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muriel_volestrangler

(101,265 posts)
Mon Nov 23, 2020, 04:24 AM Nov 2020

Oxford AstraZeneca Covid vaccine has 70% efficacy, data reveals

Source: The Guardian

A coronavirus vaccine developed in the UK can prevent 70.4% of people from getting Covid-19 and up to 90% if a lower dose is used, according to data.

Oxford University and AstraZeneca have announced their jab is effective in preventing many people getting ill and it has been shown to work in different age groups, including the elderly. There are early indications it might also help stop the spread of the disease.
...
Oxford University said interim analysis from its phase 3 vaccine trial showed that the efficacy of their vaccine is 70%. But that came from combining the results of two different dosing regimes, one of which was 90% and the other was 62%. The 90% regime involved a half-dose first and then a full dose of the vaccine later. The interim analysis was based on 131 infections among participants who received the vaccine and those in a control group who were given an established meningitis shot.

In a statement, Prof Andrew Pollard, the director of the Oxford Vaccine Group and chief investigator of the Oxford vaccine trial, said: “These findings show that we have an effective vaccine that will save many lives. Excitingly, we’ve found that one of our dosing regimens may be around 90% effective and if this dosing regime is used, more people could be vaccinated with planned vaccine supply.

Read more: https://www.theguardian.com/society/2020/nov/23/astrazeneca-says-its-coronavirus-vaccine-has-70-per-cent-efficacy-covid-oxford-university

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durablend

(7,455 posts)
7. But the question is
Mon Nov 23, 2020, 09:09 AM
Nov 2020

Will you be able to find out what drug the individual provider is shooting people up with?

IsItJustMe

(7,012 posts)
13. Some vaccines will become available in your area while others will not, at least for a time.
Mon Nov 23, 2020, 04:56 PM
Nov 2020

I talked with the local Health Department in my area and they tell me that they are expecting a limited number of a vaccines to become available, possibly, toward mid to late December. They do not know which one it will be. They do not know how many vaccines will be available. They do not know exactly when these vaccines will be available.

From what I gathered, unless you are willing to wait for when and if another vaccine becomes available, there is not going to be a lot of choice in the matter.

You may be able to travel outside your area or travel to another state to get a different vaccine. Not sure.

MySideOfTown

(225 posts)
6. They have receipts and links
Mon Nov 23, 2020, 08:10 AM
Nov 2020

for every case they cite. I didn't go thru all of them. You can also easily search any corporation in any business. It's a deep data base.

truthisfreedom

(23,139 posts)
9. Such a strange analysis to use both numbers at once and arrive at the low 70% rather than 90%
Mon Nov 23, 2020, 12:10 PM
Nov 2020

So weird. Every other article I've read has mentioned the 90% figure in the headline.

roamer65

(36,744 posts)
10. So it's a two dose like Pfizer and Moderna to get to 90 pct.
Mon Nov 23, 2020, 12:16 PM
Nov 2020

No big deal.

Two dose is safer. It should avoid a cytokine storm in patients.

muriel_volestrangler

(101,265 posts)
11. It's always a 2 dose jab; the higher efficiacy is with a half-dose for the first
Mon Nov 23, 2020, 01:01 PM
Nov 2020

and then a full one, rather than 2 full ones. Which has them a little puzzled; the idea of the half-dose was to see if they could 'get away' with it, not because they thought it would be better.

roamer65

(36,744 posts)
12. A lower first dose has less adverse reactions.
Mon Nov 23, 2020, 01:36 PM
Nov 2020

First safely stimulate antibody production, then boost it with another dose of antigen.

If I remember right Hepatitis B is a two dose regimen as well. May have have changed since I received it.

LeftishBrit

(41,203 posts)
15. It seems to depend on the dosing procedure
Mon Nov 23, 2020, 09:57 PM
Nov 2020

Interestingly, 'less seems to be more' here. A half dose followed by a full dose seems to be about 90% effective, while two doses are only about 60% effective.

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