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Thu Nov 25, 2021, 05:50 PM

Shocked... Shocked I tell ya'. Sputnik vaccine actually works better than Pfizer.

Let me start out by saying... I know people who've received Sputnik and in the back of my mind I always thought out loud "God I hope it's more effective than saline solution..."

Well hot damn. Independent Published Research Study out of the EU shows that Sputnik came in 2nd place overall and had the highest "Keeps you from dying" protection of ANY vaccine.

Oh and the AZ and the CinoVac... not so much.

https://www.bloomberg.com/news/articles/2021-11-25/moderna-edges-pfizer-in-hungarian-study-of-five-covid-vaccines

The Moderna Inc. and Russian Sputnik V Covid-19 vaccines both edged the version from Pfizer Inc. and BioNTech SE in effectiveness in a large-scale study of five different immunization shots conducted by Hungarian researchers.

Moderna’s vaccine was 88.7% effective in protecting against coronavirus infection and 93.6% effective against Covid-related mortality, compared with 85.7% and 95.4%, respectively for Sputnik, according to the paper published Wednesday on the website of the Clinical Microbiology and Infection medical journal. Pfizer came in third with 83.3% and 90.6%, respectively.

“The wide range of vaccines available in Hungary allows for the assessment of vaccine effectiveness in a real-world setting in a Central European country and puts Hungary in the unique position of providing detailed information on multiple vaccine types from the same country,” the authors, including Hungary’s minister in charge of health-care, Miklos Kasler, and chief medical officer Cecilia Muller, wrote in the study.

Here's the actual study:

https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X2100639-X/fulltext

21 replies, 1965 views

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Arrow 21 replies Author Time Post
Reply Shocked... Shocked I tell ya'. Sputnik vaccine actually works better than Pfizer. (Original post)
WarGamer Nov 25 OP
ProfessorGAC Nov 25 #1
WarGamer Nov 25 #3
ProfessorGAC Nov 25 #5
WarGamer Nov 25 #7
LisaL Nov 25 #8
ProfessorGAC Nov 25 #13
FSogol Nov 25 #2
WarGamer Nov 25 #4
Celerity Nov 25 #6
JohnSJ Nov 25 #9
WarGamer Nov 25 #10
JohnSJ Nov 25 #20
Monohull Nov 25 #11
StarryNite Nov 25 #12
Celerity Nov 25 #15
Monohull Nov 25 #16
Celerity Nov 25 #17
Raven123 Nov 25 #14
hamsterjill Nov 25 #18
roody Nov 25 #19
kimbutgar Nov 25 #21

Response to WarGamer (Original post)

Thu Nov 25, 2021, 05:57 PM

1. Surprises Me, Too!

Especially given these data from Worldometer.
I know we should be highly skeptical of their numbers early in the pandemic, but I'm equally skeptical that they've decided to report accurately now.
Their current daily case rate is the worst during the whole pandemic right now (around 40k cases per day). And, so are daily deaths. (Around 1,200)
Curious numbers considering they're mostly using the best vaccine.
https://www.worldometers.info/coronavirus/country/russia/

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Response to ProfessorGAC (Reply #1)

Thu Nov 25, 2021, 05:59 PM

3. I Know people there... VERY high anti-vax sentiment.

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Response to WarGamer (Reply #3)

Thu Nov 25, 2021, 06:04 PM

5. Certainly A Big Factor, But...

...it's not everybody and the numbers are worse now than ever, and Our World In Data shows them at roughly 30% fully vaxxed.
The numbers are still in conflict, because the antivax sentiment hasn't brought the vaxxed population to zero.
I have no reason to inherently distrust Hungarian researchers, but the numbers don't line up for me.

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Response to ProfessorGAC (Reply #5)

Thu Nov 25, 2021, 06:07 PM

7. One study doesn't tell the whole story but for now it's all we've got.

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Response to ProfessorGAC (Reply #1)

Thu Nov 25, 2021, 06:10 PM

8. Most of Russians are un-vaccinated.

In which case vaccine isn't going to help, is it? It doesn't work unless people are actually vaccinated with it.

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Response to LisaL (Reply #8)

Thu Nov 25, 2021, 06:50 PM

13. About 30% Fully Vaxxed

I looked it up.
30% is not "none" and their numbers are atrocious given the reported efficacy. It's a bit over 50 million fully vaxxed.

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Response to WarGamer (Original post)

Thu Nov 25, 2021, 05:59 PM

2. Sure, based on one Hungarian study.

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Response to FSogol (Reply #2)

Thu Nov 25, 2021, 06:00 PM

4. Peer reviewed... not exactly a Hungarian Doctor making shit up in his basement?

Until we have MANY studies... this is what we've got.

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Response to FSogol (Reply #2)

Thu Nov 25, 2021, 06:07 PM

6. Data from more than 3.7 million vaccinated people aged 16 and over were reviewed

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Response to WarGamer (Original post)

Thu Nov 25, 2021, 06:13 PM

9. Since they all above 80%, they are all good

Last edited Thu Nov 25, 2021, 09:15 PM - Edit history (1)

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Response to JohnSJ (Reply #9)

Thu Nov 25, 2021, 06:16 PM

10. yup. Moral of the story, get jabbed.

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Response to WarGamer (Reply #10)

Thu Nov 25, 2021, 09:16 PM

20. +++

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Response to WarGamer (Original post)

Thu Nov 25, 2021, 06:21 PM

11. Anyone know

 

if the J&J is ever going to be available for the under 16 year olds?

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Response to Monohull (Reply #11)

Thu Nov 25, 2021, 06:43 PM

12. I would love to know that too.

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Response to Monohull (Reply #11)

Thu Nov 25, 2021, 06:57 PM

15. Johnson & Johnson to study vaccine in younger adolescents this fall

https://spectrumlocalnews.com/nys/central-ny/news/2021/07/01/johnson-johnson-covid-vaccine-youth-kids-

Johnson & Johnson plans to begin a study of its single-dose COVID-19 vaccine in children as young as 12 years old by this fall, a spokesperson for the company said at a symposium hosted by Johns Hopkins University and the University of Washington on Wednesday.

Macaya Douoguih, head of clinical development and medical affairs for vaccines at Janssen, said the pharmaceutical company will use results from its Phase 2a trials — which tested the COVID-19 vaccine in a cohort of adolescents aged 16 and 17 — to inform its trial in the younger population.

“As we all know, the pandemic has had a profound impact on children and adolescents,” Douoguih said in part. “We are focused on the critical work needed to make our single-dose COVID-19 vaccine equitably accessible for all age groups.” Preliminary data from the Phase 2a study will be made publicly available in the near future, she added. The company currently has four adolescent studies planned, the first of which will consist of individuals aged 12-17 years old, which will kick off some time this fall.

Pending preliminary results from that study, Johnson & Johnson hopes to conduct two-part research in children aged 2-11 years old, starting with those aged 6 and up. A third study would test children aged 0-2 years old, with a fourth and final study looking at the vaccine’s efficacy in immunocompromised and high-risk children aged 1-17 years old. In total, the company expects upwards of 4,500 participants of all ages in the upcoming trials.

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Response to Celerity (Reply #15)

Thu Nov 25, 2021, 06:59 PM

16. Thanks for this.

 

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Response to Monohull (Reply #16)

Thu Nov 25, 2021, 07:07 PM

17. yw, sorry I could not find more up to date info via my somewhat cursory search

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Response to WarGamer (Original post)

Thu Nov 25, 2021, 06:53 PM

14. I wouldn't draw too many conclusions on comparative efficacy. They look good

The number of people who received Pfizer exceeds Sputnik, especially in the older population. I know the authors claimed to correct for age, but since the vaccines were not launched concomitantly, I wonder about how they were distributed.

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Response to WarGamer (Original post)

Thu Nov 25, 2021, 07:27 PM

18. Putin got it AND took an experimental nasal vaccine.

I am pulling for the nasal vaccines to become reality soon!

https://amp.cnn.com/cnn/2021/11/24/europe/putin-nasal-spray-covid-19-vaccine-intl/index.html

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Response to WarGamer (Original post)

Thu Nov 25, 2021, 07:59 PM

19. How do the Cuban ones

fare?

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Response to WarGamer (Original post)

Thu Nov 25, 2021, 10:54 PM

21. Sorry I don't believe anything coming out of Russia and I don't trust Putin

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