J&J Covid Vaccine Reviewed by EU Regulator After Blood Clots

[brooklynite]

Source: Bloomberg

The European Union’s drug regulator has started a review to assess blood clots in people who received Johnson & Johnson’s Covid-19 vaccine.

Four serious cases of unusual clots accompanied by low blood platelets, one of which was fatal, have emerged after immunization with the J&J shot, the European Medicines Agency said Friday. The regulator is now scrutinizing potential safety issues for two Covid vaccines, after AstraZeneca Plc’s shot was possibly linked to a rare blood-clotting disorder.

J&J is working with regulators to assess data on the rare clots, and “at present, no clear causal relationship has been established” with the vaccine, the company said in an e-mailed statement. The shares traded as much as 1.6% lower.

One of the cases following J&J vaccinations happened during a clinical trial. At the time, the company said it had found no evidence the vaccine was at fault. Three others occurred in the U.S., where the shot has been given to almost 5 million people.

Read more: https://www.bloomberg.com/news/articles/2021-04-09/eu-regulator-investigating-blood-clots-after-j-j-covid-vaccine

[NH Ethylene]

1. Johnson & Johnson is also an adenovirus vaccine like Astro Zenica.

So it's not surprising they have the same possible rare side effect.

As long as it's this uncommon, its benefit outweighs its risks.

[agtcovert]

2. I'm a sample size of one...

Had it last Thursday. Felt like crud Friday, arm hurt some.

Fine now. Glad I got it.

[Deminpenn]

3. Isn't the standard that the side effect

has to occur more often in those getting the J&J vaccine than it would statistically be expected to occur under normal circumstances?

3 in 5 million is an extremely low occurrance.

Info on DVT/thrombosis from the CDC: https://www.cdc.gov/ncbddd/dvt/data.html

and https://www.cdc.gov/ncbddd/dvt/infographic-impact.html

5-8% of Americans have a genetic predisposition to clots and about 900,000 die from clots annually.

[Ace Rothstein]

4. I believe it is 6 in 7 million but it is not a common type of clotting.

It is also only happening in younger women, 18-48, only so far so not sure why they are completely pausing the rollout.

[Deminpenn]

5. Just using the numbers from the OP link

CDC has more statistical info on blood clots