Another Booster? A Vaccine for Omicron? Here's What Could Be Next For COVID Vaccines: NPR
- NPR, April 4, 2022.
Most vaccinated people will probably require yet another COVID-19 vaccine booster shot in the fall, a top Food and Drug Administration official said Monday. "That's when we'll probably have a fair amount of waning immunity in combination with likely further evolution of the virus, along with people going back inside," where the coronavirus spreads more easily, Dr. Peter Marks, director of the FDA's Center for Biologics Evaluation and Research, told NPR in an interview.
Marks says the U.S. must start planning now for whether everyone needs another shot and, if so, what kind of shot exactly. "We could basically wait until another wave comes along and then try to make another vaccine and try to deal with it, but I think we know that doesn't work, because we can't manufacture and deploy vaccine fast enough," Marks says.
The FDA is convening a special meeting of the agency's independent outside advisers on Wednesday for a daylong meeting to begin to plan the next round of boosters. The meeting comes about a week after the agency authorized a fourth shot a second booster for anyone age 50 or older to shore up immunity ahead of a possible new surge sooner than the fall. A more contagious omicron subvariant known as BA.2, which has fueled surges in other countries, is now dominant in the U.S., raising fears of another surge.
The tricky part of determining what do in the fall is determining what version of the coronavirus will be dominant by then, Marks says. It could be the omicron variant, but it could also be an entirely new variant. That raises doubts about just giving people a fifth shot of the current vaccine, he says...
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https://www.npr.org/sections/health-shots/2022/04/04/1090912213/another-booster-a-vaccine-for-omicron-heres-what-could-be-next-for-covid-vaccine
PSPS
(13,614 posts)appalachiablue
(41,174 posts)and there are some updates come before long.
captain queeg
(10,247 posts)I was scheduled for today but they called me on Sunday to say they were only giving Moderna shots today. Id signed up for Pfizer. But now I kind of wish Id just taken the Moderna shot. From what Ive read combing different brands may give better protection.
StevieM
(10,500 posts)I definitely want Moderna again for my fourth.
lagomorph777
(30,613 posts)I've had three Pfizers; the third went pretty badly. Is your choice based on side effects, or the wish to mix/match for better mix of antibodies, or...?
Thanks!
StevieM
(10,500 posts)I heard that there are benefits to mixing and matching. It felt like it made sense to follow up my initial Pfizer vaccination with Moderna for my boosters. That way each vaccine could benefit me in its own way.
It would have been interesting if Novavax had been available. That would really have been an opportunity to get two different vaccines that worked on totally different principles.
lagomorph777
(30,613 posts)Mix & match would surely stimulate multiple groupings of antibodies.
Is J&J still around? That's a more traditional killed-virus I think.
StevieM
(10,500 posts)It didn't seem to have the same efficacy rate as the other vaccines. When I was first preparing to be vaccinated, I said that I didn't care whether I got Pfizer or Moderna, I just wanted one or the other, and not J&J.
Novavax appears to have gotten better results, but the FDA is slow walking its approval. It is available in other countries throughout Europe and Asia. It is likely to be approved here within a month or two, possibly sooner. Novavax is also more traditional vaccine, based on protein sub-units.
J&J is a viral vector vaccine. It contains a piece of a modified virus that is not the virus that causes COVID-19. The vector virus cannot reproduce itself, so it is harmless. This vector virus gives instructions to cells in the body to create an immune response.