Scientists think they found two key bacteria that cause multiple sclerosis

[Nittersing]

https://www.earth.com/news/scientists-think-they-found-two-key-bacteria-that-cause-multiple-sclerosis/

"For decades scientists have combed the gut looking for bacteria in the microbiome that push the immune system toward multiple sclerosis (MS). New evidence from a rare twin study now points a clear finger at two species of bacteria that hide in the small intestine.

The study, which compared 81 pairs of genetically identical siblings, singled out Eisenbergiella tayi and Lachnoclostridium as the most likely triggers of the nerve‑damaging disorder.

Dr. Anna Peters of Ludwig Maximilian University of Munich steered the international team that linked these bacteria to disease in both people and mice.

Tracing clues in identical twins
Identical twins share nearly every gene, so differences in health are often related to outside factors. By focusing on twins where only one sibling had MS, the researchers stripped away much genetic noise."

[ananda]

1. Wow. I really thought MS was genetic.

Wow

[radical noodle]

10. I did as well

Most of the people I know with MS had family members with MS.

[cannabis_flower]

11. It could be that it's partially genetic

But it takes the bacteria to trigger it.

[radical noodle]

26. It would be awesome to learn that's the case

I hope this turns into a cure eventually.

[soldierant]

21. Tes, but don't most families eat together, at least

for large chunks of their lives? I don't know how else these bacteria would get into the small intestine.

[radical noodle]

27. Not necessarily

The ones I knew were like cousins.

[womanofthehills]

17. Many believe environmental factors are involved

Many toxins (and viruses)
effect the central nervous system. Lots of autoimmune disorders out there now.

[TrollBuster9090]

18. I believe it has a genetic component, but there are other risk factors.

You inherit a certain combination of gene alleles, which gives you a genetic predisposition to develop MS. But what triggers it (ie-environmental factors) has long been a mystery. At one time they thought it was exposure to pesticides. Now it appears that having certain bacteria in your gut microbiome is a risk factor. And those bacteria got there as a result of what you've been eating.

Interesting stuff!
By the way, something that I always thought was funny regarding medical genetic research. Looking at sets of identical twins has always been the 'Holy grail' for these kinds of studies. If you have an identical twin, you'll be hounded by scientists for your entire life to volunteer for studies.

Another funny thing about medical genetic research is that Salt Lake City Utah was always the Mecca of genetic research. Mainly because the Mormons practiced polygamy. And, to avoid accidentally marrying your second cousin, the Mormons kept extremely detailed family trees (pedigrees). Those are great for identifying diseases with a genetic component. For all the trash talking people do about Mormons, we owe them a debt of gratitude. A huge chunk of what we know about diseases with genetic components came from the Mormons volunteering their family pedigrees for genetic research.

[ananda]

23. Thanks. My dad had an interesting RH factor anomaly.

Most of the time he was type O positive.

But every now and then it would shift to O negative.

When my younger sister was born, she had an RH
difficulty that completely baffled the doctors because
she was the sixth child and none of the ones before
her had it.

So they paid my dad to study his blood and that's
what they found.

Life can be very strange sometimes.

[harumph]

2. If this is accurate, amazing

[erronis]

3. This would be an incredible finding if their is a andidote to these bacteria.

So many people around the world are debilitated (and die) from this disease.

I imagine that other diseases would also be able to be traced to our guts (and skin/mouth/etc.).

[ClaudetteCC]

4. thanks for posting!

This is one of several articles I've seen just in the past few months highlighting the health importance of the makeup of ones intestinal microbiome

[electron_blue]

5. fascinating - but what about Epstein-Barr virus?

I thought it was caused by that - wasn't that in the news lately?

[eppur_se_muova]

6. Release the Epstein-Barr files ! nt

[Nittersing]

7. OK. That was funny.

[wolfie001]

12. Kind of sucks to have a last name that matches one the worst pedos

.....and tRUMP's closest BFF for 15 years.

[Hassin Bin Sober]

24. .

[angrychair]

8. Here lately, when they say "scientists found"

I know they mean scientists in other countries.
As is the case here.

It is not a mischaracterization to say that what is happening right now in the US-based scientific community is a literal apocalypse.

[wolfie001]

13. Piece of shit kennedy has set us back decades

Him and his stupid conspiracy cabal.

[mercuryblues]

9. Good. CAn we test them out on RFK Jr?

Maybe trump? Vance?

[BComplex]

14. In that case: Thank heaven for identical twins! This is great news!

So many people's lives could be restored if there was a cure for MS!

[ProfessorGAC]

15. Interesting

This definitely interests me as I've had MS for a bit over 30 years.
My recent scans appear identical to those from 2000. And, my condition at that point hadn't changed for a couple years.
I wonder if a natural or organic reduction in these two bacterial strains could explain a remission that has lasted over a quarter century.

[Nittersing]

22. Oh! That could be true, couldn't it?

Pretty exciting stuff.

[electric_blue68]

16. Wow, Good Luck and Keep Researching!

[TrollBuster9090]

19. I've been on DU for years, and this is definitely a FIRST! Thanks for the find!

1. I have MS in my family. My mother developed it when I was 14, and I've been dealing with it, one way or another, for the last 50 years.

2. I teach clinical microbiology and genetics. I'm always looking for good, interesting research papers to show to my students. I was even up last night looking for them on PUBMED. But I never IMAGINED that I'd find an interesting paper on DU! Thanks for finding that!!

[WestMichRad]

20. Terrific finding!

TY for posting this news.

[0rganism]

25. Very interesting, indeed. I've lived with MS for 15 years now, looks like this could really improve the situation

I hope this leads to a cure. My life might be basically over due to damage from this shitty disease, but younger patients could benefit radically. I'll talk with my neurologist about volunteering for treatment studies that emerge as a result. Thanks for posting!