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denem

(11,045 posts)
Sat Apr 11, 2020, 10:12 AM Apr 2020

WHO Says Looking Into Reports of Some COVID Patients Testing Positive Again

Source: New York Times

GENEVA — The World Health Organization (WHO) said on Saturday that it was looking into reports of some COVID-19 patients testing positive again after initially testing negative for the disease while being considered for discharge.

South Korean officials on Friday reported 91 patients thought cleared of the new coronavirus had tested positive again. Jeong Eun-kyeong, director of the Korea Centers for Disease Control and Prevention, told a briefing that the virus may have been "reactivated" rather than the patients being re-infected.

The Geneva-based WHO, asked about the report from Seoul, told Reuters in a brief statement: "We are aware of these reports of individuals who have tested negative for COVID-19 using PCR (polymerase chain reaction) testing and then after some days testing positive again.

"We are closely liaising with our clinical experts and working hard to get more information on those individual cases. It is important to make sure that when samples are collected for testing on suspected patients, procedures are followed properly," it said.


Read more: https://www.nytimes.com/reuters/2020/04/11/world/asia/11reuters-health-coronavirus-who.html



There have been a number of anacdoatal reports of people testing positive after earlier testing negative. This is hard evidence. The Korean CDC is suggesting "reactivation". There is also evidence for reinfection.

A team ... based at Fudan University in Shanghai, screened the blood of 175 Chinese patients who had recovered from mild forms of the illness to look for neutralizing antibodies.

Nearly a third of 175 patients studied produced low antibody levels. In 10 people, antibody levels were so low they could not be detected.

https://www.smh.com.au/national/scientists-at-odds-after-study-finds-coronavirus-antibody-anomaly-20200410-p54iwm.html
24 replies = new reply since forum marked as read
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WHO Says Looking Into Reports of Some COVID Patients Testing Positive Again (Original Post) denem Apr 2020 OP
Not surprising to me bucolic_frolic Apr 2020 #1
i think the long term impacts will be a bear. mopinko Apr 2020 #5
worst thing is having a problem doctors dont believe in bucolic_frolic Apr 2020 #7
What did you have imavoter Apr 2020 #11
incompetent doctors /nt bucolic_frolic Apr 2020 #12
I gathered that. imavoter Apr 2020 #13
Seriously bucolic_frolic Apr 2020 #14
having a problem doctors dont believe in lagomorph777 Apr 2020 #22
my fibromyalgia blew up w wnv. mopinko Apr 2020 #23
Yup - the germ theory of disease seems to be "just a theory" to many docs still. lagomorph777 Apr 2020 #24
Agreed DENVERPOPS Apr 2020 #10
Lyme and Epstein-Barr Virus (and a number of other chronic infections). lagomorph777 Apr 2020 #20
Happy to see you posted this! bluestarone Apr 2020 #2
This is the scariest thing of all. earthside Apr 2020 #3
That's what I keep wondering. ucrdem Apr 2020 #19
So far, the only way out of lockdown is mass testing. lagomorph777 Apr 2020 #21
Good to hear they cited the need to evaluate testing procedures. Raven123 Apr 2020 #4
They already know that most of the tests Igel Apr 2020 #8
People who were symptomatic and have tested positive denem Apr 2020 #9
Ayup greenjar_01 Apr 2020 #17
So much for the idea that we can test for C-19 antibodies and then let those people go back to work Botany Apr 2020 #6
not good not good at all. riversedge Apr 2020 #15
Keep looking WHO, and let us know when you have an answer. Steelrolled Apr 2020 #16
That's bad news . I mean good research and more analysis of data but low antibody lunasun Apr 2020 #18

bucolic_frolic

(43,161 posts)
1. Not surprising to me
Sat Apr 11, 2020, 10:32 AM
Apr 2020

Lyme disease, for example, is notorious for delays in detection, false readings, and going underground or hiding in tissue. We want this disease to be once and done, like a vaccination. But could it be more permanent to the human species? I'm no expert on how it stacks up as a virus. HPV, many types of virus that cause various warts, stay with us.

mopinko

(70,103 posts)
5. i think the long term impacts will be a bear.
Sat Apr 11, 2020, 10:58 AM
Apr 2020

i had a moderate case of wnv, and it took me 10 years to shake it off.
sneaky as this thing seems to be, i fear survivors are gonna have a rough time.
i just hope they catch on fast to long term impacts, which i have seen them doing.
the worst thing is having a problem doctors dont believe in.

bucolic_frolic

(43,161 posts)
7. worst thing is having a problem doctors dont believe in
Sat Apr 11, 2020, 11:29 AM
Apr 2020

Oh yes! Which shoots the myth that they can look at you for ten minutes and have a great idea of what's going on, just add a lab test. Why do they ask so many questions? To help them narrow it down because they only have a general idea. And if that idea is off, you are in no man's land.

Once I blew through half a dozen doctors all of whom said the same thing and gave antibiotics, went downhill further every time. None of them had a clue. Even the deep alt doc who finally got a diagnosis was getting his advice from emails to doctors in Germany. He shared one or two with me. So I am skeptical, and avoid them like the plague.

lagomorph777

(30,613 posts)
22. having a problem doctors dont believe in
Mon Apr 13, 2020, 10:26 AM
Apr 2020

Lyme and Epstein-Barr patients have dealt with this for decades. These things are destroying millions of lives.

DENVERPOPS

(8,820 posts)
10. Agreed
Sat Apr 11, 2020, 11:54 AM
Apr 2020

Look at Herpes Zoster.....(Shingles) It hangs out in your spine and can come out time and time again if you aren't vaccinated...

lagomorph777

(30,613 posts)
20. Lyme and Epstein-Barr Virus (and a number of other chronic infections).
Mon Apr 13, 2020, 10:23 AM
Apr 2020

It would be very shitty news if we find out that COVFEFE-19 can go chronic.

bluestarone

(16,940 posts)
2. Happy to see you posted this!
Sat Apr 11, 2020, 10:34 AM
Apr 2020

We just DO NOT have a grip on this yet! Lots of investigating to be done BEFORE we are sure!

earthside

(6,960 posts)
3. This is the scariest thing of all.
Sat Apr 11, 2020, 10:39 AM
Apr 2020

No or low levels of immunity will mean a reorganization of society.

We shouldn't be talking about "re-opening" the economy, but rather discussing and planning for how we are going to live with this virus. We can't let ourselves slip into an economic depression or a cultural dark age, that means adapting to prevention of COVID-19.

ucrdem

(15,512 posts)
19. That's what I keep wondering.
Mon Apr 13, 2020, 04:21 AM
Apr 2020

What is the end game on this lockdown? Unless we're waiting for a vaccination, which could be a long wait, how is a month from now going to be any different from now?

lagomorph777

(30,613 posts)
21. So far, the only way out of lockdown is mass testing.
Mon Apr 13, 2020, 10:24 AM
Apr 2020

No tech breakthrough is needed, but we will have to find a way to bypass Trump's blockade of testing.

However, re-activations or re-infections will complicate that path considerably.

Raven123

(4,842 posts)
4. Good to hear they cited the need to evaluate testing procedures.
Sat Apr 11, 2020, 10:44 AM
Apr 2020

Also need to periodically run quality assurance tests on the the test kits.

Igel

(35,309 posts)
8. They already know that most of the tests
Sat Apr 11, 2020, 11:33 AM
Apr 2020

have a high rate of false negatives.

It's also easy to get bad samples.

The fact that it's looking for RNA and not "live" viruses is also a problem. Dead virions, live virions, both test positive.

You don't know what the tests are like, how they work, you don't understand the data--and that's easy. Don't understand the data, then it's easy to misinterpret the data. Remember: Data are mute, they say nothing. When somebody says, "Just let the data speak for themselves" there should be utter silence until the speaker says, "Now I'll tell you what I think the correct interpretation is and why." If the speaker says anything else, he's trying to deceive you into thinking that somehow it's an a priori truth and not an interpretation--mostly to avoid that nasty bit where he has to explain, logically, how he reached his conclusions.

 

denem

(11,045 posts)
9. People who were symptomatic and have tested positive
Sat Apr 11, 2020, 11:43 AM
Apr 2020

then later have no measurable antibodies, is not a case of false negatives. That is a foundation for reinfection hypothesis.

Botany

(70,504 posts)
6. So much for the idea that we can test for C-19 antibodies and then let those people go back to work
Sat Apr 11, 2020, 11:15 AM
Apr 2020

.... having the disease can give you immunity and or limited immunity. But I am not a Dr, a micro-
biologist, or an epidemiologist so I'll just wait until what experts like Laura Ingraham has to say on
the subject.

 

Steelrolled

(2,022 posts)
16. Keep looking WHO, and let us know when you have an answer.
Sat Apr 11, 2020, 05:24 PM
Apr 2020

I'm a bit skeptical of analysis from armchair experts on the Internet.

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