General Discussion
Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsAnyone been following Ivermectin use against COVID?
Ivermectin has shown some promise as having a powerful antiviral effect on COVID. I heard about Ivermectin v COVID a few weeks ago but wrote it off as the new hydroxychloroquine miracle hype. However, new data has come out which is showing this anti-parasite drug might actually be effective.
The FLCCC has added it to their COVID protocol (the FLCCC rules hydroxychloroquine as NOT effective BTW).
Hope its ok to post this info. I dont take it as quack science based on the new information coming out. This drug has been used in humans across the world for over 30 years so the safety data is known. Not without some side effects but overall very safe.
I dunno...interesting..
Dr. Andrew Hill of University of Liverpool (and WHO consultant):
https://www.arabnews.com/node/1787106/world
FLCCC COVID protocol analysis:
Page 17 shows a chart of the various treatment protocols and effectiveness (based on FLCCC analysis):
https://covid19criticalcare.com/wp-content/uploads/2020/12/Meta-analysis-of-COVID-19-therapeutics-Dr-Paul-Marik-FLCCC-Alliance-v7.pdf
HUAJIAO
(2,383 posts)In my view it is the real deal..
I took my first 2 doses last week and my first of 4 weekly doses sunday..
Here is a great link to a press conference -- spread the word !!
Drahthaardogs
(6,843 posts)And who actually prescribed this for you?
HUAJIAO
(2,383 posts)I take 6 tablets. Prescribed by a doctor in Brooklyn who is part of the FLCCC Alliance. There is a long list of docs world wide and by state on the FLCCCA website. ( My primary wouldn;t prescribe it.. he doesn't know anything about it.)
I also take Vitamin C,D
zink
quercetin
melatonin
The protocol is constantly changing as new info comes in..
crimycarny
(1,351 posts)What daily dose do you take?
Also, I cant find a list of FLCCCA doctors per state on their website. Do you have a link?
HUAJIAO
(2,383 posts)It was on the page with PHYSICIANS list
ill keep looking
In the meantime
here is the protocol
https://covid19criticalcare.com/wp-content/uploads/2020/11/FLCCC-I-MASK-Protocol-v7-2020-12-27-ENGLISH.pdf
I will do more research on the FLCCCA physicians. Supposedly Brazil is starting to use Ivermectin in their fight with COVID and I know a doctor there...
HUAJIAO
(2,383 posts)crimycarny
(1,351 posts)Awesome, thanks so much! I feel safer knowing I have something in my back pocket for family
HUAJIAO
(2,383 posts)You have to put it in your mouth...
crimycarny
(1,351 posts)A friend of mine visits his daughter in Mexico several times a month and he was able to get several boxes of Ivermectin. They sell it OTC in Mexico.
HUAJIAO
(2,383 posts)You can follow the protocol on the FLCCCA website you like.. but they tweak it is they learn more.
HUAJIAO
(2,383 posts)HUAJIAO
(2,383 posts)crimycarny
(1,351 posts)I was sort of afraid to post this as I wasnt sure if it would be seen as pseudo science. A friend of mine told me about it. She got a prescription from her doctor (who also believes in it) but the pharmacy refused to fill it. I was able to get my hands on some which Im holding onto in case my husband gets sick. He has Type II diabetes and a BMI of 30.6 (BMI over 30 a risk factor).
I was told one tablet (6 mg) at day 1, one tablet at day 3, and one at day 7.
Important thing for people to know is NOT to take animal formula (Heartguard for heart worms is Ivermectin). Thats what worries me...that people wont be able to get the prescription meant for humans and will take animal formulated version.
HUAJIAO
(2,383 posts)They also have info on the dosage, protocol etc..
Never heard of just 1 pill.
here
https://covid19criticalcare.com/
crimycarny
(1,351 posts)Lots of info on their website and having a tough time finding things. Of course being distracted by Georgia senate race doesnt help, lol.
Wawannabe
(5,641 posts)Ok for the animals but I dont know about me??
nsd
(2,406 posts)It has been important in the (near) eradication of river blindness in South America and Africa.
See: https://mectizan.org/
Its discovery won William Campbell and Satoshi Omura the Nobel Prize in medicine in 2016, and is one of the reasons Merck is considered a great company.
It's not just an animal wormer.
HUAJIAO
(2,383 posts)for a number of diseases....
Wawannabe
(5,641 posts)Thanks for the info pardner
csziggy
(34,136 posts)https://www.webmd.com/drugs/2/drug-1122/ivermectin-oral/details
I checked on the safety for humans decades ago - we used liquid ivermectin intended for injection in cattle to worm our horses. In horses, injection is not recommended since it can cause nasty abscesses, so we'd draw it up in a big syringe and squirt it in the horses' mouths. Some of the horses got smart - one in particular would put her tongue up against the tip of the syringe so when we tried to squirt it, it would squirt back at us. I got a mouthful once. No wonder the horses hated it - it's nasty bitter stuff. I was worried it might not be safe for me so I checked and it is safe for humans. My veterinarian said I wouldn't have to worry about worms in my gut for a few months!
Later they came out with a paste version that made it easier to put it in the horses' mouths and harder for the horses to get it out. It was more expensive, but less hassle. That's the same format that most horse de-wormers are manufactured in so we were already used to administering it that way.
ETA - we also used the liquid for treating our dogs for worms, including heartworms!
crimycarny
(1,351 posts)She is worried she wont be able to get the liquid for her dog if people start gobbling it up. FDA needs to look into this but I fear they are overly cautious after hydroxychloroquine disaster.
Evidence very strong for prophylactic application. Cheap, easy to manufacture. Why not take a serious look at it since the vaccine is taking forever to roll out? 30 years of safety data in humans too.
csziggy
(34,136 posts)For my horses, probably 500 mL or maybe 1000 mL. It'd let me treat the horses and our two dogs for a year. She might want to check places lit Jeffers Vet Supply - https://www.jefferspet.com/products/injectable-ivermectin-for-cattle-and-swine
For dogs she could get a 50 mL and it would last a while. It's been twenty years since we put our last dog to sleep, so I don't remember the dosages. It was x cc per pound of weight for the dog. And about the same for the horses.
crimycarny
(1,351 posts)I will pass that on to my sister!
csziggy
(34,136 posts)I bought from Jeffers because they are close and if I got an order in by 4 PM I'd often get the stuff the next day. But they are in Alabama and I am sure the owners are dyed red Republicans.
It's not a prescription item for animals so it's easy to shop around.
superpatriotman
(6,247 posts)Plus prednisone and Z Pak
abqtommy
(14,118 posts)Chakaconcarne
(2,444 posts)Ivermectin Ivermectin has also been proposed as a potential therapy based on in vitro activity against SARS-CoV-2, but the drug levels used in vitro far exceed those achieved in vivo with safe drug doses [129]. In a retrospective review of 280 patients hospitalized with COVID-19, receipt of ivermectin was associated with a lower mortality rate; however, patients who received ivermectin were also more likely to receive corticosteroids, highlighting the potential for confounders to impact the findings of nonrandomized studies [130]. Various clinical trials of ivermectin are underway, but the only results available thus far are from low-quality unpublished trials. As with other interventions that are not supported by high-quality data, we do not use ivermectin outside of clinical trials.
https://www.uptodate.com/contents/coronavirus-disease-2019-covid-19-management-in-hospitalized-adults/print?sectionName=EVALUATION&topicRef=128404&anchor=H478803960&source=see_link
In progress:
https://clinicaltrials.gov/ct2/show/NCT04602507
crimycarny
(1,351 posts)In regards to the higher doses used in in vitro.
https://covid19criticalcare.com/i-mask-prophylaxis-treatment-protocol/faq-on-ivermectin/
How could ivermectin be effective if the tissue concentrations needed to kill the virus would require a patient to take massive doses to achieve?
The theory that ivermectins anti-viral activity is dependent on unachievable tissue concentrations is incorrect as follows:
In the cell culture study by Caly et al from Monash University in Australia, although very high concentrations of ivermectin were used, this was not a human model. Humans have immune and circulatory systems working in concert with ivermectin, thus concentration required in humans have little relation to concentrations used in a laboratory cell culture. Further, prolonged durations of exposure to a drug likely would require a fraction of the dosing in a short-term cell model exposure.
LetMyPeopleVote
(145,126 posts)LetMyPeopleVote
(145,126 posts)The RWNJ sites are really pushing this quack cure. This medicine is for horse deworming
Link to tweet
Thats the conclusion of the Together Trial, which has subjected several purported nonvaccine treatments for COVID-19 to carefully designed clinical testing. The trial is supervised by McMaster University in Hamilton, Canada, and conducted in Brazil.....
Among the 1,500 patients in the study, he said, Ivermectin showed no effect whatsoever on the trials outcome goals whether patients required extended observation in the emergency room or hospitalization.
In our specific trial, he said, we do not see the treatment benefit that a lot of the advocates believe should have been seen.....
The findings on Ivermectin are yet another blow for advocates promoting the drug as a magic bullet against COVID-19. Ivermectin was developed as a treatment for parasitical diseases, mostly for veterinarians, though its also used against some human parasites.
crimycarny
(1,351 posts)I am NOT anti-vax but I was truly hoping that Ivermectin would have a positive effect in fighting COVID so I wanted to keep a open mind. But I felt had to stay silent in order not to be mocked as someone who believes in using horse dewormer (despite the fact its been used in humans for almost 40 years).
Oddly there was an article about 3 days ago that a common Tapeworm drug is showing promise against COVID. Something about it interrupts the virus replication process.
https://healthcare-in-europe.com/en/news/anti-tapeworm-drug-shows-promise-against-covid-19.html
So maybe there is something weird about anti parasite meds that muck up the replication process for COVID and other RNA viruses. Im curious about the science. Ive also been fully vaccinated will get a booster if FDA says its needed. I just like keeping an open mind.