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SheltieLover

(80,311 posts)
Mon Jan 16, 2023, 08:33 AM Jan 2023

NEWS Stanford Study Reveals Secrets to Sustainable Weight Loss: Behaviors and Biomarkers Exposed

https://scitechdaily.com/stanford-study-reveals-secrets-to-sustainable-weight-loss-behaviors-and-biomarkers-exposed/

Stanford Medicine researchers have discovered biomarkers that can predict an individual’s ability to lose weight and maintain weight loss long-term. These biomarkers include signatures from the gut microbiome, proteins made by the human body, and levels of exhaled carbon dioxide. The study found that the bacteria in the gut and the amounts of certain proteins the body produces can impact an individual’s ability to sustain weight loss. Additionally, the research found that some individuals lose more weight on low-fat diets while others have better results on low-carb diets.

Strictly following a diet— either healthy low-carb or healthy low-fat — was what mattered for short-term weight loss during the first six months. But people who maintained long-term weight loss for a year ate the same number of calories as those who regained weight or who did not lose weight during the second six months.

According to the study, the bacteria living in your gut and the amounts of certain proteins your body makes can affect your ability to sustain weight loss. And some people, it turns out, shed more pounds on low-fat diets while others did better on low-carb diets.

Stanford Medicine researchers have identified several biomarkers that predict how successful an individual will be at losing weight and keeping it off long-term. These biomarkers include signatures from the gut microbiome, proteins made by the human body, and levels of exhaled carbon dioxide. The researchers published their findings on December 13 in the journal Cell Reports Medicine.

Much more at link. With pre-diabetes at such high levels, even for kids & young adults, this is likely a significant finding.
35 replies = new reply since forum marked as read
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NEWS Stanford Study Reveals Secrets to Sustainable Weight Loss: Behaviors and Biomarkers Exposed (Original Post) SheltieLover Jan 2023 OP
K & R malaise Jan 2023 #1
Glad you found if interesting! SheltieLover Jan 2023 #4
I've been 2 1/2 years on the keto lifestyle, not just a diet to lose weight, elocs Jan 2023 #2
Good for you! SheltieLover Jan 2023 #5
Yes, some people practice "dirty" keto which still works well for them. elocs Jan 2023 #8
Glad you were able go make the lifestyle change! SheltieLover Jan 2023 #9
It was fun, but alas, the zoo is gone now. elocs Jan 2023 #20
I lost over 100 lbs, and kept it off for over 2 years now, low carb, never miss a meal, never cheat Shanti Shanti Shanti Jan 2023 #14
Same here with Keto/Atkins Johnny2X2X Jan 2023 #15
Same here! Deep State Witch Jan 2023 #21
I'm glad to see serious scientific study of this problem cyclonefence Jan 2023 #3
Good for you! SheltieLover Jan 2023 #6
I had never heard of the respiratory quotient before. JanMichael Jan 2023 #7
I'd never heard of it either! SheltieLover Jan 2023 #10
None of us "need" to eat carbs since our bodies can make the carbs we need. elocs Jan 2023 #11
Read the book Breath by James Nestor- life changing Books_Tea_Alone Jan 2023 #12
Thx for sharing! SheltieLover Jan 2023 #26
I went with weight loss surgery. NutmegYankee Jan 2023 #13
Congratulations! highplainsdem Jan 2023 #18
Thanks! NutmegYankee Jan 2023 #19
Congrats! SheltieLover Jan 2023 #27
" the focus should be on eating high-quality foods that are unprocessed and low in refined flours an lindysalsagal Jan 2023 #16
Yes. Which means avoiding all those central aisles in most grocery stores and just highplainsdem Jan 2023 #17
You have more will power than I do. SheltieLover Jan 2023 #24
I really don't have willpower: It's chemical. If you can get off easy carbs for a week lindysalsagal Jan 2023 #28
Sadly, it didn't work that way for me. SheltieLover Jan 2023 #35
Great advice! SheltieLover Jan 2023 #23
Kickin' Faux pas Jan 2023 #22
Enjoy! SheltieLover Jan 2023 #25
It's Faux pas Jan 2023 #31
Glad you find it of interest. SheltieLover Jan 2023 #32
Hubby and I decided to do Mediterranean diet Tree Lady Jan 2023 #29
Healthcare provider suggested it to me SheltieLover Jan 2023 #30
I'll let you know Tree Lady Jan 2023 #33
Please do! SheltieLover Jan 2023 #34

SheltieLover

(80,311 posts)
4. Glad you found if interesting!
Mon Jan 16, 2023, 09:23 AM
Jan 2023

I'm fat, carb, & sugar restricted. What's left?

Yes' I cheat.

 

elocs

(24,486 posts)
2. I've been 2 1/2 years on the keto lifestyle, not just a diet to lose weight,
Mon Jan 16, 2023, 09:07 AM
Jan 2023

and at age 70 I lost 40 pounds in a few months and have kept it off ever since. I weigh now what I did in high school 52 years ago and I never count calories. Also, my health has improved because keto is highly anti-inflammatory and many of our afflictions and diseases are caused by inflammation.
Our so-called nutritional "experts" for the last 50 years have resulted in this nation having an obesity and diabetes epidemic, even in children.

SheltieLover

(80,311 posts)
5. Good for you!
Mon Jan 16, 2023, 09:25 AM
Jan 2023

I have a friend who did this. She goes off keto periodically, but has maintained her weight loss & feels terrific!

 

elocs

(24,486 posts)
8. Yes, some people practice "dirty" keto which still works well for them.
Mon Jan 16, 2023, 09:45 AM
Jan 2023

I am reminded of one of Obama's favorite sayings, "Don't let the perfect be the enemy of the good."

Keto is a dietary lifestyle choice and not a dogmatic dietary religion like both vegan and carnivore can be, opposite sides of the same coin with "thou shalt NEVER eat animal products!" and "thou shalt ONLY eat animal products!".

Keto has worked very well for me and it is my lifestyle, not just a diet. As a young man out of college I worked at my small city's zoo and our animals were on a diet, not to lose weight but what to feed them for optimal health. So keto is what I will be eating for the rest of my life.

SheltieLover

(80,311 posts)
9. Glad you were able go make the lifestyle change!
Mon Jan 16, 2023, 09:48 AM
Jan 2023

What a great experience to have worked at a zoo caring for the animals! (MotherNature's other kids.)

 

elocs

(24,486 posts)
20. It was fun, but alas, the zoo is gone now.
Mon Jan 16, 2023, 12:26 PM
Jan 2023

It's expensive for a small city to maintain a zoo properly, plus the state had minimum space requirements for the animals. Plus a good part of it had been built during the Great Depression. People howled when the zoo closed but would have howled louder had their taxes gone up to pay for it.
Had I stayed I could well have become the head of the zoo but also would have been the one to oversee its closing which would have been heartbreaking.

 

Shanti Shanti Shanti

(12,047 posts)
14. I lost over 100 lbs, and kept it off for over 2 years now, low carb, never miss a meal, never cheat
Mon Jan 16, 2023, 10:55 AM
Jan 2023

Started off keto too, changed everything about eating, now stay with more med/paleo diet, with lots of nonfat Greek yogurt, fresh fruit, nuts, berries, veggies, limited meat.

No cakes pies sweets refined sugar or flour, rice, pasta or starchy food, no fast food, none.

Never hungry but stop eating around 7pm, no food till 7am, 12 hr mini fast every day. Works for me. 5' 11, 165#. I'M 67.

All labs normal, last A1c 4.7, LDL 70, HDL 80. BP 120/70.

Oh yeah, home made smoothies and air fryer cooking and avocado toast with egg for breakfast most every day, yum

Johnny2X2X

(24,174 posts)
15. Same here with Keto/Atkins
Mon Jan 16, 2023, 11:00 AM
Jan 2023

Less 55 pounds during Covid and have kept it off. Went off it for a couple months during the Holidays, gained 15 pounds, am back on and that 15 is starting to come off.

All health numbers have improved. 50 years old, bp is perfect, cholesterol is normal. I have a resting heart rate in the 50s. Really is healthy for me.

Deep State Witch

(12,707 posts)
21. Same here!
Mon Jan 16, 2023, 01:22 PM
Jan 2023

Husband and I have been keto for 3 years now. I lost 99 pounds, but gained some of it back after COVID. He's lost about 50 and gained some of it back. Even so, we both feel healthier.

We do Keto Chow. We follow 2 Krazy Ketos and HungryHeath Parker on FB.

cyclonefence

(5,151 posts)
3. I'm glad to see serious scientific study of this problem
Mon Jan 16, 2023, 09:23 AM
Jan 2023

Overweight people go to the doctor and are told to follow a low-calorie diet. They may or may not lose weight. Too often, when/if they hit their goal weight they figure they're done with dieting, and it just doesn't work that way. You have to find a new way of eating and stick with it for the rest of your life.

Medical science has had nothing to offer the obese other than to tell them to lose weight. Maybe now this will change.

I know overweight women who have not been to the doctor in years because they don't want to be told how fat they are but getting no guidance in weight control. I think every doctor's office should have a big sign saying "You can refuse to be weighed."

I lost over a hundred pounds, on my own, seven years ago and have not regained any of it.

SheltieLover

(80,311 posts)
6. Good for you!
Mon Jan 16, 2023, 09:27 AM
Jan 2023

I've lost about 30 lbs & have regained a bit lately, but am right back to a more regimented lifestyle.

JanMichael

(25,725 posts)
7. I had never heard of the respiratory quotient before.
Mon Jan 16, 2023, 09:36 AM
Jan 2023

Wow. That could definitely be a game changer. I imagine it's not terribly difficult to calculate.

It's mainly because people have friends and say oh you can't eat any carbs or oh you can't eat any fat or oh you whatever.

It would be nice if somebody could take a test like that and just say hey I'm better on high carb or low fat.

Then toss in some exercise and don't sit so much and we may not use such bad health in the next 20 years.

First one I think it would be interesting for me. I work out a lot. About a 50-50 mix of cardio and resistance (ie bench squats deadlifts etcetera) training.

But I have no idea really whether low fat or high carb is best. I can bring my weight down to high school level while in good shape but it is a challenge and I have no idea of the carb fat preference of my body. That could be the difference in 5 or 10 lb of fat.

I have been taking in a literal truck load of fiber for last couple of years and I know that's been helpful.

SheltieLover

(80,311 posts)
10. I'd never heard of it either!
Mon Jan 16, 2023, 09:52 AM
Jan 2023

Kudos to scientists!

And to you for upping your fiber & maintaining a great workout routine.

I bought a treadmill & shortly afterwords developed drop foot. It's getting better slowly, but I'm not going to push it.

 

elocs

(24,486 posts)
11. None of us "need" to eat carbs since our bodies can make the carbs we need.
Mon Jan 16, 2023, 10:18 AM
Jan 2023

But we can see what a half century of nutritionists and their food pyramid of low fat/high carb has done for the health of this nation. I brought my weight down to high school level of 52 years ago easily and with no challenge. Body fat comes from excess carb consumption because what carbs your body cannot use for energy gets stored as...fat.

Books_Tea_Alone

(253 posts)
12. Read the book Breath by James Nestor- life changing
Mon Jan 16, 2023, 10:34 AM
Jan 2023

The book outlines how important carbon dioxide is in so many chronic conditions. Simple changes in breathing patterns can increase carbon dioxide in the body which has many health benefits. I've been doing it since last year and there are too many positive changes to list. These techniques go back thousands of years- really everyone should look up the studies outlined in the book

NutmegYankee

(16,477 posts)
13. I went with weight loss surgery.
Mon Jan 16, 2023, 10:44 AM
Jan 2023

Vertical Gastric Sleeve. It may sound drastic, but I was coming danger close to developing diabetes and needed a game changer. My primary care physician recommended this type of surgery and it was yielded spectacular results. I've lost over 115 lbs in the year since starting the program and went from 335 lbs to around 216 lbs. I should continue to lose weight for another 6-12 months, so I'm hoping to get below 200 lbs to be closer to my ideal weight for an average height male. I dropped from XXL or L, and lost 10 inches of waistline. I'll need to take daily vitamins for life, but I'm off of two of three blood pressure meds and likely about to drop the last one in the next month or two. I'm glad I did this - it is delightful to need much less food and I've lost most of my hunger. I appreciate studies like this as I can factor them into future weight maintenance efforts.

NutmegYankee

(16,477 posts)
19. Thanks!
Mon Jan 16, 2023, 12:02 PM
Jan 2023

It's been a wild year. It's weird to realize I'm thinner now than I was in high school.

lindysalsagal

(22,903 posts)
16. " the focus should be on eating high-quality foods that are unprocessed and low in refined flours an
Mon Jan 16, 2023, 11:25 AM
Jan 2023

and sugars." This I have found is my truth: If I stay off wheat and sugar, I'm less inclined to crave them and so I can keep to my calorie limits. Plus, they drive up your calorie, so, if you avoid them, you eat more food and still remain under the limits: i.e. fresh vegetables and broiled fish, etc.

highplainsdem

(61,991 posts)
17. Yes. Which means avoiding all those central aisles in most grocery stores and just
Mon Jan 16, 2023, 11:41 AM
Jan 2023

shopping around store's walls where you're most likely to find fresh produce, meat, fish and dairy (and avoid the bakeries: avoid most of the frozen foods as well).

I rarely buy anything except condiments and oatmeal from those center aisles.

I still crave sweets, or salty snacks, occasionally. But if I don't buy them, don't have them around, I can ignore the cravings, since they aren't worth a trip to the store, even though it's only minutes away.

lindysalsagal

(22,903 posts)
28. I really don't have willpower: It's chemical. If you can get off easy carbs for a week
Tue Jan 17, 2023, 09:36 AM
Jan 2023

the cravings go away. Your brain wants the easiest fuel, and that's carbs. So, if you lower them and make them more difficult to digest, like not wheat and sugar, your brain thinks, "oh! We moved! There isn't any wheat or sugar in this new land. I guess I want something else. " It's not morality: It's just fooling your brain and your chemistry.

Tree Lady

(13,269 posts)
29. Hubby and I decided to do Mediterranean diet
Tue Jan 17, 2023, 12:27 PM
Jan 2023

bought a huge cookbook for lots of choices. I have been trying to cut down on sugar and things made with flour but its hard.

I tried a meat, vege and some fruit with low carb but I am not a red meat fan, so think this diet will work better as sweets and dairy are in the low to rare category.

SheltieLover

(80,311 posts)
30. Healthcare provider suggested it to me
Tue Jan 17, 2023, 12:55 PM
Jan 2023

Looks like a tough one to follow.

Good for you, giving it a go!

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