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Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region ForumsThe Complete Blood Count test shows how likely you are to get severe COVID-19 disease progression
Last edited Fri Dec 3, 2021, 11:26 PM - Edit history (1)
I had a CBC with Differential/Platelet done at LabCorp the other day and their reports now show a ratio, "Neut/Lymph Ratio," which is calculated by dividing your Neutrophils (Absolute) number by your Lymphs (Absolute) number. If the result is 0.0 to 2.9, studies suggest a LOW likelihood of severe COVID-19 disease progression. If the result is greater than 4.9, that indicates a HIGH likelihood of severe COVID-19 disease progression. FYI.
ETA:
Neutrophil-to-lymphocyte ratio, a critical predictor for assessment of disease severity in patients with COVID-19 https://pubmed.ncbi.nlm.nih.gov/33099889/
And a boatload of articles here: https://pubmed.ncbi.nlm.nih.gov/?term=neutrophil-to-lymphocyte+ratio+covid-19
tanyev
(42,541 posts)Sanity Claws
(21,846 posts)Do you have a link?
I did the math based on blood tests from April My ratio is 1.2.
ecstatic
(32,679 posts)Test - Current Result and Flag - Units - Reference Interval
Neutrophils (Absolute) - 0.9 Low - x10E3/uL - 1.4-7.0
Lymphs (Absolute) - 1.0 - x10E3/uL - 0.7-3.1
Neut/Lymph Ratio - 0.9 - ratio - 0.0-2.9
Published COVID-19 studies suggest:
Low likelihood of severe COVID-19
disease progression 0.0-2.9
High likelihood of severe COVID-19
disease progression >4.9
Pobeka
(4,999 posts)ecstatic
(32,679 posts)Neutrophil-to-lymphocyte ratio, a critical predictor for assessment of disease severity in patients with COVID-19 https://pubmed.ncbi.nlm.nih.gov/33099889/
And a boatload of articles here: https://pubmed.ncbi.nlm.nih.gov/?term=neutrophil-to-lymphocyte+ratio+covid-19
DrToast
(6,414 posts)Im surprised Ive never heard of this, but its fascinating.
marybourg
(12,611 posts)Dorian Gray
(13,490 posts)thank you for sharing.
Do you have access to any literature on the subject that I could read to further explain the phenomenon?
ecstatic
(32,679 posts)Disaffected
(4,554 posts)How could you ever get a result of 0.0 (or even close to that)? To get 0, your Neutrophils would have to be 0 and, your Lymphocytes could be any non-zero value.
Takket
(21,552 posts)They could have just said "less than or equal to 2.9" and it would mean the same thing.
Disaffected
(4,554 posts)and that is how it should be worded.
ecstatic
(32,679 posts)My adhd medication drives my neutrophils down pretty low, but it's sort of a pseudo-lowering because I haven't had so much as a common cold in at least 10 years.
I_UndergroundPanther
(12,463 posts)And I too haven't had a cold in forever.
Last thing I had with cold like symptoms was double pneumonia
I had a fever but forgot what a fever feels like.
So it was pretty bad when I finally realized I was seriously sick. The patient first place gave me an IV of antibiotics and told me if the symptoms got any worse
to go to the ER right away.
ecstatic
(32,679 posts)I'm glad you recovered. Even though I haven't had a cold or flu in 10 years, I assume that if I were to catch something, it would be really bad based on my low neutrophil count.
ARPad95
(1,671 posts)Neutrophil-to-lymphocyte ratio (NLR) has proven its prognostic value in cardiovascular diseases, infections, inflammatory diseases and in several types of cancers. However, no cut-off has been proposed on the basis of reference values coming from healthy population.
Conclusions
We have identified that the normal NLR values in an adult, non-geriatric, population in good health are between 0.78 and 3.53. These data will help to define the normal values of the NLR.
My NLR from my CBC in September is 1.399 (%) or 1.42 (Absolute?). I'm in my early 60s.
iemanja
(53,029 posts)You must have to ask for it to be run specially.
ARPad95
(1,671 posts)Neut
Lymp
%Neu
%Lym
At least that's how they're shown on my lab report. Then just divide the Neut # by the Lymp # to get the ratio.
iemanja
(53,029 posts)My test was CBC with platelet.
ecstatic
(32,679 posts)Update: I found out that the test MUST have differential in order to see the neutrophils and lymph counts.
CBC with differential. There are five kinds of white blood cells. The differential looks at how many of each kind of white blood cell you have.
Neutrophils: Help protect your body from infections by killing bacteria, fungi and foreign debris.
Lymphocytes: Consist of T cells, natural killer cells and B cells to protect against viral infections and produce proteins to help you fight infection (antibodies).
Eosinophils: Identify and destroy parasites, cancer cells and assists basophils with your allergic response.
Basophils: Produces an allergic response like coughing, sneezing or a runny nose.
Monocytes: Defend against infection by cleaning up damaged cells.
woodsprite
(11,910 posts)I did find my absolute lymph (1.6 no), but they only showed automated neutrophils (63%) so couldnt figure it out. This was a test from 11/12 while I was still doing chemo.
ecstatic
(32,679 posts)I think you can divide the percentage values too, but there's a very slight difference due to rounding.
woodsprite
(11,910 posts)albacore
(2,398 posts)I just had to get involved reading about this crap.... and I ain't all that bright.
What I think I read is that the NLR is a good predictor for all serious disease, not just Covid, and I think that a higher NLR means Covid will hit you harder than if you have a lower ratio.
I'm 78 and male with a cow valve in my heart and a pacemaker, so my NLR of 2.1 sounds good, comparatively.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5217256/
DrToast
(6,414 posts)Dont panic.
albacore
(2,398 posts)Maru Kitteh
(28,333 posts)I LOVE it!
ecstatic
(32,679 posts)I just had to share this info though.
NH Ethylene
(30,807 posts)retread
(3,761 posts)covid-19? How relevant are the conclusions to people without Covid?
ecstatic
(32,679 posts)but it definitely should be.
It looks like the neutrophils/lymphs ratio can be relevant to people without COVID based on previous studies that show how the NLR correlates with various diseases but from my understanding, there is no defined cut-off number for other conditions like there is for covid-19. ARPad95 links to a study about it in Post 8.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217256/
Sunsky
(1,737 posts)róisín_dubh
(11,791 posts)I had extremely mild covid in July despite being double vaxxed.