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Omaha Steve

(99,653 posts)
Mon Jan 10, 2022, 07:07 PM Jan 2022

In 1st, US surgeons transplant pig heart into human patient

Source: AP

By CARLA K. JOHNSON

In a medical first, doctors transplanted a pig heart into a patient in a last-ditch effort to save his life and a Maryland hospital said Monday that he’s doing well three days after the highly experimental surgery.

While it’s too soon to know if the operation really will work, it marks a step in the decades-long quest to one day use animal organs for life-saving transplants. Doctors at the University of Maryland Medical Center say the transplant showed that a heart from a genetically modified animal can function in the human body without immediate rejection.

The patient, David Bennett, a 57-year-old Maryland handyman, knew there was no guarantee the experiment would work but he was dying, ineligible for a human heart transplant and had no other option, his son told The Associated Press.

“It was either die or do this transplant. I want to live. I know it’s a shot in the dark, but it’s my last choice,” Bennett said a day before the surgery, according to a statement provided by the University of Maryland School of Medicine.

https://storage.googleapis.com/afs-prod/media/eaca8f3e012b4e1bb4d225bf728cfb2d/1

In this photo provided by the University of Maryland School of Medicine, members of the surgical team show the pig heart for transplant into patient David Bennett in Baltimore on Friday, Jan. 7, 2022. On Monday, Jan. 10, 2022 the hospital said that he's doing well three days after the highly experimental surgery. (Mark Teske/University of Maryland School of Medicine via AP)
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Read more: https://apnews.com/article/pig-heart-transplant-6651614cb9d73bada8eea2ecb6449aef

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In 1st, US surgeons transplant pig heart into human patient (Original Post) Omaha Steve Jan 2022 OP
Pigs are used for heart valves and skin for burns, a lady I knew had a pigs bladder due to bladder c flying_wahini Jan 2022 #1
On the other hand, pigs think we suck. ret5hd Jan 2022 #2
I trust the pigs. nt reACTIONary Jan 2022 #11
I heard a NPR blerb about a special pig kidney being used on a human mitch96 Jan 2022 #3
Wow. Snackshack Jan 2022 #4
+ agree. n/t iluvtennis Jan 2022 #8
every day is a blessing, n/t mike_c Jan 2022 #5
Curious as to why Jilly_in_VA Jan 2022 #6
Good question. I looked into it... reACTIONary Jan 2022 #12
Figures. Dick Cheney got his new heart when he was 71 n/t TexasBushwhacker Jan 2022 #23
He never had one before Jilly_in_VA Jan 2022 #26
The Washington Post just has this: muriel_volestrangler Jan 2022 #25
Like Dr. Christiaan Barnard and Louis Washkansky Marthe48 Jan 2022 #7
OMG!! Is Josh Hawley still alive??!? lastlib Jan 2022 #9
I don't think he has a heart to give.... reACTIONary Jan 2022 #13
his is a jackass !! monkeyman1 Jan 2022 #18
the jokes write themselves. nt Grasswire2 Jan 2022 #10
That'll do, Pig... Talitha Jan 2022 #14
If the pig was Trump, I think I'd skip the transplant. n/t OnlinePoker Jan 2022 #15
If the pig was TFG, it would have been blocked from donating. Probatim Jan 2022 #22
Donald Trump donated his heart? Oh, wait I misread the the article my bad. cstanleytech Jan 2022 #16
A friend's father was in the NIH trials for the pig heart valve years ago (funny story) Bluejeans Jan 2022 #17
That's nothing. I'd like to meet the surgeon Jerry2144 Jan 2022 #19
Dick Cheney is following this story closely FakeNoose Jan 2022 #20
This post immediately follows one about Mccarthy RainCaster Jan 2022 #21
The queen doesn't like this. Kablooie Jan 2022 #24
Avenue for zoonotic transfer of viruses. roamer65 Jan 2022 #27

flying_wahini

(6,600 posts)
1. Pigs are used for heart valves and skin for burns, a lady I knew had a pigs bladder due to bladder c
Mon Jan 10, 2022, 07:10 PM
Jan 2022

And that was in 1975.

Pigs are pretty amazing.

mitch96

(13,907 posts)
3. I heard a NPR blerb about a special pig kidney being used on a human
Mon Jan 10, 2022, 07:20 PM
Jan 2022

The patient was brain dead but otherwise a viable recipient. The family agreed to the procedure. Apparently pig kidneys have an enzyme that the human body rejects. This pig was bred to not have this enzyme present. The minute the kidney was attached to the recipient it produced urine and was not rejected. The article mentioned that this would be a viable alternative for a patient waiting for a donor kidney.. Kinda neat...
m

Jilly_in_VA

(9,979 posts)
6. Curious as to why
Mon Jan 10, 2022, 07:25 PM
Jan 2022

he was ineligible for a human heart transplant. Too sick? Sometimes they transplant human hearts into sicker patients that would not be transplanted into healthier patients. From older donors, for instance. Transplant rules are kind of weird.

reACTIONary

(5,770 posts)
12. Good question. I looked into it...
Mon Jan 10, 2022, 07:54 PM
Jan 2022

....and found this:

https://www.hopkinsmedicine.org/transplant/referring-physicians/heart-transplant-criteria.html

Following are the absolute ineligibilities. Just being a smoker and you are out.

Absolute Contraindications
Absolute contraindications for adults and children include, but may not be limited to:

Major systemic disease
Age inappropriateness (70 years of age)
Cancer in the last 5 years except localized skin (not melanoma) or stage I breast or prostate
Active smoker (less than 6 months since quitting)
Active substance abuse
HIV
Severe local or systemic infection
Severe neurologic deficits
Major psychiatric illness or active substance abuse that cannot be managed sufficiently to allow post-transplant care and safety

muriel_volestrangler

(101,320 posts)
25. The Washington Post just has this:
Tue Jan 11, 2022, 04:53 AM
Jan 2022
Doctors at the hospital and elsewhere had deemed Bennett ineligible for a human heart transplant after reviewing his medical records, leaving the experimental surgery as his “only option for survival,” the statement said. It did not specify what disqualified him.

https://www.washingtonpost.com/science/2022/01/11/pig-heart-transplant-genetically-modified/

and I guess confidentiality rules may prevent them from saying more.

Marthe48

(16,963 posts)
7. Like Dr. Christiaan Barnard and Louis Washkansky
Mon Jan 10, 2022, 07:27 PM
Jan 2022

This historic transplant will forever be a milestone.

Thanks to the scientists, medical professionals, the courageous patient, and the pig for this scintillating moment in human endeavor.

Bluejeans

(68 posts)
17. A friend's father was in the NIH trials for the pig heart valve years ago (funny story)
Mon Jan 10, 2022, 09:26 PM
Jan 2022

When I was in high school, the father of one of my friends was in the NIH trials for transplanting pig heart valves into humans. Eric's dad was in really bad shape from the heart valve problem, so he felt he had nothing to lose by going through the trial surgery.

Months later after his recovery from the successful surgery, Eric's dad kidded my father and me, "It's a good thing I'm Catholic; I could never be kosher with that pig valve in me!"

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