Pfizer CEO vows to speed up new vaccine development to under 100 days to combat the 'high likelihood

[applegrove]

https://www.businessinsider.com/pfizer-ceo-said-in-future-covid-19-vaccines-wont-be-effective-2021-1

Pfizer CEO vows to speed up new vaccine development to under 100 days to combat the 'high likelihood' that current COVID-19 shots become ineffective

Patricia Kelly Yeo Business Insider

"SNIP.....

At a virtual Davos economic forum, Pfizer CEO Albert Bourla said there's a "high likelihood" that COVID-19 vaccines will become ineffective in the future.

Bourla said the company is working to ensure it can produce a high efficacy vaccine in 100 days or less, a radically sped up development timeline

Former BARDA director Richard Hatchett also stressed the need for governments to see infectious diseases as an "existential threat to our society."

......SNIP"

[colsohlibgal]

1. Good News

But......I don’t recall on any of my previous inoculations, be it for Polio, Measles, MMR, that it was only 75% effective or 66% or whatever %. This is a first and it’s troubling.

[applegrove]

2. Pfizer is 95% right now after 2 vaccinations. Yes they will go down in effectiveness

as varients evolve and evolve.

[Blue_true]

6. SARS-COV-2 is a beast that we have not seen in millennia.

It is possible that the four coronaviruses that cause common colds were deadly to humans when they jumped to our species hundreds of thousands or even millions of years go. But over time the bodies of the human beings that survived them adapted to them and muted their impact, along with the viruses mutating to become more infectious, but less deadly (a wet dream for a virus since it acquires and keeps many live hosts)

I have for a while believed that SARS-COV-2 would mutate to slip vaccines, we don’t have a vaccine for the common cold. It may take hundreds of years, thousands of years, ect for our bodies to develop an accommodation with SARS-COV-2, we don’t have that type of time in terms of deaths, so bandages that SARS-COV-2 slips out of will for a long while be our best defense, IMO.

[Klaralven]

15. We've never been so concerned about the fine print.

One dose of MMR vaccine is 93% effective against measles, 78% effective against mumps, and 97% effective against rubella.

Two doses of MMR vaccine are 97% effective against measles and 88% effective against mumps.

https://www.cdc.gov/vaccines/vpd/mmr/public/index.html

[KentuckyWoman]

30. The Salk Vaccine was 60-70%

it was enough. They tweeked the vaccine over time. Now I think it takes 4 shots to be fully immunized for polio.

[HUAJIAO]

3. republicans are an "existential threat to our society."

maybe pfizer can develop a vaccine against them.

[applegrove]

4. Variants develop because there there is so much virus out there: meaning

more people in the world are infected. So if we had kept down the number of cases with strict measures and masks everywhere the variants would be less likely to develop. Those who tried to put their country into herd immunity, did not take it seriously to start with, prioratized businesses over health or are and were against masks should be sued for dereliction of duty.

[Blue_true]

9. Your analysis on mutants appears right.

A DU member posted a presentation by a expert. The reason why responsible scientists (meaning not Scott Atlas) want to quash a virus as quickly as possible is the longer the virus stays unchecked, the more mutants it can form, and eventually, some of those mutants may be very problematic.

[applegrove]

11. And if you have so many variants you can't stamp it out with vaccines.

So you end up having to create new vaccines all the time. We may be wearing masks forever. I just got an order for another 2 dozen masks from a family member. And i was thrilled to cut up my designer 25 year old sheets as they have the right thread count to be effective. The cotton material i bought online was crap so i threw it out.

[HUAJIAO]

12. what is 'effective," in this case ?

And BTW each response here under my response fits right in with republicans as well as Covid.

[applegrove]

18. I don't know the thread count. They are thick and pure cotton. Two layers.

And they mold really well around my face. Think, quality cotton from 25 years ago. Great print too.

[HUAJIAO]

19. That's a cool looking mask. I like the way so many are designing their own masks.

provides a lot of variety and self-expression.

Thing is, the 3M(for example) N95 masks


"The filtration material on the mask is an electrostatic non-woven polypropylene fiber."

"The two outward protective layers of fabric, covering the inside and outside of the mask, are created using spun bonding."

It is my understanding that one way this masks works is by forcing virus aerosol to keep changing direction enough times that it, just runs out of speed and gets trapped. Cotton masks will only slow it down and are better at protecting others than protecting the wearer. Frankly, I never wear a cotton or 'medical' mask.. In low risk situations I wear a single ear loop N95 or CDC approved KN95 mask because I can get it on and off quickly if need be. In more serious environments like grocery shopping I wear double strap N95- either 3M, Uline, Makrite etc... There are a few others.

[applegrove]

20. Oh i did not mean to imply cotton masks were better than N95 or surgical

masks. Just as homemade go, good quality cotton is best. I've seen charts. And yes if it is to protect others that is important.

[HUAJIAO]

21. If you can get polyester, it is better than cotton.

[applegrove]

22. Never saw that anywhere.

[Blue_true]

25. If the lasted as long as you indicated, likely in the 250-350 thread count range.

If they have a “silky” texture, they are in the 350+ thread count range.

I used to be into high thread count sheets when I was younger, they just felt better against my body. As I have aged, it doesn’t seem to make a difference.

[applegrove]

26. They are silky. Thick. And they are not prone to holes or tears. Old time cotton sheets.

I've had a duvet cover for 2 years that i love. There are tears everywhere it is made so cheaply. The cotton is so thin and probably made to just live two years. It tears for no reason.

[Blue_true]

27. If they are silky and thick, likely 350+ thread count.

Yes, those last for years and years, don’t rip or develop holes. Even direct exposure to concentrated bleach don’t have a big effect on them. They are hard to find though, typically I found them only in specialized bed and bath shops, during that period, I never shopped online, I just today that I can find them online.

[Blue_true]

7. And call it the "Malignant Cap Vaccine". nt

[Initech]

10. And version Q.Batshit.01 is quite infectious.

And known to be highly toxic. If you know anyone who is infected, they need to be isolated and quarantined. Otherwise they can cause great harm to themselves or others.

[HUAJIAO]

13. right on the money..

Then there is version PC .01... Pseudo Christian.

[area51]

5. "...'high likelihood' that current COVID-19 shots become ineffective..."

[Blue_true]

8. Never surprised me.

SARS-COV-2 has four cousins among the common cold viruses, we never have solved them. My uneducated belief is that each of the common cold coronaviruses were deadly to human beings in the distant past, but our evolution developed an accommodation with them.

[Klaralven]

16. Viruses evolve in the direction of higher infectiousness, lower mortality

It doesn't improve viruses chances of replicating if it kills its host.

[ananda]

17. How long?

Hopefully Covid will evolve that way, but I wonder how long
that takes.

[Blue_true]

24. My guess would be many years.

Since we have so many people making themselves hosts, the virus will likely mutate in a number of directions, including deadlier, before converging at a highly infectious, but not lethal platform (like the common cold coronaviruses), that could take one or two decades or even longer, my read, but uneducated guess.

[ananda]

28. I think that assessment makes a lot of sense.

So we really need good vaccines now, on an ongoing basis.

[Blue_true]

29. Yes, modern vaccine technology will certainly be a massive advantage for us.

Fortunately we definitely are in better shape than cave people or Middle Ages people were when they faced off with the common cold coronaviruses for the first time. Although we likely have the same percentage of anti-social idiots running around as they did.

[Blue_true]

23. Yes. I believe that is why the four common cold coronaviruses

make us sick, but generally don’t kill us. Like Michael Corleone would have said “killing you is bad for business”, so the 4 coronaviruses evolved to spread in us, but keep us upright and alive. BUT, when each of them first jumped to our species, that likely was not the case, they killed us an a comparatively high rate.

[Wounded Bear]

14. Simple explanation...the more of it that is out there, the more chances there are to mutate...nt