pulling it back from the retail vendors. The retail vendors are not, at this point, pulling them back from consumers.

The advice I received, when I called last week, was to hold onto any containers - in their experience retail level recalls are often followed by consumer level recalls (in which case you might get money back).

My vendor substituted medication from Granules, which I am reluctant to take based on the law suit. I may switch to the regular release.

[ARPad95]

11. My metformin ER 1,000 mg is by Ingenus and NDMA was not detected. /nt

[Hekate]

12. Weii hells' bells. Now I have to research mine.

[dixiegrrrrl]

13. Sorry for the maybe not good news......

That's the drug my doc was trying to push on me.
She thinks I might be "pre-diabetic". Yet all my sugar levels have tested as within normal range, for the past few years.
I suggested she review my lab reports and we'll talk next time I see her, and I will bring in my copies of all my lab reports which I keep in a notebook, because I don't think she really looks at them very often.

Now I'm pleased I didn't say yes and take it.