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truedelphi

(32,324 posts)
Wed Dec 10, 2014, 06:26 PM Dec 2014

Whooping Cough's transmission is connected to the vaccine

This discussion thread was locked as off-topic by MerryBlooms (a host of the General Discussion forum).


Pertussis vaccine and transmission

http://www.ima.org.il/imaj/ar06may-2.pdf

Pertussis is considered an endemic disease, characterized by an epidemic every 2–5 years. This rate of exacerbations has not changed, even after the introduction of mass vaccination – a fact that indicates the efficacy of the vaccine in preventing the disease but not the transmission of the causative agent (B. pertussis) within the population [19].

_________________________________________________________________________________

http://www.cdc.gov/ncidod/eid/vol6no5/pdf/srugo.pdf

The effects of whole-cell pertussis vaccine wane after 5 to 10 years, and infection in a vaccinated person causes nonspecific symptoms (3-7). Vaccinated adolescents and adults may serve as reservoirs for silent infection and become potential transmitters to unprotected infants (3-11). The whole-cell vaccine for pertussis is protective only against clinical disease, not against infection (15-17). Therefore, even young, recently vaccinated children may serve as reservoirs and potential transmitters of infection.
###########################################

http://www.pnas.org/content/111/2/787

Proceedings of the National Academy of Science
"Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model,"
The study concluded that infant baboons given Sanofi DTaP (Daptacel) vaccine at two, four, and six months of age were protected against developing outward clinical symptoms of pertussis after being exposed to B. pertussis at seven months of age, but they were still able colonize and transmit B. pertussis to other baboons.

The baboons that were vaccinated with whole cell pertussis (GlaxoSmithKline's Infanrix) also colonized B. pertussis upon exposure to B. pertussis, but they cleared the infection much faster than the acellular pertussis vaccinated baboons—in 18 days compared to 35 days.

#####

To quote NVIC's Barbara Loe Fisher:

"In my opinion, this study in infant baboons suggests that pertussis vaccine-acquired immunity has been an illusion. Although the vaccines may protect against severe B. pertussis clinical symptoms of the disease—such as paroxysmal coughing—they do not prevent colonization of B. pertussis bacteria and transmission of the infection to others.

In this study at least, recovery from previous B. pertussis infection was more effective in preventing colonization with B.pertussis upon direct challenge than either whole cell DPT (Infanrix) or acellular DTaP (Daptacel) and that suggests transmission of the infection to others after exposure to B pertussis would also be less likely when there is a history of naturally acquired immunity."

My comment:
Fisher might be a little bit hard to folow, but what she is saying is that after a baboon has been infected with the WC anti bodies, the B. pertussis bacteria is then found in the lining of the throat. In a human being, the throat would perhaps be irritated and perhaps sore, but most significantly this person can then infect others with whooping cough.


Now, the researchers did not say that DTaP vaccine causes vaccine strain pertussis infection. B. pertussis vaccines (both whole cell DPT and acellular DTaP/Tdap) are inactivated vaccines and do not cause vaccine strain infection the way some attenuated live virus vaccines can—such as live oral polio (OPV) and varicella zoster (chickenpox) vaccines.

However, the lead author Tod Merkel did comment to the New York Times that when exposed to B. pertussis after recently getting vaccinated, you could be an asymptomatic carrier and infect others, saying:

"When you're newly vaccinated, you are an asymptomatic carrier, which is good for you, but not for the population."
17 replies = new reply since forum marked as read
Highlight: NoneDon't highlight anything 5 newestHighlight 5 most recent replies
Whooping Cough's transmission is connected to the vaccine (Original Post) truedelphi Dec 2014 OP
... SidDithers Dec 2014 #1
In a related note... Dr. Strange Dec 2014 #3
They are not which you cannot prove so stop saying that! KamaAina Dec 2014 #7
Wow, talk about needing to face palm! KitSileya Dec 2014 #4
Bullshit ... GeorgeGist Dec 2014 #2
To quote one of NVIC's other articles: KamaAina Dec 2014 #5
If you are exposed before the vaccine works, you can get the disease? Yes, but it isn't CAUSED by vx uppityperson Dec 2014 #6
Oh boy... greatauntoftriplets Dec 2014 #8
Great. I love it when DU is used for antivac idiocy. Warren Stupidity Dec 2014 #9
Scientifically speaking, this is on the same level as climate change denial. Hekate Dec 2014 #10
That is the dumbest thing I have read in quite a while. Liberal Veteran Dec 2014 #11
What makes this most depressing tammywammy Dec 2014 #12
What a crock of shit! longship Dec 2014 #13
Got my DPT vax in 1950 (?) HockeyMom Dec 2014 #14
Born in 1941. Every single child in my age group had the TDaP shot. Whatever was supposed to jwirr Dec 2014 #15
You should be ashamed of yourself. zappaman Dec 2014 #16
Locking. Host concensus- does not meet General Discussion SoP MerryBlooms Dec 2014 #17

SidDithers

(44,228 posts)
1. ...
Wed Dec 10, 2014, 06:28 PM
Dec 2014


Sid

Dr. Strange

(25,919 posts)
3. In a related note...
Wed Dec 10, 2014, 06:30 PM
Dec 2014

Jenny McCarthy and Robert Kennedy, Jr are the greatest doctors of our generation.

 

KamaAina

(78,249 posts)
7. They are not which you cannot prove so stop saying that!
Wed Dec 10, 2014, 06:33 PM
Dec 2014

Andrew Wakefield and Joseph Mercola are.

KitSileya

(4,035 posts)
4. Wow, talk about needing to face palm!
Wed Dec 10, 2014, 06:31 PM
Dec 2014

Anti-vaxx propaganda allowed on DU, what a low.

May the diseases they refuse to vaccinate against, only harm them and not the young, the weak, and those unable to vaccinate. If ever we needed justice in the form of Darwin awards, it is with anti-vaxxers and climate change deniers!

GeorgeGist

(25,318 posts)
2. Bullshit ...
Wed Dec 10, 2014, 06:29 PM
Dec 2014

Title.

Vaccine does not cause transmission.

 

KamaAina

(78,249 posts)
5. To quote one of NVIC's other articles:
Wed Dec 10, 2014, 06:32 PM
Dec 2014
http://www.nvic.org/NVIC-Vaccine-News/October-2014/Will-There-Be-An-Ebola-Outbreak-in-America-.aspx

Inquiring minds want to know the truth about why Ebola hemorrhagic fever has landed on American soil. Unfortunately, Congress and officials at the U.S. Department of Health and Human Services (DHHS), Departments of Defense (DOD) and Homeland Security are having a hard time coming up with answers that do not raise more questions.

Let’s review the brief timeline of what is being billed as “The Worst Ebola Outbreak Ever,” that has prompted top US public health officials to warn that Ebola could become as widespread as HIV/AIDS while pharmaceutical companies partnering with federal agencies are scrambling to fast track experimental Ebola vaccines to market....

That same day, the first NIH-developed experimental Ebola vaccine starts being tested on humans in several African nations while a U.S. public opinion poll reveals that the majority of Americans want a ban on incoming flights from Liberia and other countries where Ebola is rampant. By a 2 to 1 margin, Americans oppose sending American soldiers to those countries and 50% of Americans suspect there will be an Ebola outbreak in the U.S. ...

A logical conclusion is that some people in industry, government and the World Health Organization did not want the Ebola outbreak to be confined to several nations in Africa because that would fail to create a lucrative global market for mandated use of fast tracked Ebola vaccines by every one of the seven billion human beings living on this planet.


uppityperson

(115,677 posts)
6. If you are exposed before the vaccine works, you can get the disease? Yes, but it isn't CAUSED by vx
Wed Dec 10, 2014, 06:33 PM
Dec 2014

Well, yes. That is true for all vaccines.

For instance : If you have been exposed to influenza virus before getting the vaccine, or shortly thereafter before the vaccine works, yes, you can get influenza. Same with measles. And whooping cough.

Simply getting a vaccine does not mean at that point in time you are immune. It takes your body a bit of time to build up antibodies.

But no to your title. A viruses transmission is not connected to the vaccine, but to being exposed.

greatauntoftriplets

(175,731 posts)
8. Oh boy...
Wed Dec 10, 2014, 06:34 PM
Dec 2014
 

Warren Stupidity

(48,181 posts)
9. Great. I love it when DU is used for antivac idiocy.
Wed Dec 10, 2014, 06:42 PM
Dec 2014

Congratulations for propagating FUD. You do understand that babies will die because of antivac bullshit like this, right?

Hekate

(90,633 posts)
10. Scientifically speaking, this is on the same level as climate change denial.
Wed Dec 10, 2014, 06:44 PM
Dec 2014

Liberal Veteran

(22,239 posts)
11. That is the dumbest thing I have read in quite a while.
Wed Dec 10, 2014, 06:50 PM
Dec 2014

If I'm infectious when the needle went in, I'm probably infectious when the needle came out. The bizarre series of coincidences leading to me getting a vaccine for something I'm already contagious with is totally irrelevant. It doesn't make me more or less contagious.

tammywammy

(26,582 posts)
12. What makes this most depressing
Wed Dec 10, 2014, 06:52 PM
Dec 2014

Is that the anti-vaxxers aren't even embarrassed when spreading their bullshit around DU.

SMH

longship

(40,416 posts)
13. What a crock of shit!
Wed Dec 10, 2014, 07:17 PM
Dec 2014

Anti-vaccination lunacy.

 

HockeyMom

(14,337 posts)
14. Got my DPT vax in 1950 (?)
Wed Dec 10, 2014, 07:20 PM
Dec 2014

If you think I am going to run out and get a booster after 60+ years, you are out out your mind. I am sure I am not alone among my generation. Do you people seriously think I care about "Dr. Jenny" who could be my CHILD?

I could say what I think about your vax, but I won't. I am not a CHILD, and neither are MY children.

jwirr

(39,215 posts)
15. Born in 1941. Every single child in my age group had the TDaP shot. Whatever was supposed to
Wed Dec 10, 2014, 07:30 PM
Dec 2014

happen to us did not seem to show up. What is it I am supposed to have because I was one of the millions who had the shot?

zappaman

(20,606 posts)
16. You should be ashamed of yourself.
Wed Dec 10, 2014, 07:56 PM
Dec 2014

But I don't think you are.
Sad.
Kicking so more people can see your sad OP and maybe learn how it is COMPLETELY full of shit.

MerryBlooms

(11,761 posts)
17. Locking. Host concensus- does not meet General Discussion SoP
Wed Dec 10, 2014, 07:56 PM
Dec 2014

Please consider the Creative Speculation (Group)-
http://www.democraticunderground.com/?com=about&forum=1135

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