Hospitals testing nasal spray vaccine to combat Alzheimers

[packman]

Brigham and Women’s Hospital is in the early stages of testing a new nasal vaccine to fight Alzheimer’s disease, a neurological disorder that impacts the memory and mental function of more than 6 million Americans.

Romney center codirector Dr. Howard L. Weiner called the trial “a remarkable feat,” rooted in 20 years of research.

“If clinical trials in humans show that the vaccine is safe and effective, this could represent a nontoxic treatment for people with Alzheimer’s, and it could also be given early to help prevent Alzheimer’s in people at risk,” he added.
...
The vaccine harnesses the power of the immune system to eliminate beta-amyloid plaques — one of the hallmarks of Alzheimer’s. Experts, however, disagree on whether beta-amyloid plaques are connected to the cognitive decline that Alzheimer’s patients experience.
...
The experimental vaccine uses Protollin, an immune modulator made of proteins, to activate white blood cells found in lymph nodes on the sides and back of the neck. Those then travel to the brain and trigger clearance of the plaque, according to Tuesday’s announcement.

https://www.bostonglobe.com/2021/11/16/business/brigham-womens-hospital-is-testing-nasal-vaccine-alzheimers/

[3catwoman3]

1. May this be wildly successful.

That graphic with the gears drifting away is really grim.

[OhZone]

2. Oh, I hope this works!

I just hope beta-amyloid are a big part of the cause, and aren't important somewhere else!

You know?

[badhair77]

3. I pray this works. My mother and her siblings suffered with Alzheimer's.

I don’t think I have any symptoms as I seem to follow my father’s side. But I think about my brother and my son and whether they could be next. And such a simple thing as nasal spray. Amazing if it works.

[Duppers]

4. K & R

[electric_blue68]

5. So hope this works! ...

I did a quick look.

Beta-amyloid is found in the blood, and muscles, too. Seemingly in maybe regular form and not the kind of tangles found in the brain.
Don't quote me, tho, bc one headline said it may be a *whole body" problem which I've never heard before.
Like ...what... they get into the brain, and maybe the excess doesn't get flushed out?

My dad had "regular" dementia from a bleeding stroke and that was sad enough.

[LiberalArkie]

6. If that works, maybe they can make a drug that can dissolve the plaque in the arteries

[JanMichael]

7. Fingers crossed. Hope if it works that EVERYONE can benefit.

[Hekate]

8. KnR

[bigtree]

9. godspeed