You know, this is a distinct possibility given the evidence:

[PCIntern]

Severe, Intolerable Fatigue Associated with Hyperresponse to Clopidogrel

Author links open overlay panel
David I. Bass Christopher C. Young Min S. Park Michael J. Cruz Kate T. Carroll Kevin N. Vanent Chungeun Lee Rajeev D. Sen Dominick J. Angiolillo 5, Marco Cattaneo 6, Louis J. Kim 1 7 8, Michael R. Levitt

https://doi.org/10.1016/j.wneu.2021.09.075

Objective
Clopidogrel is a commonly used antiplatelet agent for the prevention of thromboembolic complications following neuroendovascular procedures, but anecdotal data have raised concern for the possibility that clopidogrel may induce severe, intolerable fatigue. The purpose of this study is to systematically investigate this phenomenon.

***************
Conclusions
A syndrome of severe fatigue and other constitutional symptoms is a rare but clinically significant side effect of hyperresponse to clopidogrel in patients undergoing neuroendovasular intervention.


Kud bee……or similar meds prescribed for similar purposes. Several different types of hypertensive drugs, cause exhaustion, including beta blockers.

[CaliforniaPeggy]

1. Perhaps you're thinking that this drug might be causing him to fall asleep in meetings?

Could be.

[IcyPeas]

2. Would this make flying more dangerous for him?

[dweller]

3. Could this slow him down

To comatose ?
Room temperature?

🤔



✌🏻

[bucolic_frolic]

4. That's a possibility and a good fit

Lots of treatments cause fatigue. That "washed-out" feeling: IV chelation. Droopy confusion: Anti-psychotics.

[cachukis]

5. It appears they are doing what they can to keep him

in the game.

[tinrobot]

6. Neuroendovascular procedures? Minimally invasive brain surgery?

I'm surprised they found a brain.

Seriously, if he had brain surgery, that needs to be disclosed.

[Wounded Bear]

7. Not necessarily surgery. Been taking that drug since my TIA stroke...

Haven't had that symptom so far and it's been several months.

[PCIntern]

8. Happy to hear that about you personally...

It could be in combination with other medication he’s taking including beta blockers and who knows what else?

[Wounded Bear]

9. Indeed. Can't imagine all he's probably on to keep him upright...nt

[Prairie_Seagull]

22. I can speak to this personally.

I have contacted all of my docs about this and the response I get is, the fatigue is probably associated with something else. Like type 2 diabetes.

Without it however I am prone to significant TIA's. To the point where I really no longer go to the hospital. What would be another medication option?

I will be pointing to this study with a doc in near future.

[Gore1FL]

10. I've been on that since my AAA repair roughly 18 months ago.

I'm always tired, but assume it has to do with my poor sleep habits and outcomes.

[babylonsister]

11. He's old, tired, and his brain is failing him

obviously. I hope he finds peace soon!

[buzzycrumbhunger]

12. He was falling asleep in the courtroom ages ago, though

I suppose clopidogrel could be a factor, though in my time as a pharmacy tech, we dispense tons of this and I’ve never seen a patient with that complaint. I think it’s likely multifactorial, beginning with the fact he’s OLD, has fecal and urinary incompetence, the frontotemporal dementia, probable escalating tertiary syphilis, and has been popping Adderall and other crap as he pleases, eats McDonald’s garbage in huge quantities, yada, yada, yada.

I think it’s not unlikely that a new medication regime could indeed be one thing too many on top of all his other problems. If so, I vote that they double the dose and hurry him over the precipice.

[PCIntern]

16. It's common enough that they did study on it

And furthermore, who knows what else he’s on at this could be interacting with? Anything is possible, considering that he has possibly not had the best advice or necessarily heeds any competent physician’s advice.

[sakabatou]

13. Correlation doesn't equal causation

While his napping could be chalked up to his health, we shouldn't come to a hasty conclusion.

[PCIntern]

15. Guess what...

I can do anything I please. I can come to any conclusion I want given they feed us no information and there’s obviously a big problem. I can think he had a stroke, I can think he is on too many medications for his own good, I can think that they’re being implanted in his food by the CIA.

Ain’t no hasty conclusions here. I’ve been watching this sociopath for 40 years. Anything I say is valid as anything anybody else says and try to prove me wrong.

[llmart]

14. Can't be this.

He shows no "constitutional symptoms". He shits on our constitution every day.

[Swede]

17. Sleepness is also caused by staying up all night posting trolling bullshit.

[canetoad]

18. I wonder if

He has been told to stay off the Adderall (for health reasons).

[buzzycrumbhunger]

19. I think he's got so many comorbidities...

... that it might not be possible to blame one thing.

But hey, he's obviously getting worse so we all might have a happy Thanksgiving. Keep a good thought! 😉

[CTyankee]

20. That looks real bad! You'd think that idiot doc of his could do something about it.

What does this swelling indicate?

[Hugin]

21. Biff Spraytannen is mellowing like a...

Chemical toilet in the summer noon-day sun.