FDA Approves New Drug That Reverses Effects Of Narcan (satire)

Dec. 3, 2025
SILVER SPRING, MDPraising the drugs ability to quickly and effectively increase fatalities amongst the nations opioid users, the U.S. Food and Drug Administration approved a new nasal spray Wednesday capable of reversing the effects of Narcan.
The compound, called noroxone, was reportedly approved by the FDA as part of a broader effort to combat a surge in Narcan usage by vulnerable individuals who would have otherwise died. According to the manufacturer, the powerful opioid anti-antagonist is extremely fast-acting, and can re-depress the central nervous system and restore an overdose in just two to three minutes.
Narcan use in this country is a major public health concern for Americans, who are often left watching helplessly as friends and loved ones succumb to the resuscitating effects of emergency care, said FDA Commissioner Martin A. Makary, who called the drug an essential intervention in the global fight against harm reduction. Once sprayed into the nostril, noroxone works quickly to free up opioid receptors in the brain, allowing compounds like heroin, fentanyl, oxycodone, hydrocodone, codeine, and morphine to reattach and fatally interrupt respiration.
Noroxone, soon to be available both over-the-counter and as a prescription, was developed in response to what is widely known as the Narcan crisis, a nationwide epidemic that began in 2016 and has tragically saved hundreds of thousands of lives each year. Health officials praised the FDAs emergency authorization, which marks the first time an overdose reversal-reversal spray has been deemed effective and lethal enough to warrant widespread distribution.
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