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Native

(7,349 posts)
Thu Aug 4, 2016, 01:38 PM Aug 2016

NIH Plans To Lift Ban On Research Funds For Part-Human, Part-Animal Embryos

Source: NPR

The federal government announced plans Thursday to lift a moratorium on funding of certain controversial experiments that use human stem cells to create animal embryos that are partly human.

The National Institutes of Health is proposing a new policy to permit scientists to get federal money to make embryos, known as chimeras, under certain carefully monitored conditions.

Read more: http://www.npr.org/sections/health-shots/2016/08/04/488387729/nih-plans-to-lift-ban-on-research-funds-for-part-human-part-animal-embryos



And so it begins.
49 replies = new reply since forum marked as read
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NIH Plans To Lift Ban On Research Funds For Part-Human, Part-Animal Embryos (Original Post) Native Aug 2016 OP
Are we going to call them manimals? christx30 Aug 2016 #1
How many more Republicans do we need??!! misterhighwasted Aug 2016 #2
Ha, good one. mountain grammy Aug 2016 #4
It's all about coulda, and not about shoulda... sweetloukillbot Aug 2016 #3
...and here I actually though THAT theory was bunk. Shandris Aug 2016 #5
I remember reading about this research in the 80's, so it started long ago. pnwmom Aug 2016 #9
OH my....I think I'm going to be ill. Shandris Aug 2016 #12
If man could be crossed with the cat it would improve man, but it would deteriorate the cat. niyad Aug 2016 #6
+ a million. misterhighwasted Aug 2016 #7
Sayeth the cat. JudyM Aug 2016 #35
The fundies will likely blow their tops over this. Buckeye_Democrat Aug 2016 #8
There are many thoughtful non-fundies with concerns about this. pnwmom Aug 2016 #17
As long as we put the military in charge of the creations Buckeye_Democrat Aug 2016 #19
I think this is one of the many ethical issues that is complicated and not black and white. pnwmom Aug 2016 #21
I agree Buckeye_Democrat Aug 2016 #23
And those with few morals will find it totally acceptable. R. Daneel Olivaw Aug 2016 #26
I'm reserving judgment for now Buckeye_Democrat Aug 2016 #28
I look through the lens of human / corporate arrogance. R. Daneel Olivaw Aug 2016 #29
My focus is science and understanding Buckeye_Democrat Aug 2016 #30
What happens when humanity creates a hybrid creature R. Daneel Olivaw Aug 2016 #39
The article indicates Buckeye_Democrat Aug 2016 #41
Point taken, but scientists are employed by...? R. Daneel Olivaw Aug 2016 #44
I understand Buckeye_Democrat Aug 2016 #47
However, if something can be done, it will be done regardless LanternWaste Aug 2016 #46
This is great news for the furry community snooper2 Aug 2016 #10
Finally. Disney will be able to create more human/animal hybrids like Mickey and Goofy. Kablooie Aug 2016 #11
Not to mention Nick and Judy. Archae Aug 2016 #38
I knew you guys would have a blast with this! Native Aug 2016 #13
I think many people would be uncomfortable with that, myself included. pnwmom Aug 2016 #14
Agreed. R. Daneel Olivaw Aug 2016 #27
I'm against it SharonClark Aug 2016 #45
And so it starts... uawchild Aug 2016 #15
But, but only under "carefully monitored conditions"! Native Aug 2016 #18
Yes, the possibilities can make you shudder. JudyM Aug 2016 #36
I don't know how I feel about this. mountain grammy Aug 2016 #16
Awesome Renew Deal Aug 2016 #20
Still would actually be an improvement for him from having the horses ass in the front. nt cstanleytech Aug 2016 #22
bookmarked for later elehhhhna Aug 2016 #24
The photo seems incomplete - Sunriser13 Aug 2016 #31
DUzy! meow2u3 Aug 2016 #33
I was going to make a post about centaurs... awoke_in_2003 Aug 2016 #34
Pigoons for everybody! R. Daneel Olivaw Aug 2016 #25
Eat your vegetables! I am. Tastes like beef, chicken, pork and planimal. yumm. eom Festivito Aug 2016 #32
So they develop an animal with a human brain. And a corporation will have far more rights. JudyM Aug 2016 #37
Monsanto needs to make more Republicans harun Aug 2016 #40
Paging Dr. Moreau trof Aug 2016 #42
I want wings to fly over all the bullshit. GOLGO 13 Aug 2016 #43
Trollocs! Nt Turin_C3PO Aug 2016 #48
Old news. randome Aug 2016 #49

christx30

(6,241 posts)
1. Are we going to call them manimals?
Thu Aug 4, 2016, 01:47 PM
Aug 2016

Please tell me they're going to be called manimals. That would just make my day when I'm getting my crossbow ready to defend my family.
But I for one, welcome our new overlords, and hope they rule with an even hand.

 

Shandris

(3,447 posts)
12. OH my....I think I'm going to be ill.
Thu Aug 4, 2016, 02:05 PM
Aug 2016

Thank you for the article though; I had somehow overlooked that, and as I heard that odd theory I was like 'yeah, nah, too out there'. Woah.

Puts Thundercats in a whole new light, that's for damn sure. 0.0

niyad

(132,113 posts)
6. If man could be crossed with the cat it would improve man, but it would deteriorate the cat.
Thu Aug 4, 2016, 01:57 PM
Aug 2016

mark twain

the full quote:

Of all God's creatures there is only one that cannot be made the slave of the lash. That one is the cat. If man could be crossed with the cat it would improve man, but it would deteriorate the cat.
- Notebook, 1894

Buckeye_Democrat

(15,526 posts)
8. The fundies will likely blow their tops over this.
Thu Aug 4, 2016, 02:02 PM
Aug 2016

Oh, well.

Cross humans with cyanobacteria to make them photosynthetic. Then we'll have a true Green Party.

Buckeye_Democrat

(15,526 posts)
19. As long as we put the military in charge of the creations
Thu Aug 4, 2016, 02:17 PM
Aug 2016

... we should be okay.

Like nuclear weapons.

JOKING!

I would need to read more about possible benefits before passing judgment. I have a rare condition that causes blindness (already blind in one eye). It's not nearly the same thing as creating chimeras, but mice that had their genetic code altered to cause the same problems have helped researchers understand the disease better.

pnwmom

(110,254 posts)
21. I think this is one of the many ethical issues that is complicated and not black and white.
Thu Aug 4, 2016, 02:22 PM
Aug 2016

So I wouldn't reject this out of hand.

However, years ago I was on a committee that reviewed University research and was surprised about the casual attitude of some of the researchers. They proposed using sperm from a sperm bank without getting permission from the donors for this use. That didn't seem right to me -- but a couple scientists on the committee thought it would be fine. I don't remember what the final decision was, but it still seems wrong to use donated sperm in this manner without getting permission.

Buckeye_Democrat

(15,526 posts)
23. I agree
Thu Aug 4, 2016, 02:29 PM
Aug 2016

Unless the donors are aware or signed off on any use of the sperm (or eggs for women), that shouldn't be done.

As humans, we have contracts with each other.

I don't like any research that causes pain and suffering either, although I obviously made a concession on the mice that go blind by having a gene altered -- same as the human one that's defective in my case. It's not like it HURTS, though, and the mice are fed and looked after.

Buckeye_Democrat

(15,526 posts)
30. My focus is science and understanding
Thu Aug 4, 2016, 03:14 PM
Aug 2016

... with a wary eye on human and corporate arrogance.

Science is behind almost all of the wealth of humanity, although most scientists don't benefit from it compared to businessmen/corporations.

I'm thankful for insecticides and government programs that prevent mosquitoes from making life miserable and more deadly in populated urban areas, among many other things.

I don't like to see sentient creatures suffer, and we should be cautious in that regard.

 

R. Daneel Olivaw

(12,606 posts)
39. What happens when humanity creates a hybrid creature
Fri Aug 5, 2016, 08:59 AM
Aug 2016

with its own identity and sentience?

Does humanity have the right to own it, imprison it, enslave it and erase it at will?

Humanity is full of stories of human cruelty and ignorance.

Just because something can bedone does not mean it should be done.

Mosquito control is one thing. But hybridization?

Buckeye_Democrat

(15,526 posts)
41. The article indicates
Fri Aug 5, 2016, 09:10 AM
Aug 2016

... restrictions on brain research that could cause such a thing.

I admit that, based on my personal interactions, I probably place more faith in scientists and their judgments than most people. I personally wish they'd be in charge of our nuclear arsenal rather than some potential nitwit President.

EDIT: And if there was ever a viable "Science Party" in this country, I'd probably join it. As of now, most scientists are overwhelmingly Democrats and independents.
http://www.slate.com/articles/health_and_science/science/2010/12/lab_politics.html

A Pew Research Center Poll from July 2009 showed that only around 6 percent of U.S. scientists are Republicans; 55 percent are Democrats, 32 percent are independent, and the rest "don't know" their affiliation.

Buckeye_Democrat

(15,526 posts)
47. I understand
Sat Aug 6, 2016, 05:20 AM
Aug 2016

I have a rare genetic condition that causes early blindness. I went blind in one eye already.

I started experiencing distortions in the other eye about two years later, an indicator that blindness would soon follow.

My ophthalmologist suggested an experimental drug that had shown great success, and I signed a legal waiver to have it injected in my eyeball. It worked! The distortions went away and blindness was thwarted until the next time that distortions were observed. I've received about 25 injections over the last 10 years, and I still have my eyesight in one eye. I would otherwise be disabled, unable to drive and most likely receiving government disability for blindness.

The drug is called Avastin. It was developed by scientists at Genentech to treat colon cancer. For those patients, it's injected into their bloodstream from IV bags. It's not a very effective treatment for colon cancer compared to others, so there's many times that hospitals don't use those IV bags at all. Based on how it works on cancer cells, ophthalmologists in Florida decided to try the drug to treat patients experiencing similar problems to mine. It proved extremely effective, and word spread of this wonderful eye treatment.

I started to go into lengthy details, but I deleted it. I'll just cut to the chase and tell you that, a few years ago, the owners of Genentech decided to be greedy and tried to make it illegal for ophthalmologists to divide those unused IV bags of Avastin. They claimed that they were "concerned" about the drug being contaminated during the division into smaller samples, and they wanted exclusive rights to sell the smaller samples under the name Lucentis for much higher cost. Instead of me paying $300 per injection, it was going to cost me about $2500 per injection under their proposal! Insurance would not help pay for it because Genentech didn't include people like me in the FDA study for Lucentis.

Thankfully, ophthalmologists all over the country raised a big stink about it and Genentech finally backed off. I feel confident that several scientists at Genentech were probably opposed to the greed as well, although I never heard any public statements from them (which would probably cost them their jobs).

Now that I've shared that, I'll just say that I ultimately think there's something fundamentally wrong with how legal contracts are written in this country. I'm not a lawyer, but I've observed many cases over the years when certain people become quite wealthy simply because they have a contract that gives them "ownership" of ideas and technology. I understand the basic idea behind patents and other contracts to reward people for their intellectual work, but it's reached the point where the intellectuals are given scraps for their work while business parasites reap the biggest rewards.

Even Bill Gates, who I appreciate in many ways for his philanthropic work, mostly became insanely wealthy due to legal contracts. He didn't develop DOS himself. He purchased it (and thus had legal ownership). He then used another contract with IBM to essentially have an early monopoly in computer software. I don't think it's a coincidence that Bill's father was a lawyer. By the way, I saw Bill Gates participating in a computer trivia contest many years ago, and I did better than him at answering the questions! I majored in math & physics, not computer science!

It;s ultimately how contracts are written (and enforced by our government) that causes many issues.

Back to the human-animal chimera issue... nobody is yet developing them to term. As of now, studies are underway to observe the fetuses to see if there's any unwanted results... such as the human stem cells interacting with the animal's brain and nervous system. The early results have apparently been promising. The animals have their genes altered to prevent them from forming a particular organ, and the human stem cells seem to only help form those organs. Without further study, scientists can't even be sure that ethical concerns are warranted. (Except from the same kinds of people who believe in souls and likely opposed human to human organ transplants as well.)

 

LanternWaste

(37,748 posts)
46. However, if something can be done, it will be done regardless
Fri Aug 5, 2016, 03:05 PM
Aug 2016

"Just because something can bedone does not mean it should be done..."

However, if something can be done, it will be done regardless of whether it should be done or not, regardless of ethical concerns and regardless of potential for abuse. Science as practiced by humans has both aptly and accurately illustrated this to us time and time again.

SharonClark

(10,497 posts)
45. I'm against it
Fri Aug 5, 2016, 12:46 PM
Aug 2016

Humans have a long history of exploiting animals for greed, self-aggrandizement, and bogus medical research. What would be accomplished that could warrant something as ethically-challenged as hybridization?

uawchild

(2,208 posts)
15. And so it starts...
Thu Aug 4, 2016, 02:07 PM
Aug 2016

What a slippery slope. I can imagine all sorts of dystopian applications in the not so distant future.

Murphy's Law applied to genetic engineering is scary.

Native

(7,349 posts)
18. But, but only under "carefully monitored conditions"!
Thu Aug 4, 2016, 02:14 PM
Aug 2016

I thought that was the scariest part of the article.

mountain grammy

(29,003 posts)
16. I don't know how I feel about this.
Thu Aug 4, 2016, 02:07 PM
Aug 2016

It sounds kind of creepy and a what could possibly go wrong scenario, but then, it could lead to great discoveries.

cstanleytech

(28,454 posts)
22. Still would actually be an improvement for him from having the horses ass in the front. nt
Thu Aug 4, 2016, 02:22 PM
Aug 2016

Sunriser13

(612 posts)
31. The photo seems incomplete -
Thu Aug 4, 2016, 03:51 PM
Aug 2016

- a certain Cheeto's head isn't hanging out the patootie of the Putin-centaur spitting out little yellow Cheeto piles...


JudyM

(29,785 posts)
37. So they develop an animal with a human brain. And a corporation will have far more rights.
Thu Aug 4, 2016, 05:24 PM
Aug 2016
 

randome

(34,845 posts)
49. Old news.
Sat Aug 6, 2016, 09:42 PM
Aug 2016


On the other hand...topless women centaurs! Yes!
[hr][font color="blue"][center]A ton of bricks, a ton of feathers, it's still gonna hurt.[/center][/font][hr]
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