Can the mRNA vaccines change DNA?

[Yo_Mama_Been_Loggin]

Coronaviruses range from the common cold to more severe infections such as SARS (SARS-CoV) and MERS (MERS-CoV) and the current Covid-19 (SARS-CoV-2). As yet there is no FDA-approved vaccine to prevent coronavirus infections. These both have FDA emergency use authorization.

Two of the Covid-19 vaccines available in the US use messenger RNA technology to prevent or reduce the symptoms of Covid-19 infection. This mRNA vaccine technology is new; the consequences of altered DNA, if any, are unknown. However, others, including the CDC said that the virus would not interact with DNA.

Other scientists believe that mRNA vaccines can enter and permanently alter DNA. Like DNA vaccines, RNA vaccines use part of the genetic code of the virus to get the immune system to respond.

An article currently in preprint (not yet peer reviewed) discusses a lab study in which some pieces of Covid-19 RNA were converted to DNA and then integrated into human chromosomes.

https://www.msn.com/en-us/health/medical/can-the-mrna-vaccines-change-dna/ar-BB1fERAC

My brother refuses to get the COVID vaccine for this reason.

[JoeOtterbein]

1. We really do need that vaccine for the...

...stupid.

[Initech]

3. Sadly I don't think there will ever be a vaccine for that.

[greenjar_01]

27. Seriously

YEEEESH with these people.

[Bettie]

2. Will we get superpowers?

Because I would totally be down with that.

[underpants]

4. 😄

[dflprincess]

14. I'd be happy if it would just tighten up my jaw line

and maybe return my metablolism to what it was when I was twenty.

[Bettie]

16. I'd totally take that too

Oh, to be twenty again with the things I know now! My life would be SO much better.

[Yavin4]

23. Yes, but you'll have to wear tights and a cape.

So, there is that.

[Bettie]

26. No capes

you can get sucked into a jet engine if you wear a cape with your super suit!

[Yavin4]

31. But you still have to wear tights.

Probably a onesie.

[Bettie]

41. That's cool...

others may not think so...

[Laurelin]

35. Hi Edna

😀

[Celerity]

5. Covid-19 Vaccines Can't Alter Your DNA, Here's Why

By Victoria Forster

postdoctoral research scientist focusing on childhood cancers and new, targeted cancer therapies


https://www.forbes.com/sites/victoriaforster/2021/01/11/covid-19-vaccines-cant-alter-your-dna-heres-why/?sh=7b6fe6f52491

As millions of people around the world are given vaccines against Covid-19, some people are still reluctant to get the shot. There are several common reasons for this ranging from some which are more reasonable to the downright absurd (think 5G and microchips). One of the most popular circulating mistruths at the moment is that mRNA vaccines will alter your DNA, with pseudoscientific content flooding social networks such as Twitter, Facebook and YouTube. The good news is that they simply can’t do this, which will come as a disappointment to some who were hoping that this might be their chance for superpowers, but where did this belief in DNA-changing vaccines come from? “I think people are concerned that because this is genetic material injected into the body, could it somehow mix in with your own genetic material and change it,” said Sara Riordan, President of the National Society of Genetic Counselors.

But there are crucial differences between DNA which carries all of the information we inherited from our parents and mRNA, which the Moderna and Pfizer/BioNTech vaccines are made of. DNA is double-stranded, very very long and bundled up tightly together inside a part of the cell called the nucleus. mRNA is a single-stranded copy of a small part of DNA, which is routinely made in the nucleus, but then released into the main part of the cell so that the instructions it carries can be ‘read’ and made into a variety of proteins needed by the cell. “mRNA is naturally made by the body, it encodes instructions for your body's cells to make protein.

Any mRNA vaccine has the same purpose, to teach and train your body to make an immune response toward a particular pathogen, so if the pathogen gets into your body, your immune system can attack it,” said Riordan. In the case of mRNA vaccines against Covid-19, these are not made in the nucleus, rather they are injected into the arm to tell muscle cells how to make part of the viral “Spike” or “S” protein, a tiny part of the SARS-CoV2 coronavirus, which on its own has none of the negative effects of the virus itself. “What’s really reassuring about these mRNA vaccines, the mRNA never even goes into the nucleus, the part of the cell contains all of your own DNA and instructions,” Riordan added.

So how do they actually work?

mRNA- based vaccines are a bit like standing in your kitchen and thinking what to make for dinner. You know you’ve got all of the ingredients to make a meal, but you don’t exactly know how to make it. So you download a recipe online, put everything together using ingredients and equipment you already have in your kitchen and eat your dinner. The vaccines are simply the recipe, injecting it into your arm is simply giving specific information to your cells and letting them read it. Your cells expertly assemble the tiny part of the Spike protein from ingredients and equipment which they already have. After this, the immune system quickly goes after the spike protein fragment, learning to build up a defense against the coronavirus, should it ever encounter it. But we don’t normally have mRNA encoding Spike protein floating around in our cells, so what happens to the mRNA itself after its injected into you and your cells make the bit of spike protein that tips off your immune system? “The mRNA from the vaccine is destroyed by the cell after the instructions are read,“ said Riordan.

snip

[triron]

8. Thanks. Science!

[Sogo]

12. Thank you for this article.

It puts to rest some of the conspiracy theories about the vaccinations.

[Happy Hoosier]

6. Much of life is about risk management.

COVID-19 is dangerous. We know this for sure.

And we know that not getting vaccinated has devastating economic and social consequences.

Preliminary evidence suggest the messenger RNA vaccines are safe. Probably extremely safe. But that isn't 100% certain.

Balancing those issues, the answer seems obvious to me:

Be exposed to actual, REAL risk now.... one with significant long term health risks, or even death,

OR

Be exposed to a potential risk, that many scientists think does not exist at all and if it does exist, it's implications are unknown. But so far, there is no evidence of ANY risk of that particular effect.

To me, this is a no brainer.

The people deciding against vaccination are like people who decide to drive instead of fly because they are afraid of an airline accident. It's just not a rational choice. It's one driven purely by emotion.

[BootinUp]

7. One could, theoretically, become

The monster of the deep lagoon.

ROFL.

[Claire Oh Nette]

9. Because he doesn't understand the difference between DNA and RNA?

"...the consequences of altered DNA, if any, are unknown. However, others, including the CDC said that the virus would not interact with DNA."

Of course, this is a much more confident and bold assertion, "Other scientists believe..."

But your brother certainly has more and better credentials than medical scientists an researchers and virologists and immunologists and bench chemists and Research pharmacologists, and middle school health teachers, yeah?

over 100,000,000 pfizer doses.
Another 80,000,000 moderna vaccines out there.
six extremely rare blood clotting events, out of over 7,000,000 J & J vaccines, for a .000004% of clots, but a 1 in 7 million chance of death.

All six women were pre menopausal and on birth control, which also carries a rare blood clot risk warning. It took just six for the CDC to say, whoa- what's this, and determine based on data and that J & J is not the vaccine for women ages 18-48. Good thing we have options.

But he should definitely not take it because he's not sure and doesn't trust the science. Fearful coward afraid of needles.

I'm going to start tweeting that the Pfizer vax is proving to enlarge small male members and opens up vasodilation to cure erectile dysfunction so even the most impotent phat phuck can sport a woodie. They've believe less plausible things, right?

[torius]

19. Only one was on hormonal birth control

according to WaPo. And the same thing happened to some men outside the USA. And that doctor in Florida died of the same condition after the Pfizer shot, but they were unable to conclusively tie to the shot. The condition mimics the natural condition so they left it as inconclusive.

[Claire Oh Nette]

21. They were all pre menopausal...

Women over 35 carry greater clotting risk with BCs, both progesterone and estrogen based pills. It's extremely rare, but it's there. I was part of the cohort who helped the CDC ascertain that with rare, estrogen connected women's heart attack when I was 24--spontaneous dissection. 80% of these MIs are female, average ave 42. Estrogen is the great protector in terms of cardiovascular disease, except when it isn't.

Observational and anecdotal, but enough to say this one is not the best choice for pre menopausal women. Correlation is not causation. But out of an abundance of caution, it's a pretty straight forward exclusion criteria for that particular vaccine.

I hand't seen that about the doctor and the Pfizer shot--just the one, or is there at least three to begin to establish a pattern?

The numbers of lethal adverse events is still miniscule for all the vaccines.

[torius]

25. interesting.

I read they think it was mostly women because most of the people getting it were health care workers who are mostly women, and that it also happened to a few men outside the US. I think they died of brain hemorrhage like the doctor, not of heart attacks. There's more info here, yes three people (the male doctor and two women, one age 72), and both Pfizer and Moderna so not 3 from a single one. But nothing conclusive, as it's possible to have a platelet condition with no symptoms. It's obviously very rare considering how many millions of shots have been given.
https://www.nytimes.com/2021/02/08/health/immune-thrombocytopenia-covid-vaccine-blood.html

[Claire Oh Nette]

30. It's a clotting thing...

a very rare cerebral sinus thrombosis.

The BC thing was connected to potential blood clots, too, since blood clots cause stroke and heart attacks. Seems in this small handful of people, may they rest in peace, the blood clot caused a cerebral hemorrhage, not a stroke.

The Pfizer and Moderna incidents don't quite fit the pattern--the age of the woman, and then the men.

Collective knowledge is the best we can do as we all learn about the virus and the vaccines as we go.

[hamsterjill]

33. They developed ITP

This is basically where the spleen mistakenly filters out platelets. My daughter had this as an adolescent. She is now in her thirties and has a normal count.

There is some thinking that the MMR vaccine might cause this for some children, and that thinking would coincide with the onset for my daughter. She received a booster before she was diagnosed with ITP.

She brought the article about the doctors death up to her own doctor before getting the COVID vaccine. He advised that she get vaccinated but that her platelets be monitored. This gave me great comfort. Going through the ITP situation was not something I’d want her to have to repeat. It was frightening and she was very lucky to have the outcome that she did. Grateful mom here!!!

[abqtommy]

10. I'd support any vaccine that could alter DNA to get rid of all the hate and leave love in

its place. That'd be wonderful!

[roamer65]

18. THIS.

[dweller]

11. Pass the genetically modified

veggie casserole, and the non-meat patties injected with chemical flavoring to make it look and taste like meat, enjoy your artificially sweetened beverage ...
shaddup and eat ...for dessert we have foot long aspartame popsicles but only IF
you get your COVID-19 vaccination first 😊

Bon appetit!

✌🏻

[hunter]

13. The vaccine carries a small fraction of the viral RNA.

An active infection carries ALL the viral RNA, infecting more and more cells, making more and more viruses in a chain reaction that doesn't stop until the patient's immune system defeats the virus or the patient dies.

Which is worse?

I'll have the vaccine, please.

In any case, human DNA is littered with the remains of past viral infections...

These fragments are the fossils of a number of ‘‘killer viruses’’, including several novel reassortments of influenza or coronaviruses that ravaged humans on a large scale in the past. These so-called endogeneous retroviruses (ERVs) are actually trophies of ancient molecular battles between viruses and their human hosts — one which the humans eventually won. “Some 8 per cent of human DNA represents fossil retroviral genomes,” pointed out Weiss in his seminal research paper in 2010.

https://www.telegraphindia.com/science-tech/the-human-dna-is-littered-with-fossils-of-viruses-past-that-attacked-us-and-lost/cid/1760295

(my emphasis)

[roamer65]

15. All the chemicals and radioactivity in our environment has done WAY more to alter our genes.

Rampant chemical polllution, radioactivity from nuclear testing and accidents is much larger worry than a mRNA vaccine.

Full meltdowns of 3 General Electric Mark I reactors in 2011 did us no favors, especially the one loaded with plutonium enriched MOX fuel.

Most people have used the fluoroquinone antibiotics like Ciprofloxacin, Avalox and Levaquin. The quinolones in those are KNOWN to interfere with DNA.

[ornotna]

17. It turned me into a newt

But I got better.

[MerryHolidays]

20. Jacques Monod was one of the first scientists to suggest the existence of mRNA

He won the Nobel Prize for Physiology/Medicine in 1965.

I won't get into the science of messenger RNA, which I perhaps once knew about in college, but mercifully have no clue about today. But Dr. Monod was also a spectacular intellect and coupled science with philosophy.

From his Wikipedia page, here are some pf his quotes that are remarkable in their scope:

"The first scientific postulate is the objectivity of nature: nature does not have any intention or goal."

"Anything found to be true of E. coli must also be true of elephants."

"The universe is not pregnant with life nor the biosphere with man. ... Man at last knows that he is alone in the unfeeling immensity of the universe, out of which he emerged only by chance. His destiny is nowhere spelled out, nor is his duty. The kingdom above or the darkness below: it is for him to choose."

https://en.wikipedia.org/wiki/Jacques_Monod

[Buckeye_Democrat]

22. If it wasn't this nonsense, it would be something else.

Like Republican viewers of Fox News... it gives them what they WANT to hear.

[jpak]

24. This is bullshit

Vaccine mRNA does not alter genomic DNA

Stop

[greenjar_01]

28. Posting a lot of misinformation here lately

[Leith]

29. For anyone who is concerned about this

please go to YouTube and search on this:

scishow mrna

The videos are short, informative, and interesting.

The point is that the mRNA in the vaccine does not have and does not interact with human DNA. The vaccine contains pieces of the messenger RNA and/or DNA that are particular to the virus only. It will not affect your cells or genetic material any more than the protein in your scrambled eggs will turn you slowly into a chicken.

[Buckeye_Democrat]

32. The RNA from those vaccines don't even...

... enter the nucleus of our cells, where our DNA is located.

Unlike the coronavirus and some other vaccines, such as J&J and AstraZeneca.

mRNA Vaccines
https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/mRNA.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fvaccines%2Fcovid-19%2Fhcp%2Fmrna-vaccine-basics.html
----------
Facts about COVID-19 mRNA Vaccines
They cannot give someone COVID-19.

mRNA vaccines do not use the live virus that causes COVID-19.
They do not affect or interact with our DNA in any way.

mRNA never enters the nucleus of the cell, which is where our DNA (genetic material) is kept.
The cell breaks down and gets rid of the mRNA soon after it is finished using the instructions.
----------


How the Johnson & Johnson Vaccine Works
https://www.nytimes.com/interactive/2020/health/johnson-johnson-covid-19-vaccine.html
----------
After the vaccine is injected into a person’s arm, the adenoviruses bump into cells and latch onto proteins on their surface. The cell engulfs the virus in a bubble and pulls it inside. Once inside, the adenovirus escapes from the bubble and travels to the nucleus, the chamber where the cell’s DNA is stored.
----------

[Klaralven]

38. There are reverse transcriptases that read RNA and produce the corresponding DNA

But in this case, the mRNA is outside the cell nucleus, and so would be any DNA so produced.

Thus, the chromosomes are unaffected.

[Spider Jerusalem]

34. Fun fact: about eight percent of the human genome is ancient viruses we've incorporated into our DNA

[Buns_of_Fire]

36. I haven't noticed any changes.

[krispos42]

37. No. Next question.

mRNA is how they duplicate the spike protein on the covid-19 virus.
Something about growing the DNA inside E. coli bacteria, then the mRNA is extracted and purified.

[Deminpenn]

39. Heard similar reasoning

from an anti-vax friend.

[dalton99a]

40. It is simply IMPOSSIBLE - the chances are exactly ZERO.