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BumRushDaShow

(128,846 posts)
Fri Mar 24, 2023, 10:42 AM Mar 2023

Pfizer's Covid drug Paxlovid may reduce the risk of developing long Covid, study says

Source: CNBC

People who take Pfizer ’s Covid antiviral treatment Paxlovid shortly after infection may reduce their risk of developing long Covid, regardless of their age, vaccination status or infection history, new research suggests.

The study, published in the journal JAMA Internal Medicine on Thursday, found that people who took Paxlovid within five days of a positive Covid test saw a 26% lower risk of long Covid compared with those who didn’t receive it. More than 35,000 people took the oral Covid pill in the study, while 246,000 did not.

The study only enrolled people who are eligible for Paxlovid under emergency use authorization. That includes adults over 50, or those who have an underlying medical condition such as high blood pressure or diabetes. The findings suggest the benefits of Paxlovid may go beyond what the drug is designed for, which is to treat adults and children who are at a higher risk of ending up in the hospital or dying from a Covid infection.

The drug still demonstrated that intended benefit in the study, lowering the risk of death by 47% and hospitalization by 24% about a month after initial infection. The new study comes as researchers work to fill the knowledge gap about long Covid, an often debilitating condition with limited data and no proven treatment available.

Read more: https://www.cnbc.com/2023/03/24/pfizer-covid-drug-paxlovid-may-reduce-the-risk-of-long-covid-study.html



Link to JAMA study publication - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2802878
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Pfizer's Covid drug Paxlovid may reduce the risk of developing long Covid, study says (Original Post) BumRushDaShow Mar 2023 OP
I've taken Paxlovid Darwins_Retriever Mar 2023 #1
Yep, my experience as well. Within 6 hours I was noticeably better. lostnfound Mar 2023 #7
on fourth dose right now- ugh PuraVidaDreamin Mar 2023 #2
Yur body temperature is highest in late afternoon, early evening Warpy Mar 2023 #3
That's good to know. hamsterjill Mar 2023 #4
They promote this as if it's something new. live love laugh Mar 2023 #5
Well they submitted their application for full approval BumRushDaShow Mar 2023 #6

Darwins_Retriever

(853 posts)
1. I've taken Paxlovid
Fri Mar 24, 2023, 11:17 AM
Mar 2023

It worked amazingly well. 3 horse pills a day kinda sucked, but can't argue with the results. 67 years old, vaccinated (1 booster).

PuraVidaDreamin

(4,099 posts)
2. on fourth dose right now- ugh
Fri Mar 24, 2023, 11:40 AM
Mar 2023

my luck ran out. made it 3 years. not sure why my shift button isn't working sorry no capitals. temped as high as 105 Wed night. last night after 3rd dose
significant gi distress- several trips to the lieu. metal taste in
the mouth. this morning temp just below 100. really thought long and
hard about taking this 4th dose. just gotta keep hydrating.

Warpy

(111,245 posts)
3. Yur body temperature is highest in late afternoon, early evening
Fri Mar 24, 2023, 01:12 PM
Mar 2023

so you'll probably spike a temp again. 105 impressive, your doc needs to know about that, especially if it didn't come down with an anti fever medication.

Honestly, there are some times I think the cure really is worse than the disease. However, if this stuff really does prevent long Covid, it's probably worth it.

hamsterjill

(15,220 posts)
4. That's good to know.
Fri Mar 24, 2023, 04:24 PM
Mar 2023

I took Paxlovid and had almost immediate improvement in how I felt. I did rebound, however, but it wasn’t horrible.

Here’s hoping this information leads to even better treatment. Everything they can learn about viruses benefits down the line in treatment and understanding.

live love laugh

(13,100 posts)
5. They promote this as if it's something new.
Fri Mar 24, 2023, 07:47 PM
Mar 2023

That’s always been the reason for taking it.

Guess the ad campaign: “If it’s Covid then Paxlovid” isn’t lucrative enough.

BumRushDaShow

(128,846 posts)
6. Well they submitted their application for full approval
Fri Mar 24, 2023, 07:58 PM
Mar 2023

(i.e. to no longer have to be under an Emergency Use Authorization (EUA)) and were recommended for it by the FDA advisory panel last week, so once the final signoff happens - $$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$

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