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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsA 70 yr old friend of mine is not planning to get the COVID vaccine.
She is a retired health care worker and a devout Catholic. She is pro-life, and thinks the way vaccines are made (stem cells) goes against her values.
Does anyone know if this is true (stem cells are used in the production of vaccines), and if so is it true for all the available vaccines?
DLCWIdem
(1,580 posts)I don't think it's made of stem xells.
Ms. Toad
(38,506 posts)The two available now are made using mRNA - which trains our body to make fragments of the protein spikes, which attach to cells in our bodies. Our immune system recognizes the fragments as foreign and triggers an immune response.
Neither contain fetal stem cells, but both used the line used the fetal cell line HEK 293 in the confirmation phase to ensure the vaccines work.
lapfog_1
(31,849 posts)tell her to get the J & J vaccine or the Oxford vaccine
no point trying to change her mind on the whole stem cell thing
milestogo
(22,955 posts)Who is the maker of the mrna vaccine?
LisaL
(47,385 posts)mRNA is synthetic.
lapfog_1
(31,849 posts)vaccines are messenger RNA vaccines... it is likely the reason they are 95 % effective against SARS-Cov-2.
not only that, they can be easily tweaked against mutations of the virus ( if we need to). That said, the other successful vaccines are as effective in preventing death or serious illness as the mRNA.
I plan on getting the moderna vaccine myself.
LisaL
(47,385 posts)mRNA vaccines are not made using stem cells.
lapfog_1
(31,849 posts)the facts will not matter to a 70 year old that always associates stem cells with aborted fetal tissue.
LisaL
(47,385 posts)Vaccines are used to induce immunity. mRNA in vaccines are used to make spike protein. Immune system is then able to recognize spike protein if a person is infected with covid and put on a defense.
lapfog_1
(31,849 posts)and the "anti-vaxxers" have run with it
Blue_true
(31,261 posts)The only thing that has is the Regeneron that Trump took.
Miguelito Loveless
(5,674 posts)Blue_true
(31,261 posts)Miguelito Loveless
(5,674 posts)and you'll never convince the religiously insane, thus the edict of their leader.
Blue_true
(31,261 posts)where only one side will prevail.
The Velveteen Ocelot
(130,201 posts)Celerity
(54,169 posts)The Velveteen Ocelot
(130,201 posts)and therefore the only ones the OP's friend would be likely to get - so the only relevant info at this time.
Celerity
(54,169 posts)process (see my origianl reply) plus both the Moderna and Pfizer vaccines used them in testing leading up to the development (so I was too broad in my agreeing with that part of your reply). That said, the Moderna and Pfizer vaccines do not use them in their manufacture though and Catholic Organisations say those two are not morally compromised.
https://www.nbcnews.com/health/health-news/how-cells-taken-decades-old-fetal-tissue-are-used-covid-n1242740

AstraZenecas COVID-19 vaccine is in Phase 3 trials in the US and also uses them for manufacture.
The fifth vaccine, which has shown promise in monkeys and is headed for human trials as soon as this summer, is what is known as a protein subunit vaccine. Researchers at the University of Pittsburgh use HEK-293 cells to manufacture the coronavirus spike proteina vital part of its structurewhich is used to trigger an immune response. The vaccine is delivered through a skin patch with 400 tiny needles.

The Velveteen Ocelot
(130,201 posts)I imagine there are quite a lot of drugs and treatments that use stem cell research or components that nobody even knows about.
Celerity
(54,169 posts)I personally think the entire thing is based off the madness that is the forced-birther, antiabortion stance that flows from religions (for the most part), but hardcore religious zealots are almost impossible to reason with.
Ms. Toad
(38,506 posts)to confirm effectiveness.
https://www.nebraskamed.com/COVID/you-asked-we-answered-do-the-covid-19-vaccines-contain-aborted-fetal-cells#:~:text=When%20it%20comes%20to%20the,you%20receive%20from%20your%20doctor.)
matt819
(10,749 posts)I would put money on the likelihood that she would come up with another reason to refuse the vaccine.
MustLoveBeagles
(15,814 posts)EarnestPutz
(2,843 posts)....current vaccines have anything to do with human DNA, let alone stem cells. The Moderna vaccine isn't even based on the natural RNA of the virus, but a synthetic version.
PDNIIDGTER
Pobeka
(5,000 posts)Ms. Toad
(38,506 posts)but in testing, which will matter for some people.
https://www.nebraskamed.com/COVID/you-asked-we-answered-do-the-covid-19-vaccines-contain-aborted-fetal-cells#:~:text=When%20it%20comes%20to%20the,you%20receive%20from%20your%20doctor.)
Blue_true
(31,261 posts)fetal stem cells for either development or testing purposes, fundamentalists are likely going to say that is immoral. Yet those same people worshipped the most immoral person that I have seen in my lifetime. A rational person reaches a point where it is wise just to say screw you to them. I honestly wish that someone comes up with a vaccine or cure for SARS-COV-2 where people that take it are totally protected and cant be infected by the anti-vaxxers, anti-maskers and religious fundamentalists, in such a case, I would not care one iota if the fundamentalists, anti-vaxxers or anti-mask people took vaccines or wore masks
Ms. Toad
(38,506 posts)If the question is whether fetal stem cells were used in developing the current vaccines, the answer is yes. Not to identify two steps of the path from idea to finished vaccine and assert that they weren't used in those two steps.
Facts matter. We should not be in the business of spreading alternative facts. We may not like how someone responds to facts. But telling somoene fetal cells were not involved in creating these vaccines is like telling someone there's no meat in a dish because we think their objections to eating meat are silly.
Blue_true
(31,261 posts)It is one thing to design a vaccine using stem cells versus testing a vaccine designed independently of stem cells using the most reliable method of showing that those vaccines are safe for human use. Now, a person can say that distinction doesnt matter, to them I say bullshit, it does matter as much as night versus day. I have no interest in catering to people that dont respect facts at all, so if I slice things thin when dealing with them, so be it.
Beyond the above, the key reason why I have no use for those people or their claims, is their grotesque hypocrisy concerning life and its sanctity. They cherish a fetus, but are ok with with a child drowning with her father as both tried to escape brutal killers in their home country, or with their cherished leader separating families who were running for their lives, seeing us as their only safe harbor. They want children born that the parents cant or wont support financially, only to turn around and deny those same children medical care and nutritious food if they had their way.
Union General William T. Sherman was quoted as saying on waging war You can not qualify war in harsher terms than I will. Many fundamentalists, anti-maskers, anti-vaxxers take a harsh view toward that which they disapprove of, like it or not, I view people that value life as being in a moral and philosophical war with those people and kindness toward them only leads to more destruction.
Ms. Toad
(38,506 posts)or whether the use of stem cells matter at all.
But facts are facts. These two vaccines would not be on the market without using stem cells in the process of testing them. When the question is whether stem cells were used in developing the vaccines the answer is yes. It is factual to clarify how they are used, but not to state that they were not used.
Whether you respect distinctions others make is opinion - everyone is entited to their own opinion. I'm not challenging your opinion - I am challenging the repeated (false) assertions (by many here) that the two vaccines on the market are free from the use of embryonic stem cells.
Blue_true
(31,261 posts)I know that in chemical mixtures, even if I use a trace of a chemical, I must list it in the ingredients list.
But the nonsense over cells that are only philosophically attached to the original ELECTIVE abortion that was done in the seventies is a bridge too far for me. I can have a Chemist synthesize a copy of a rare chemical from a plant, but once that is done, if the synthesis is done daily with no connection to the original plant, at what point does a rational person argue that there still is a relationship to the original plant?
Ms. Toad
(38,506 posts)At one time I was a vegetarian because I grew up on a farm and - even on a family farm that was run ethically by most standards - I found the cruelty to animals unacceptable (castrating pigs and calves without anesthesia, for example).
So if I want to be free from participation in that cruelty, where is the line?
Not eating meat is the easy question - but -
Can I wear leather? If the animal was killed recently to make whatever it is, probably not. But can I wear second-hand leather - that comes from animals who were killed decades ago (so nothing I can do can alter what happened to them - i.e. no new animals are being killed to make my shoes) - or is it better to put their hides to good use to at least ensure that they did not suffer only to have their skins tossed in the trash can?
Can I drink milk from grass fed cows who are allowed to roam free and gently milked by hand? If that seems OK, what about the calves that were born in order to generate that milk - must they be allowed to live their lives out running happily about a pasture, un-castrated, not dehorned, not ear tagged, not branded, not be slaughtered for food? Or would it be OK to slaughter them humanely (as long as we didn't inflict pain on them for our convenience - such as branding)?
Many on the left are passionate about how we treat animals - and wrestle with line drawing.
Even though I don't agree with the moral dilemma many on the right feel as to abortion, I recognize it as a similar dilemma. If they truly believe abortion is immoral (and some do), where is the line? That question - as to use of stem cells from a long ago voluntary abortion for testing - is equivalent to my question about the use of second-hand leather or how we treat the calves associated with milk production.
Blue_true
(31,261 posts)line that a persons sense of what is moral cause them to fall solidly on one side. What I dont get is some of the people that oppose vaccines were perfectly ok with Trump getting Regeneron. The two approved vaccines have an minor association with stem cells, Regeneron depends on them, from what I understand of it. So, the issue seems to be application of selective morality in my mind, and that I resent heatedly.
Ms. Toad
(38,506 posts)but there definitely was one. So - yeah. Anyone who approved of Trump getting Regeneron but is now opposing the vaccine becuase of the fetal stem cell connection is a hypocrite. I can't think of a way to approve of one, but not the other.
Celerity
(54,169 posts)snip
Cells derived from elective abortions have been used since the 1960s to manufacture vaccines, including current vaccines against rubella, chickenpox, hepatitis A, and shingles. They have also been used to make approved drugs against diseases including hemophilia, rheumatoid arthritis, and cystic fibrosis. Now, research groups around the world are working to develop more than 130 candidate vaccines against COVID-19, according to the World Health Organization; 10 had entered human trials as of 2 June.
At least five of the candidate COVID-19 vaccines use one of two human fetal cell lines: HEK-293, a kidney cell line widely used in research and industry that comes from a fetus aborted in about 1972; and PER.C6, a proprietary cell line owned by Janssen, a subsidiary of Johnson & Johnson, developed from retinal cells from an 18-week-old fetus aborted in 1985. Both cell lines were developed in the lab of molecular biologist Alex van der Eb at Leiden University. Two of the five vaccines have entered human trials (see table, below).

In four of the vaccines, the human fetal cells are used as miniature factories to generate vast quantities of adenoviruses, disabled so that they cannot replicate, that are used as vehicles to ferry genes from the novel coronavirus that causes COVID-19. When the adenoviruses are given as a vaccine, recipients cells begin to produce proteins from the coronavirus, hopefully triggering a protective immune response. The fifth vaccine, which has shown promise in monkeys and is headed for human trials as soon as this summer, is what is known as a protein subunit vaccine. Researchers at the University of Pittsburgh use HEK-293 cells to manufacture the coronavirus spike proteina vital part of its structurewhich is used to trigger an immune response. The vaccine is delivered through a skin patch with 400 tiny needles.
The fetal cell lines are key to producing both types of vaccine. HEK-293 [cells] are essential for making protein subunit vaccines, says Andrea Gambotto, a vaccine scientist at the University of Pittsburgh School of Medicine and the vaccines lead developer. Their human origin is important, he says: Cultured [nonhuman] animal cells can produce the same proteins, but they would be decorated with different sugar molecules, whichin the case of vaccinesruns the risk of failing to evoke a robust and specific immune response. (Among the developers of the five vaccines, only Gambotto responded to a request for comment.)
David Prentice, vice president and research director at the Charlotte Lozier Institute, which opposes abortion, notes researchers making adenovirus vaccines have modified HEK-293 cells to be adept at packaging new genessuch as those that direct cells to assemble the coronavirus spike proteininto adenoviruses. But he adds that other technologies are available, including using cells captured from amniocentesis that are engineered to make replication-deficient adenoviruses. The use of cells from electively aborted fetuses for vaccine production makes these five COVID-19 vaccine programs unethical, because they exploit the innocent human beings who were aborted, Prentice and a co-authormolecular biologist James Sherley, a Lozier Institute associate scholar and director of the adult stem cell company Asymmetrexwrote in a position paper published last month.
snip
milestogo
(22,955 posts)Blue_true
(31,261 posts)They are hypocrites and I am well passed done with them or their false concerns.
LisaL
(47,385 posts)They are made from synthetic mRNA surrounded by lipid.
Ms. Toad
(38,506 posts)Their effectiveness was confirmed using stem cells from the HEK 293 line.
https://www.nebraskamed.com/COVID/you-asked-we-answered-do-the-covid-19-vaccines-contain-aborted-fetal-cells#:~:text=When%20it%20comes%20to%20the,you%20receive%20from%20your%20doctor.)
ismnotwasm
(42,674 posts)Hes the spiritual leader of Catholics.
JustABozoOnThisBus
(24,658 posts)What would Benedict have done? We need to cast chicken bones to determine this.
Blue_true
(31,261 posts)ismnotwasm
(42,674 posts)My daughter is always telling me hes not a liberal as people make him out to be which is very true. We are all Catholic, well, not me, not really.
Squinch
(59,295 posts)Blue_true
(31,261 posts)100% non-infectable by the idiots and fundamentalists, I would be perfectly ok then with them plying their BS.
sanatanadharma
(4,087 posts)They deny their God, those who reject the means made by men made in the image and likeness of their God.
They fail to see the healing grace of wisdom and knowledge in vaccines.
They claim the creation is a gift of the creator and yet reject the cures made available by the minds, hands and resources within that gift.
The same people who will donate their mortal remains to the benefit of others, reject the donations made available to them by the other.
Serious failures of fact, logic and morality lead to seeing and fearing the snake in the grass.
Rational embrace of fact, logic and morality reveals the mistake of projecting a snake upon the reality of the lanyard on the lawn.
The Velveteen Ocelot
(130,201 posts)The logical extension of refusing to use the products of science because of some fear that God would disapprove would have us still living in caves in the dark.
Blue_true
(31,261 posts)think up is outside the design that God has for us, that include use of fetal stem cells for healing. If God didnt intent for us to use such a method, our minds would have been incapable of discovering its existence.
dalton99a
(93,621 posts)Pope Francis suggests people have moral obligation to take coronavirus vaccine
Jan 11, 2021
by Joshua J. McElwee
Rome Pope Francis suggested that people have a moral obligation to receive one of the new coronavirus vaccines as soon as possible, revealing in a new interview that he expects to get his own first dose this week.
"I believe that morally everyone must take the vaccine," the pontiff said in a Jan. 10 interview for Italy's TG5 news program. "It is the moral choice because it is about your life but also the lives of others."
The pope, who said he has already made an appointment with the Vatican's health service for his own inoculation, also lamented that some people are saying they will not take a vaccine.
"I do not understand why some say that this could be a dangerous vaccine," said Francis. "If the doctors are presenting this to you as a thing that will go well and doesn't have any special dangers, why not take it?"
---------------
https://www.cnn.com/2021/01/14/europe/pope-francis-covid-19-vaccine-intl/index.html
Pope Francis and former Pope Benedict get first dose of Covid-19 vaccine
By Hada Messia, CNN
Updated 8:49 AM ET, Thu January 14, 2021
Hekate
(100,133 posts)northlake9
(65 posts)My wife and I have decided that no vaccine no visits, even members of the family. Our home our rules. Make the choice take responsibility.
yellowdogintexas
(23,671 posts)last April.
One of his brothers (and his wife) are on the FWPD and I would suspect they are tested regularly to avoid spreading it. Their sister and the other brother are leaning towards not getting the vaccine; they are heavily influenced by hogwash, though
There is another brother in Tennessee who is exercising proper cautions.
Mr.Bill
(24,906 posts)will go to great lengths to find a reason to avoid them. And that includes Nurses. Until about five years ago it included me. I volunteer at a hospital and about 20% of the employees are refusing the vaccine. Every year they refuse the flu shot even though that means they will have to wear a mask at all times in the hospital for the entire flu season. You would also be surprised at how many of hospital employees are smokers. They are not allowed to smoke on hospital property any more, so they walk a few hundred yards, go a cross the street and stand in a vacant lot and smoke during their breaks.
My wife is a retired RN and she tells me stories about patients who are covered with tattoos and have multiple facial piercings but are terrified to get a shot they need.
LisaL
(47,385 posts)Mr.Bill
(24,906 posts)but it happens.
LisaL
(47,385 posts)NT
Mr.Bill
(24,906 posts)get some kind of sexual thrill out of having the pain inflicted on them.
maxsolomon
(38,535 posts)and maybe some other's, too.
Blue_true
(31,261 posts)relative to them is fine with me.
maxsolomon
(38,535 posts)that aren't reachable through logic or pleading. because we're in an epistemological crisis of GOP/Trump/RW/Christofascist Putin-styled disinformation, it's going to be higher than it would otherwise.
not much to do about it but work around it.
BGBD
(3,282 posts)How it is "pro-life" to put other people lives at risk my not getting vaccinated.
winstars
(4,277 posts)mmbrevo
(123 posts)Wasnt he given something that was derived from stem cells? Maybe shes thinking of that.
Blue_true
(31,261 posts)Lots of fundamentalists said that it was ok for him to have taken the treatment. The conditionality of their morality is sickening to watch.
Hypocrisy.
Blue_true
(31,261 posts)Regeneron that was given to Trump. The vaccines that President Biden and Vice President Harris took were designed without the use of stem cells.
I have gotten to the point where I am no longer yielding at all to fundamentalists, I am now more than willing to get into their faces, after seeing how they worshipped the most immoral person that I have seen in my lifetime.
You should confirm what I wrote about Regeneron, once that is done, I would get into your friends face and point out to her that ONLY Donald Trump has used a Covid product that was designed around stem cells, and that the mRNA vaccines that President Biden and Vice President Harris took never relied on stem cells, so she should take either the Pfizer or Moderna vaccine to protect herself, doing so wont violate any of her religious beliefs.
Yeehah
(6,351 posts)Try to reason with her and she likely will come up with some other kook excuse for not getting vaccinated,