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appalachiablue

(41,127 posts)
Tue Nov 17, 2020, 05:00 PM Nov 2020

Immunity to the Coronavirus May Last Years, New Data Hint: NYT

The New York Times, 'Immunity to the Coronavirus May Last Years, New Data Hint,' Nov. 17, 2020.

How long might immunity to the coronavirus last? Years, maybe even decades, according to a new study — the most hopeful answer yet to a question that has shadowed plans for widespread vaccination. Eight months after infection, most people who have recovered still have enough immune cells to fend off the virus and prevent illness, the new data show. A slow rate of decline in the short term suggests, happily, that these cells may persist in the body for a very, very long time to come.

The research, published online, has not been peer-reviewed nor published in a scientific journal. But it is the most comprehensive and long-ranging study of immune memory to the coronavirus to date. “That amount of memory would likely prevent the vast majority of people from getting hospitalized disease, severe disease, for many years,” said Shane Crotty, a virologist at the La Jolla Institute of Immunology who co-led the new study. The findings are likely to come as a relief to experts worried that immunity to the virus might be short-lived, and that vaccines might have to be administered repeatedly to keep the pandemic under control.

And the research squares with another recent finding: that survivors of SARS, caused by another coronavirus, still carry certain important immune cells 17 years after recovering. The findings are consistent with encouraging evidence emerging from other labs. Researchers at the University of Washington, led by the immunologist Marion Pepper, had earlier shown that certain “memory” cells that were produced following infection with the coronavirus persist for at least three months in the body. A study published last week also found that people who have recovered from Covid-19 have powerful and protective killer immune cells even when antibodies are not detectable.

These studies “are all by and large painting the same picture, which is that once you get past those first few critical weeks, the rest of the response looks pretty conventional,” said Deepta Bhattacharya, an immunologist at the University of Arizona.

Akiko Iwasaki, an immunologist at Yale University, said she was not surprised that the body mounts a long-lasting response because “that’s what is supposed to happen.” Still, she was heartened by the research: “This is exciting news.” A small number of infected people in the new study did not have long-lasting immunity after recovery, perhaps because of differences in the amounts of coronavirus they were exposed to. But vaccines can overcome that individual variability, said Jennifer Gommerman, an immunologist at the University of Toronto.

..In recent months, reports of waning antibody levels have created worry that immunity to the coronavirus may disappear in a few months, leaving people vulnerable to the virus again. But many immunologists have noted that it is natural for antibody levels to drop. Besides, antibodies are just one arm of the immune system...

https://www.msn.com/en-us/health/medical/immunity-to-the-coronavirus-may-last-years-new-data-hint/ar-BB1b6dwt?ocid=msedgntp

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Immunity to the Coronavirus May Last Years, New Data Hint: NYT (Original Post) appalachiablue Nov 2020 OP
Call me skeptical. Laelth Nov 2020 #1
Meaningless until it is peer-reviewed and published in the Journal of the AMA, the British Medical Aristus Nov 2020 #2
Forbes: appalachiablue Nov 2020 #3

Laelth

(32,017 posts)
1. Call me skeptical.
Tue Nov 17, 2020, 06:49 PM
Nov 2020

And can somebody explain the “long-termer” phenomenon to me? It’s real.

Truth is that we still know very little. That said, we know a lot more about COVID-19 now than we did early this year.

-Laelth

Aristus

(66,316 posts)
2. Meaningless until it is peer-reviewed and published in the Journal of the AMA, the British Medical
Tue Nov 17, 2020, 07:52 PM
Nov 2020

Journal, the Journal of the AAPA, or the New England Journal of Medicine.

appalachiablue

(41,127 posts)
3. Forbes:
Tue Nov 17, 2020, 08:55 PM
Nov 2020

..TOPLINE Immunity to the novel coronavirus may last eight months or longer, according to a new study authored by respected scientists at leading labs, which found that individuals who recovered from the coronavirus developed “robust” levels of B cells and T cells (necessary for fighting off the virus) and “these cells may persist in the body for a very, very long time.”

KEY FACTS Researchers collected blood samples from 185 patients between the ages of 19 to 81 who had tested positive for the coronavirus (SARS-CoV-2) early in the pandemic and discovered that most had enough immune cells to combat the virus and prevent reinfection. In addition, these antibodies were “durable,” showing remarkably slow rates of decline that were consistent with many years, and potentially even decades, of protection...
https://www.forbes.com/sites/tommybeer/2020/11/17/coronavirus-immunity-may-last-years-possibly-even-decades-study-suggests

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