UK Launches 'World First' Trial Mixing Different Covid Vaccines for First and Second Doses
NBCWashington
LONDON A trial is being launched in the U.K. to explore whether using different Covid-19 vaccines for the first and second doses works in a bid to make nationwide vaccination programs more flexible.
The trial, being led by the University of Oxford and run by the National Immunisation Schedule Evaluation Consortium, will evaluate the feasibility of using a different vaccine for the initial "prime" vaccination to the follow-up "booster" vaccination.
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"If we do show that these vaccines can be used interchangeably in the same schedule this will greatly increase the flexibility of vaccine delivery, and could provide clues as to how to increase the breadth of protection against new virus strains," Matthew Snape, chief investigator on the trial and associate professor in Paediatrics and Vaccinology at the University of Oxford, said on Thursday.
The trial, which is formally known as the "COVID-19 Heterologous Prime Boost study" but has been dubbed the "Com-Cov" study, will recruit over 800 volunteers aged 50 and above in England to evaluate the four different combinations of prime and booster vaccination.
https://www.nbcwashington.com/news/business/money-report/uk-to-trial-mixing-different-covid-vaccines-for-first-and-second-doses/2562014/