Scientists have edited a gene that may reduce high cholesterol permanently

[Historic NY]

The study was extremely small — only 15 patients with severe disease — and was meant to test the safety of a new medication delivered by CRISPR-Cas9, a biological sort of scissor which cuts a targeted gene to modify or turn it on or off.

Preliminary results, however, showed nearly a 50% reduction in low-density lipoprotein, or LDL, the “bad” cholesterol which plays a major role in heart disease — the No.1 killer of adults in the United States and worldwide.



https://www.cnn.com/2025/11/08/health/cholesterol-gene-edit-wellness]

[Justice Brandeis]

1. No normal adult is ever going to have LDL of 40 or 50

The low 100's is far more realistic.

[womanofthehills]

4. Interesting- a Korean study in major Med journal (nature.com)

Of the entire population of Korea - study claimed “older” Koreans with cholesterol of 210 to 249 lived the longest. So many contradictions in this world!!! I’m sure there are studies with contradictions but being my cholesterol is 220 - I’m going with this one. 🙃.

“Total cholesterol and all-cause mortality by sex and age: a prospective cohort study among 12.8 million adults”

TC levels associated with lowest mortality were 210-249 mg/dL, except for men aged 18-34 years (180-219 mg/dL) and women aged 18-34 years (160-199 mg/dL) and 35-44 years (180-219 mg/dL). The inverse associations for TC < 200 mg/dL were stronger than the positive associations in the upper range.

https://www.nature.com/articles/s41598-018-38461-y

https://pubmed.ncbi.nlm.nih.gov/30733566/

[MyOwnPeace]

2. No doubt the tRump HHS department....

will cut funding for any research related to this. We can't have 'progress' in health care, can we............

[bluestarone]

3. Please keep this hidden, until TSF

is long gone!!