General Discussion
Related: Editorials & Other Articles, Issue Forums, Alliance Forums, Region Forums'I miss eating': the truth behind the weight loss drug that makes food repulsive
***snip***
Ozempic has become so popular in the last two years because it makes people lose weight fast. Its so controversial because of the way it works: by triggering a chemical repugnance to food itself. After being injected with Ozempic, a user could try to imagine a moist slab of black forest gateau, or a calorically-dense, half-pound Baconator bacon cheeseburger from Wendys, and their body physically revolts, with spasms of nausea and waves of ill feeling. Its the chemical realization of a behavioral psychologists wildest dream; A Clockwork Orange for junk food, an eating disorder in an injection.
On TikTok, videos documenting Ozempic-assisted weight loss have racked up hundreds of millions of views. Elsewhere on the internet, speculation that Ozempic has catalyzed the drastic body transformations of celebrities runs wild. A number of musicians and actors told the Guardian that they personally knew high-profile people in their industries using Ozempic, although none would go on record. Ghiyam has joined in on the publicity push himself, with his own informational #OzempicWeightLoss TikToks reeling in hundreds of thousands of views.
***snip***
Ozempic is also advertised regularly on TV: the ubiquitous commercials feature various characters who, having stabilized their blood sugar levels, are living healthy, active lives. Oh! they exclaim, turning to the camera, barely containing their excitement, as the soundtrack set to the earwormy melody of Magic, the breakout 1974 single by Scottish soft-rockers Pilot crescendos. Oh! Oh! Oh! Ozeeeeempic!
But the ad mentions weight loss only as an afterthought. In the motormouth recitation of precautions and potential side effects that underscore pharmaceutical ads, the voiceover says off-handedly You may lose weight! to which a chipper character responds, Oh!
***snip***
https://www.theguardian.com/food/2022/nov/09/i-miss-eating-weight-loss-drug-ozempic-food-repulsive
Personally? I'd do it in a heartbeat. My excess weight is probably my biggest health risk.
ETA: I despise those commercials, though!!!! They get stuck in my head!!!!!
Elessar Zappa
(16,385 posts)I love food and over consumption has been detrimental to my health.
TheBlackAdder
(29,981 posts).
You will literally not want to eat naturally after a couple of weeks.
The lack of simple and complex carbs reduces cravings, binges, insulin spikes, etc.
The 2-day fast is imperative to breaking the carb cycle that keeps spiking our desire to eat every few hours.
It's almost like prepping for a colonoscopy or the like, so it's doable. To jump start the 18-6 or 20-64 or OMAD (one meal a day) diet. Eat at dinner, sleep through the night, you're already 12 hours into your daily fast. Then, have coffee or breakfast and lunch to remove hunger pangs, and poof, you're at 2PM, which is the start of a 20-4 or 18-6 meal window.
.
Elessar Zappa
(16,385 posts)Ill give that a try.
doc03
(39,086 posts)a protein diet once. I lost weight for a couple weeks then hit a plateau. Then when I went off of it a few weeks later I gained it all back. A guy I worked with did the same and just kept losing weight even after quitting. He finally went to a doctor and found he had liver cancer. He was 340 when he started an 120 when he died three months later.
Hortensis
(58,785 posts)She and her husband, both aged but both slender and very physically active, decided they had put on some weight they wanted to lose. Like your coworker, she lost weight nicely with their diet -- which continued. Diagnosed with late-stage pancreatic cancer metastatic to liver and brain.
It was really their decades-long habit of treating illness with positive thinking and blowing off symptoms by working through them that was the problem. The relative risks of that course in youth and middle age had reversed dramatically in the 70s.
We all miss her a lot. One of those vibrant people who make everyone's life nice just by being there.
Genki Hikari
(1,766 posts)Not just the protein ones.
If you think livers look bad after a protein diet, don't look at what happens with a low-fat, high-carb diet. They're usually high in sugars of various kinds, because sugar is the only thing that can make low-fat foods palatable.
And sugar is what livers use to convert carbs into fat.
doc03
(39,086 posts)less calories. Those fad diets you get from charlatans like the ones Oprah promotes work for the short term. But they are
not good for your health long term.
Genki Hikari
(1,766 posts)Although lower-carb (not extreme low-carb) diets do work better, long-term, than other diets. Reducing sugar and high-carb foods like rice, pasta, bread and potatoes will help take weight off and keep it off. Plus, it's the one known way to keep diabetes at bay or under control. Eating lower-carb is as much a partner in how I keep my blood sugar from going crazy as exercise and insulin.
A lot of people think low carb means going crazy on meat and not eating vegetables, but that just isn't so. When I went low carb the first time, I actually ate more vegetables than I had before. Better vegetables, at that. Less corn and carrots. More spinach and zucchini.
Win/win.
patricia92243
(12,975 posts)Coventina
(29,731 posts)MaryMagdaline
(7,964 posts)The FDA has approved it for weight loss alone.
Genki Hikari
(1,766 posts)Insurance companies don't have to cover it for non-diabetic use. Or any drug.
A former insurance plan we had would NOT cover Nexium, for any reason. I was prescribed Nexium one week, and the next week, it went OTC. My old insurance plan still wouldn't approve it that one week before. They called it--kid you not--"experimental." I refused to pay for the prescription, because I heard it was going OTC. Cost a lot less OTC than it would have even if insurance had covered it.
So be careful out there, any non-diabetics wanting to take this med. You may have to pay a bigger portion of the costs for it than diabetics.
Genki Hikari
(1,766 posts)But also really--really--good insurance, because it's an expensive med. I think the typical six week supply is something like $1000. There is no generic, at least not yet.
I'm lucky in that my husband's company has super-good insurance, but it took a bit of a fight to get them to cover Ozempic, at least in the beginning. Most insurance plans always balk at covering it. Our insurance company won't cover non-diabetes Ozempic prescriptions at all, and I doubt that they're the only one. even the best insurance plans usually cover it only if you have a history of taking insulin and other diabetic meds. Otherwise, expect to foot a big portion of that $1000.
nolabear
(43,850 posts)He says he enjoys food fine but Its easier to push the plate away when youre full.
Im considering trying it but Im practically phobic about side effects, so havent decided yet.
rsdsharp
(12,002 posts)Blood sugar has been bouncing a little, but generally lower. Well see if the second injection does anything more. It is expensive, even with insurance.
Genki Hikari
(1,766 posts)In the beginning, I had a bit of food revulsion, but now I'm at the "easier to push the plate away" stage. Some foods, though, will definitely have me reach that stage sooner.
Avocado salsa, for instance. I used to be able to polish off half a jar with no problem. Now I can handle maybe the official serving size, and I'm done. If I use baked tofu strips as my "chips" then I'm lucky to get 2-3 bites down.
So it works...to an extent.
As for the side effects, eh, most people don't have anything other than blood sugar reduction and food suppression. When the ads list off all the potential side effects of meds, they have to mention if someone in the clinical trials got X or died while using it, even if there was only one person out of thousands tested who had that happen. Sometimes it's the med that caused the problem...and sometimes it's not. They still have to include it, though.
When you realize that many of the people in these clinical trials are not in the best of health to begin with (otherwise, why test on them?), it's not surprising that a few of them might have bad health outcomes while trying a new drug.
nolabear
(43,850 posts)Lord SAVE me from FB groups on health issues. I go in hoping for some actual info and even though I understand that people with no issues tend to be quiet there are some lines drawn between meds and symptoms that boggle the mind.
Genki Hikari
(1,766 posts)Had a World Lit assignment that required me to create a FB page for a character in an assigned story, and then post a "diary" following the plot.
I chose Isolde. Scheherezade was my preference, but sheesh, 1001 posts? No thanks!
As it is, I wouldn't trust anyone on FB to know their rear end from a hole in the ground. If I want medical advice to see if I need to go to an MD or not, I go to the Mayo or Cleveland Clinic websites. Or I ask my mom the retired RN.
Beyond that, when I have questions about my health care. I go to--brace yourself--one of the many doctors that my insurance and I are keeping afloat financially. Why am I paying these people, if not for their expertise? Sheesh. What a waste of money not to make them do some work!
nolabear
(43,850 posts)To his credit he goes to the pros. I dont follow internet stuff unless I do a ton of research to follow up.
DVRacer
(734 posts)On my diabetes and I had to play hell with the VA to prescribe it. I was told that possibly due to other drugs they gave me over the years I didnt produce insulin correctly anymore. In a single year my A1C went from 5.5 to 12.9 and would not come down. I saw the stupid commercials and asked if it was something we could try was told no it was too expensive. Took a year and Congressmen Mulletts VA representative to get it. I was told it cost the VA $4,000 a month for me, ridiculous and unaffordable for most. Now my number is falling now at 7.8 and slowly coming down a year later. I have lost 105lbs overall with the last 30lbs on Ozempic. I was 305 in 2015 now 198 my target weight is 175ish.
Coventina
(29,731 posts)MaryMagdaline
(7,964 posts)MaryMagdaline
(7,964 posts)I lost 50 pounds; no longer pre-diabetic; my brother lost 60 pounds and he is no longer pre-diabetic. Diabetes has decimated my family. One cousin died due to complications and my uncle lost his legs. My husband and father both developed heart disease because of diabetes. My husband died young (56) due to autoimmune disease (sarcoidosis) which likely resulted from diabetic complications. His brother died of diabetes at age 40. All my aunts and uncles (6 of them) on my fathers side had diabetes. I just might live 5 to 10 years longer if I avoid diabetes. Ive recommended ozempic to all of my extended family. One sister had side effects - nausea. I had mild side effects but great results using the lowest possible dose. My advice: drink lots of water. When using ozempic, your brain tells you that you are not hungry (great!) but it also tells you that you are not thirsty (bad!!). Drink water whether you want to or not.
Coventina
(29,731 posts)MaryMagdaline
(7,964 posts)MaryMagdaline
(7,964 posts)Weight loss had multiple positive effects.
uponit7771
(93,532 posts)Hekate
(100,133 posts)She says her brain is running really, really slowly these days, which makes phone calls and Zooms a little challenging. But shes lost weight ..
Remember Phen-fen? That stuff worked like a miracle for me. Sis and I compared notes: food only interested us 3 times a day while using it. Definitely a switch in the brain kind of thing.
Then the reports of heart damage in some people started to come out. As I say, oh dear.
I am the last person to judge another persons weight, and the first to say the issue is a lot more complicated than we know. Best of luck to us all, I say.
xmas74
(30,058 posts)I didn't need to lose much back then and looking back I shouldn't have had it. (I weighed 115 and wanted to weigh 100. No dr should have prescribed it to me but the 90s was about heroin chic.)
I had to force myself to eat on Phen Fen. All I wanted was black coffee, my Kool 100s and the occasional saltine or pink grapefruit, sometimes a mandarin. It was extremely unhealthy for me but I loved the results.
Genki Hikari
(1,766 posts)But the problem isn't usually as dire as anyone thinks.
The biggest thing that gets lost in translation: Even if ONE trial subject dies or has a heart attack while using the drug, the pharma company must include that death or cardiac problem in the potential side effects. Even if there's nothing that explicitly ties the death or heart attack or whatever to the drug.
Also keep in mind that the people selected for human trials are often not in the best of health, so it's not a surprise if some of the subjects die or otherwise have a bad health development that may or may not be related to the drug tested.
The trial reports to the FDA will show how many people were tested, how many of them died or whatever, and then it's about the math. Big PharmaCorp tested XYZ drug on 10,000 people and three people died during the drug trial? That means the death rate was 0.03% That isn't necessarily an indicator that XYZ drug will necessarily kill you. It only means that 3 someones died during the trial, and there's greater than even odds that it was coincidence rather than XYZ. Still, they have to list death as a potential side effect, to be on the safe side.
I'd be worried if I saw, say, 10% died of renal failure while taking XYZ. That means the drug is contraindicated for some discrete group of people, and the researchers will have to determine which group (over 65, diabetics on Ozempic, people with blue eyes--whatever) before getting FDA approval.
Or I'd worry if XYZ had a lot of contraindications of small percentages, but in a broader category of conditions. Let's say that 38 people of the 10K developed pulmonary hypertension. 53 had respiratory arrest. 197 got blood clots in the lungs. 244 got pneumonia. And so on. That's a sign that XYZ and the pulmonary system aren't playing well together, and thus something to be concerned about. Again, Big PharmaCorp will have to determine what's going on there before getting approval.
With the above contraindications, that's when the list of side effects will specifically say that people with X condition or taking Y medication shouldn't take XYZ without strict medical supervision. Or maybe not take it at all. It will depend on the drug and what it's designed to do.
The point is that the more specific the side effect listed, the more likely that it's something to heed.
Or that's how my mother the anesthetist explained it to me when I was leery of taking a prescribed drug after looking up the side effects. Turns out that the death side effect was over what I described: Some people in a clinical trial died, but it was a teeny tiny number. Not to belittle their deaths, but the number wasn't high enough for me to avoid a medication I needed at the time.
Dysfunctional
(452 posts)I went on a diet where I could eat just about anything I wanted but only between 4 and 5 PM. I went from 215 to 150 in 6 months. I am now at 160 because I started lifting weights 6 days a week alternating upper and lower body workouts 4 months ago. Not bad for 79 years old.
wishstar
(5,829 posts)My friend went from 245 to 180 by cutting calories in half (and eliminating most sugar) from about 2000 to 1000 calories per day and increased her walking, but nothing very strenuous and she also stayed very busy with her arts and crafts hobbies this year which helped with staying away from snacking.
I have had good luck with weight loss cutting back on eating after 3pm and upping my walking and bike rides but have found that the only way for me to stop the cravings is to eliminate sugar since that causes my blood sugar to spike and then fall.
Dysfunctional
(452 posts)That's one of the reasons why I work out.
uponit7771
(93,532 posts)... fat I'd be fine
Dysfunctional
(452 posts)If you don't want to spend a lot of money checking your body fat, use the navy body fat calculator. It is pretty accurate. All you have to do is put in your gender, age, weight, and size of your neck, waist, and hips if female. My body fat percentage went from 26% to 12%.
uponit7771
(93,532 posts)Dysfunctional
(452 posts)Also, work on your core. First go to an ear, nose, and throat doctor to check you out, an inner ear problem can cause a loss of balance. A physical therapist will show you some good exercises. If you can't afford a physical therapist some exercises that my physical therapist taught me. I am not a physical therapist but here are some exercises, place a band around your ankles and step to the side 5 steps and back doing 5 reps, tie the band to something solid and step back alternating legs, doing 5 reps, another one is standing at the bottom of your stairs and tap the next stair with one foot 5 times and alternate doing 5 reps. If that becomes easy see if you can step up 2 steps. This one is hard, get a balance plate and stand on it. Stand on one leg and walk toe to heel. Do not do any of these exercises unless you have someone who can hold you up if necessary usually holding you by your belt or having something stationary to hold on to. Do the farmer's carry, walk around carrying a weight, does not have to be heavy, in each hand for 2-3 minutes. If that is easy, carry a different weight, a 5-pound in one hand and a 10-pound in the other for 2 minutes, and then switch. Be very careful, you do not want to fall. I still can not jump rope.
uponit7771
(93,532 posts)woodsprite
(12,582 posts)To get their scripts filled! As a diabetic, that pisses me off royally! I also wonder what dose their drs are prescribing. I was on Trulicity (a close cousin to Ozempic), but it didnt make me nauseated at the thought of food, it just made me indifferent and feel satiety with a smaller amount (about half of what Id normally eat at a meal). Also, I didnt feel like snacking, and yes, I lost weight and my A1c came down to 6.4. I went off of it due to cancer treatment but would like to get back on it again. Also, only having to take 1 shot a week was awesome.
NickB79
(20,356 posts)She said it's a struggle to get enough of it for their diabetic patients.
Happy Hoosier
(9,535 posts)Type II Diabetes is caused by insulin resistance, but medicine is slow to catch up. It still largely treats diabetes as the disease when it is the symptom. We dont really screen for insulin resistance, but we should. More than 2/3 of fat people are also likely insulin resistant, so for those folks, treating the insulin resistance is likely to lead weight loss. Ozempic or other method of dietary changes can treat insulin resistance. The weight loss was s really a side effect.
davsand
(13,446 posts)I was on it for about a year. It absolutely curbs your appetite, and it is a self injected--painless, I swear--weekly shot. Unfortunately for me, it resulted in terrible constipation and I grew a couple masses in my thyroid. I had to have both nodules biopsied. Fortunately, neither one was cancerous. What a lot of people do not realize is that Ozempic does carry a black box warning about specific thyroid issues, and my experience is not as rare as docs might want to think. Ozempis is hella expensive, too.
I was taking it rather than Metformin because my system did not tolerate Metformin. Once my doc switched me to an extended release metformin I was able to get off "The O" and the nodules in my thyroid reduced in size.
I would never tell anybody not to take Ozempic, but I would encourage them to be sure and research the drug before you take it.
YMMV.
Laura
woodsprite
(12,582 posts)although it worked great for me. Since we knew I had active cancer in my body, they wanted me off it until I had surgery and was clear at least a year. This was a recurrence of endometrial cancer and definitely wasnt anything to do with the med.
hookaleft
(1,093 posts)WhiskeyGrinder
(26,955 posts)Coventina
(29,731 posts)WhiskeyGrinder
(26,955 posts)NickB79
(20,356 posts)Weight loss is the first recommendation to manage diabetes and prediabetes.
WhiskeyGrinder
(26,955 posts)symptom of diabetes, not a cause.
NickB79
(20,356 posts)WhiskeyGrinder
(26,955 posts)phylny
(8,818 posts)ironflange
(7,781 posts)The constant nausea made my life miserable; I may be unusually sensitive to it though. I don't take it any more, it just wasn't worth it.
MurrayDelph
(5,752 posts)but my Medicare Part D co-pay would be $500/month
Buckeye_Democrat
(15,526 posts)So that's good.
I've indeed lost some weight because of it (from 210 to 190 pounds), a side-effect of the chemo pills that I'm taking.
I recall someone proclaiming, years ago, that most of our sense of taste comes from our sense of smell. Well, that person was full of crap! He probably had a head cold and noticed that his sense of taste was diminished, but that's nothing like being unable to taste at all. My sense of smell is fine, by the way, so I can kind of weakly simulate tasting food as I breathe while chewing.
Edit: It's been gradual weight loss too, so I'd think a weight loss pill that temporarily caused loss of taste might be a better option. Not that such a thing has been invented, as far as I know, unless it was meant for something else like treating cancer.
My best culinary sensation during Thanksgiving was drinking some raspberry tea from my sister-in-law, because the raspberry was very aromatic.
TexasBushwhacker
(21,204 posts)My boss is obese and diabetic. He needs to lose weight in order to get a hip replacement. His wife is overweight but not obese. They've been getting Wegovy injections for about 6 weeks. They are both heavy drinkers.
There were some leftovers in the fridge that he was going to have for lunch. He has a hard time getting around, so I heated them up for him and took the container into his office. I went back 30 minutes latter to get the container off his desk and he had eaten 3 bites. He wants to eat psychologically, but just can't stand to eat more than a few bites.
dembotoz
(16,922 posts)Found a study that obese people would eat less if the food did not taste good.
It worked and bitter chocolate is a hell of a lot cheaper than ozempic.
decades later i still no longer crave that pastry.
Deep State Witch
(12,717 posts)Was pretty nasty on it's own. I would imagine that Ozempic is like Met on steroids.
I've lost almost 100 pounds on keto, but gained about 25 of it back in the last few months after having COVID. My A1C is like .1% point more than "normal". I've gotten off of all blood sugar and blood pressure meds.
Samrob
(4,298 posts)Zorro
(18,692 posts)grantcart
(53,061 posts)Twelve years ago I was diagnosed with diabetes and started with Metformin but quit when I had terrible cramps. I was able to control my blood sugar with diet exercise for 10 years but when I hit 65 needed help and my doctor put me on SLOW ACTING METFORMIN and that was much better for my stomach.
Now on Metformin, Trulicity, Insulin.
When you are a diabetic you are in a permanent science experiment, everyone's body reacts differently and your body will keep changing and you have to be flexible and on top of it.
If you don't find it coming together and getting it under control don't be afraid to change doctors to find one that is in sync with you.
Good luck.
LetMyPeopleVote
(179,869 posts)I am starting Trulicity soon. Both Ozempic and Trulicity are similar
https://www.google.com/search?q=ozempic+trulicity&sxsrf=ALiCzsYhL7rTJun7f36YCpKumn4ctvsS6A%3A1669442413267&source=hp&ei=bauBY7SkDJmkqtsPj4qa0AU&iflsig=AJiK0e8AAAAAY4G5fW3DwZhZ4ehNEqrPt1S9nJiYi-Jc&oq=ozempic+tru&gs_lcp=Cgdnd3Mtd2l6EAEYADIFCAAQgAQyBQgAEIAEMgUIABCABDIFCAAQgAQyBQgAEIAEMgUIABCABDIFCAAQgAQyBQgAEIAEMgUIABCABDIFCAAQgAQ6BwgjEOoCECc6BwguEOoCECc6BAgjECc6CwgAEIAEELEDEIMBOhEILhCABBCxAxCDARDHARDRAzoICAAQgAQQsQM6DgguEIAEELEDEMcBENEDOg4ILhCxAxCDARDlBBDUAjoKCC4QsQMQgwEQQzoHCAAQsQMQQzoECAAQQzoICC4QgAQQsQM6BAguEENQtQhYkC1ghUNoAXAAeACAAX2IAZkHkgEDOC4zmAEAoAEBsAEK&sclient=gws-wiz
Trulicity seems to have less side effects
I am at 6.3 AIC for the last year and a half on Victoza and so Trulicity may make more sense
grantcart
(53,061 posts)qualify are pretty liberal.
Great job on the 6.3
LetMyPeopleVote
(179,869 posts)It helps but you do have some diarrhea. I am taking a couple of OTC probiotics that seem to help with the diarrhea.
Genki Hikari
(1,766 posts)I was one of them. I lived a miserable existence on it, and even 20 feet from a bathroom was too far away to be. Multiple times a day. We're talking 7, 8 or more times a day.
Got switched to the Janumet. Slight improvement to 6-7 episodes, which was still too high. And then the problems started getting worse again. Got switched to Januvia + insulin + Ozempic. That took most of the edge off, but I was still having bad days, here and there. Going to an allergist found the last of the causes of my GI issues. One of them? After hearing about my experience with Metformin, my allergist included that in the test protocol. Turned out I was allergic to...Metformin. So I sort of came full circle there.
Anyway, after much trial and error, now I'm a happy camper.
phylny
(8,818 posts)I dont have any issues with either.
Joinfortmill
(21,165 posts)I had been taking glucosamine/chondroitin for over 20 years for joint pain. About three years ago the pain began increasing and spreading from my knees, to my hips and to my shoulders. I was doubling my dose and getting less pain relief.
Then I stumbled upon a youtube video of a guy who was talking about Moringa Leaf powder and how it reduced his arthritis pain considerably. I'd never heard of it. I did some research on it and learned it's a super food that has been used for centuries in India. The World Health Organization uses it to help populations in poor countries.
I took the capsules daily and within a couple of weeks my pain was completely gone. I've been completely pain free since. An unexpected side-effect was weight loss. I lost approximately 1.5 to 2.0 lbs per week until I'd lost 30 lbs. I've maintained the weight loss. Another interesting side effect was my desire for beef completely disappeared. I haven't had it since I began the Moringa. I eat much less meat overall. My blood work is excellent, as is my blood pressure. I'm 74 years old.
I highly recommend this super food for anyone's overall health. Do the research and try it. I'd get the capsules. The powder doesn't taste that great.
MaryMagdaline
(7,964 posts)Skittles
(171,715 posts)they ALL are detrimental
I think the reason people have such problems with weight is they are too sedentary.....
LetMyPeopleVote
(179,869 posts)I am type II diabetic with my diabetes under good control (6.3 AIC). I have been on Victoza for the las 12 or so years and my endocrinologist wants to change drugs. I will change over sometime next week when my last dose of Victoza is used up. I need to lose weight but my main concern is keeping the diabetes under control.
I will let you know how this works.
Genki Hikari
(1,766 posts)And it helps with reducing my blood sugar, combined with a bunch of other meds and of course diet and exercise.
I haven't had the loss of flavor, but I'm a supertaster, so I taste all kinds of crazy stuff in food that most people don't.
joshcryer
(62,536 posts)They basically found the cure for obesity in pill form. It's going to be the most prescribed drug ever when it gets through testing.
littlewolf
(3,813 posts)honest.abe
(9,238 posts)However she said is does work to lose weight.
Skittles
(171,715 posts)having your body feel spasms of nausea is NOT good
as with all these drugs, you can't just stop taking them when you think you've lost enough weight, you have to KEEP taking them.....