General Discussion
Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsAstraZeneca Covid-19 vaccine study on hold due to suspected adverse reaction in participant in UK
Alarge, Phase 3 study testing a Covid-19 vaccine being developed by AstraZeneca and the University of Oxford at dozens of sites across the U.S. has been put on hold due to a suspected serious adverse reaction in a participant in the United Kingdom.
A spokesperson for AstraZeneca, a frontrunner in the race for a Covid-19 vaccine, said in a statement that the companys standard review process triggered a pause to vaccination to allow review of safety data.
In a follow-up statement, AstraZeneca said it initiated the study hold. The nature of the adverse reaction and when it happened were not immediately known, though the participant is expected to recover, according to an individual familiar with the matter.
The spokesperson described the pause as a routine action which has to happen whenever there is a potentially unexplained illness in one of the trials, while it is investigated, ensuring we maintain the integrity of the trials. The spokesperson also said that the company is working to expedite the review of the single event to minimize any potential impact on the trial timeline.
An individual familiar with the development said researchers had been told the hold was placed on the trial out of an abundance of caution. A second individual familiar with the matter, who also spoke on condition of anonymity, said the finding is having an impact on other AstraZeneca vaccine trials underway as well as on the clinical trials being conducted by other vaccine manufacturers.
https://www.statnews.com/2020/09/08/astrazeneca-covid-19-vaccine-study-put-on-hold-due-to-suspected-adverse-reaction-in-participant-in-the-u-k/
Jarqui
(10,123 posts)This vaccine appealed to me because it was based on things they'd done previously with humans - so it would not be as experimental/risky
PoindexterOglethorpe
(25,853 posts)Not going blithely ahead no matter what happens.
I believe a very large number of possible vaccines are being tried, which seems like a good thing.