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Thu Mar 12, 2020, 05:22 PM

Desert_Leslie (131 posts)

South Korea experts recommend anti-HIV, anti-malaria drugs for COVID-19

Source: United Press International

March 12 (UPI) -- South Korean disease experts have begun to recommend the use of a combination of antiviral and anti-malaria drugs for patients of the new strain of coronavirus.

Kwon Jun-wook, deputy head of the Korea Centers for Disease Control and Prevention, said Thursday at a regular press briefing the recommendations come from multiple groups, and that the government is ready to apply the recommendations to patients "where necessary," Newsis reported.

The groups advised discretion among medical professionals, while recommending the administration of Kaletra, an anti-HIV medication that includes the drugs lopinavir and ritonavir. Kaletra blocks the ability of HIV to replicate itself, and also inhibits the growth of cancer cells.

South Korean experts are also recommending the use of hydroxychloroquine in combination with the anti-HIV medication. HCQ is sold under the brand name Plaquenil, among others, and is used for the prevention and treatment of malaria.

Read more: https://www.upi.com/Top_News/World-News/2020/03/12/South-Korea-experts-recommend-anti-HIV-anti-malaria-drugs-for-COVID-19/6961584012321/

DUers, I am not a medical professional -- but this is good news, I hope.

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20 replies	Author	Time	Post
South Korea experts recommend anti-HIV, anti-malaria drugs for COVID-19 (Original post)	Desert_Leslie	Mar 2020	OP
Why not?! It looks as if it calls for a cocktail of viral drugs. I'm glad they feel they could help.	ancianita	Mar 2020	#1
"Anti viral drugs"	Pachamama	Mar 2020	#3
Unless those Meds are imported from China	at140	Mar 2020	#2
Every dim watted twit head is gonna panic now, hearing only HIV...	dixiegrrrrl	Mar 2020	#4
Yep...	flying rabbit	Mar 2020	#7
But trumpie knows more than these guys, so	louis-t	Mar 2020	#5
Just contacted my PCP doc and gave staff this website link. She says thank you.	sprinkleeninow	Mar 2020	#6
Me Too	Desert_Leslie	Mar 2020	#8
Thanx for additional info.	sprinkleeninow	Mar 2020	#9
Quinolones are bad news.	roamer65	Mar 2020	#10
Hydroxychloroquine is not a fluoroquinolone	elias7	Mar 2020	#11
I experienced massive side effects from Cipro.	roamer65	Mar 2020	#13
I'm not minimizing what you went through	elias7	Mar 2020	#20
Well I have chloroquine here at home	Drahthaardogs	Mar 2020	#12
This guy talks about how those meds help transfer zinc	Hassin Bin Sober	Mar 2020	#14
Zicam	melm00se	Mar 2020	#15
Yeah, my partner made me a believer. It works.	Hassin Bin Sober	Mar 2020	#17
One thing to bear in mind	melm00se	Mar 2020	#18
Probably just going to take a daily to make sure the zinc is up to par.	Hassin Bin Sober	Mar 2020	#19
Thanks for validating what I got out of it	scipan	Mar 2020	#16

Response to Desert_Leslie (Original post)

Thu Mar 12, 2020, 05:26 PM

ancianita (33,764 posts)

1. Why not?! It looks as if it calls for a cocktail of viral drugs. I'm glad they feel they could help.

Even if this is leverage for later.

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Response to ancianita (Reply #1)

Thu Mar 12, 2020, 05:32 PM

Pachamama (16,778 posts)

3. "Anti viral drugs"

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Response to Desert_Leslie (Original post)

Thu Mar 12, 2020, 05:27 PM

at140 (6,097 posts)

2. Unless those Meds are imported from China

I can't believe we cannot manufacture anti-biotics in US without ingredients imported from China.

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Response to Desert_Leslie (Original post)

Thu Mar 12, 2020, 05:51 PM

dixiegrrrrl (60,007 posts)

4. Every dim watted twit head is gonna panic now, hearing only HIV...

"Oh my god, they are trying to infect us with that damn queer virus!!!!!!!!!!"

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Response to dixiegrrrrl (Reply #4)

Thu Mar 12, 2020, 05:56 PM

flying rabbit (4,513 posts)

7. Yep...

... I can see that.

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Response to Desert_Leslie (Original post)

Thu Mar 12, 2020, 05:51 PM

louis-t (22,762 posts)

5. But trumpie knows more than these guys, so

don't hold your breath.

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Response to Desert_Leslie (Original post)

Thu Mar 12, 2020, 05:53 PM

sprinkleeninow (19,605 posts)

6. Just contacted my PCP doc and gave staff this website link. She says thank you.

Doc most likely knows this, but patient/provider rapport is always welcomed. And interesting.

Thanks for the post. The second time I read regarding this recently. What if????

Oh My Dear God!!

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Response to sprinkleeninow (Reply #6)

Thu Mar 12, 2020, 05:58 PM

Desert_Leslie (131 posts)

8. Me Too

Yep, I figure the doctors are buried right now. I sent it to my PCP also, along with a paper that came out 2 days ago entitled:

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

You can find it by Googling.

In the paper they discuss the use of Hydroxychloroquine (brand name = Plaquenil) at more length.

Also, a really FANTASTIC resource is a YouTube channel entitled MedCram. Run by a multi-boarded MD who is great at explaining the nitty-gritty and keeping everyone up to date. That's where I found this Plaquenil info.

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Response to Desert_Leslie (Reply #8)

Thu Mar 12, 2020, 06:03 PM

sprinkleeninow (19,605 posts)

9. Thanx for additional info.

They are covered up more than ever and it doesn't hurt to offer insight.

Good on you!

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Response to Desert_Leslie (Original post)

Thu Mar 12, 2020, 07:14 PM

roamer65 (36,195 posts)

10. Quinolones are bad news.

I am deathly allergic to them. Anything with “quin” in its name is usually a quinolone.

Ciprofloxacin is also a quinolone, with a black box FDA warning.

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Response to roamer65 (Reply #10)

Thu Mar 12, 2020, 10:12 PM

elias7 (3,775 posts)

11. Hydroxychloroquine is not a fluoroquinolone

Nor is quinidine or quinine...

Most folks tolerate fluoroquinolones just fine. I believe the black box warning is for tendinopathy (like a spontaneous Achilles’ tendon rupture) and for a peripheral neuropathy. Very few people people get these side effects. Like most drugs, people can experience both adverse affects and allergic reactions. They are what they are. They save lives and for some the risks outweigh the benefits.

Maybe bad news for you, but not bad news.

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Response to elias7 (Reply #11)

Fri Mar 13, 2020, 02:53 AM

roamer65 (36,195 posts)

13. I experienced massive side effects from Cipro.

Don’t you ever minimize what I or thousands of others went through with that failed chemotherapy drug, regurgitated as an “antibiotic”.

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Response to roamer65 (Reply #13)

Mon Mar 16, 2020, 06:06 PM

elias7 (3,775 posts)

20. I'm not minimizing what you went through

But you should not demonize something that has literally saved millions of lives. I don’t know that cipro is a chemotherapeutic agent, although I see it talked about in those terms on woo sites.

Oxycodone is great after you’ve had surgery for analgesia, but as an opiate, it is addictive and has killed people.

Penicillin can cause anaphylaxis, Stevens-Johnson syndrome, death... but for most, that is not what happens.

Beta blockers, calcium blockers, really any antihypertensive can kill

All meds may have severe life changing side effects

Medications are a trade off. Modern medicine is a risk benefit proposition and the extensive testing meds go through by the FDA as well as ongoing studies by clinicians make all medicines a work in progress.

You may have had a strong negative effect and I would not minimize that, ever. But to reject something based on a singular experience that few people have is like throwing out the baby with the bathwater

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Response to roamer65 (Reply #10)

Thu Mar 12, 2020, 11:01 PM

Drahthaardogs (6,843 posts)

12. Well I have chloroquine here at home

And plan on taking 500 mg/ day when I get sick. I have asthma so fuck it, may as well try

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Response to Desert_Leslie (Original post)

Fri Mar 13, 2020, 04:21 AM

Hassin Bin Sober (25,865 posts)

14. This guy talks about how those meds help transfer zinc

Sounds like zinc supplements may be a good idea. Not so much as a treatment but to make sure you are not zinc deficient.

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Response to Hassin Bin Sober (Reply #14)

Fri Mar 13, 2020, 11:58 AM

melm00se (4,916 posts)

15. Zicam

contains zinc and is one thing my father, as an MD, swears by.

it doesn't cure diseases but it absolutely shortens up the length of time the symptoms stick around.

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Response to melm00se (Reply #15)

Fri Mar 13, 2020, 02:06 PM

Hassin Bin Sober (25,865 posts)

17. Yeah, my partner made me a believer. It works.

I wonder if it works by bringing zinc deficiency up to par.

According to the video, you need that other medicine to help saturate the cells. Either way, it’s better news.

I’d like to see how his hypothesis, that China has better outcomes due to that regime, plays out.

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Response to Hassin Bin Sober (Reply #17)

Fri Mar 13, 2020, 02:28 PM

melm00se (4,916 posts)

18. One thing to bear in mind

is that zinc, in high doses, is toxic.

Because of this, the idea that if a little bit helps a lot is better needs to be curbed.

Additionally, if you take dietary supplements that contain zinc, you need to be really careful about using other products that contain inc.

Also, zicam, while there is some clinical (and anecdotal) evidence that it works, it has never been evaluated by the FDA

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Response to melm00se (Reply #18)

Fri Mar 13, 2020, 02:45 PM

Hassin Bin Sober (25,865 posts)

19. Probably just going to take a daily to make sure the zinc is up to par.

I used to take a daily. I don’t know why I stopped - just laziness I guess. We have been eating much better the last several years so I haven’t felt like I’m neglecting.

My partner literally forces zicam on me when I start to get sick. For some reason he is under the impression I’m a big baby when I get sick. I just don’t see it. Lol.

We both had influenza type A in February. He works in a hospital so he got tested after taking a day off for not feeling well. It was when stuff was starting to get real around these parts. They sent him home with some tamiflu. I proceeded to get sick that night and had a prescription called in.

Now the dilemma is do I join this new gym that I’ve had my eye on? We just moved near Chinatown in Chicago. I haven’t worked out in a couple months with being busy with the move. So I feel like crap.

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Response to Hassin Bin Sober (Reply #14)

Fri Mar 13, 2020, 12:36 PM

scipan (1,960 posts)

16. Thanks for validating what I got out of it

Checked that my multi does indeed have 100 percent rda so I'm good.

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