Israeli breakthrough helped cure Jimmy Carter’s cancer

[grossproffit]

[quote] An Israeli-tested drug that tackles cancer through sophisticated manipulations of the body’s natural immune system was key in helping rid former US president Jimmy Carter of life-threatening tumors that developed after he was diagnosed with melanoma earlier this year.

Researched in Israel by Professor Jacob Schachter of the Ella Institute for melanoma treatment and research at the Sheba Medical Center in Tel Hashomer, Keytruda is part of a promising new class of drugs called immunotherapies, which harness the body’s immune system to help fight cancer.


The US-based Merck pharmaceutical company’s injectable biotech drug works by blocking a protein found in certain tumors called PD-1, which inhibits the body’s natural response to cancer cells.

Carter, 91, announced Sunday that doctors found no evidence of the four lesions discovered on his brain this summer and no signs of new cancer growth. He revealed in August that he had been diagnosed with melanoma and had begun treatment, including surgery to remove part of his liver, targeted radiation therapy and doses of a recently approved drug to help his immune system seek out any new cancer cells.[/quote]

[url]http://www.timesofisrael.com/israeli-breakthrough-drug-helped-cure-jimmy-carters-cancer/[/url]

BDS!

[Agnosticsherbet]

1. Carter is our greatest elder statesman and a natioanl treasure.

I am glad he will be with us for a while longer.

[catnhatnh]

2. I am so grateful Mr Carter achieved remission...

there is almost no one I would more like to see that happen to.

Except that my younger brother died at 58 this August of the same types of cancer. He died in a hospice because "no existing treatment" offered any hope. Those medical folks did just what they would do for any medicare patient and I applaud their efforts. But what a shame that "all lives" don't equally matter.

[grossproffit]

3. I'm so very sorry for the loss of your brother.

[catnhatnh]

6. TY

I love Carter but it is bittersweet...

Happy Holidays to you and yours!

[R. Daneel Olivaw]

4. Perhaps an Israeli breakthrough will cure itself

of apartheid and land theft...

[azurnoir]

5. Wonderful news about President Carter now about Keytruda

while some research might have done in Israel to call it an Israeli breakthrough drug is a bit of a stretch

Pembrolizumab (formerly MK-3475 and lambrolizumab, trade name Keytruda is a humanized antibody used in cancer immunotherapy. It targets the programmed cell death 1 (PD-1) receptor The drug was initially used in treating metastatic melanoma.

Pembrolizumab was invented by Gregory Carven, Hans van Eenennaam and John Dulos at Organon Biosciences which later became Schering Plough Research Institute and then Merck & Co.[5] MRC Technology humanized the antibody pembrolizumab for Organon in 2006.

On September 4, 2014 the US Food and Drug Administration (FDA) approved pembrolizumab under the FDA Fast Track Development Program. It is approved for use following treatment with ipilimumab, or after treatment with ipilimumab and a BRAF inhibitor in advanced melanoma patients who carry a BRAF mutation.[6] It is marketed by Merck.

https://en.wikipedia.org/wiki/Pembrolizumab

Now about Organon Biosciences

Organon was a pharmaceutical company headquartered in Oss, Netherlands. In November 2007, Schering-Plough Corporation, based in New Jersey, USA, acquired Organon, active pharmaceutical ingredient producer Diosynth (separate from Organon until 2004),[1] and its veterinary pharmaceutical sister company Intervet from Akzo Nobel.[2] In November 2009, Schering-Plough merged with Merck & Co. under the name Merck & Co., known as Merck Sharp & Dohme or MSD outside the United States and Canada.

https://en.wikipedia.org/wiki/Organon_International

[King_David]

7. Ha Ha ....pathetic

This attempt ....


Do you dispute all the Jewish Nobel prizes too ? Despite our tiny number in the world.....

LOL

[azurnoir]

8. No attempt the facts speak for themselves and no I don't dispute Noble prizes

but Keytruda was not invented in Israel or by Israeli's, some sort of reserch or even clinical trials may well have been done in Israel but Keytruda is not an Israeli drug

[King_David]

9. All the Jewish Nobel winners are fake too I hear?

None of them have a Jewish blood line? Right ?



http://www.democraticunderground.com/1134121511


Pathetic ....I have to pinch myself to make sure I am not on some extremist right wing web site.....

[azurnoir]

10. it seems you might be stalking me I pointed out the facts about Keytruda which apparently upset you

you then "puke" up another thread on a different subject and make comments about who has Jewish blood

Pembrolizumab (formerly MK-3475 and lambrolizumab, trade name Keytruda is a humanized antibody used in cancer immunotherapy. It targets the programmed cell death 1 (PD-1) receptor The drug was initially used in treating metastatic melanoma.

Pembrolizumab was invented by Gregory Carven, Hans van Eenennaam and John Dulos at Organon Biosciences which later became Schering Plough Research Institute and then Merck & Co. MRC Technology humanized the antibody pembrolizumab for Organon in 2006.

On September 4, 2014 the US Food and Drug Administration (FDA) approved pembrolizumab under the FDA Fast Track Development Program. It is approved for use following treatment with ipilimumab, or after treatment with ipilimumab and a BRAF inhibitor in advanced melanoma patients who carry a BRAF mutation. It is marketed by Merck.

https://en.wikipedia.org/wiki/Pembrolizumab

Now about Organon Biosciences

Organon was a pharmaceutical company headquartered in Oss, Netherlands. In November 2007, Schering-Plough Corporation, based in New Jersey, USA, acquired Organon, active pharmaceutical ingredient producer Diosynth (separate from Organon until 2004), and its veterinary pharmaceutical sister company Intervet from Akzo Nobel. In November 2009, Schering-Plough merged with Merck & Co. under the name Merck & Co., known as Merck Sharp & Dohme or MSD outside the United States and Canada.

https://en.wikipedia.org/wiki/Organon_International

[King_David]

13. Stalking?

Does that translate as ' wow i am losing another argument here,let me call it stalking'

Bye

[azurnoir]

18. I'm not losing anything the facts surrounding keytruda speak for themselves

here ya go again how many times do you wish me to post this?

Pembrolizumab (formerly MK-3475 and lambrolizumab, trade name Keytruda is a humanized antibody used in cancer immunotherapy. It targets the programmed cell death 1 (PD-1) receptor The drug was initially used in treating metastatic melanoma.

Pembrolizumab was invented by Gregory Carven, Hans van Eenennaam and John Dulos at Organon Biosciences which later became Schering Plough Research Institute and then Merck & Co. MRC Technology humanized the antibody pembrolizumab for Organon in 2006.

On September 4, 2014 the US Food and Drug Administration (FDA) approved pembrolizumab under the FDA Fast Track Development Program. It is approved for use following treatment with ipilimumab, or after treatment with ipilimumab and a BRAF inhibitor in advanced melanoma patients who carry a BRAF mutation. It is marketed by Merck.

https://en.wikipedia.org/wiki/Pembrolizumab

Now about Organon Biosciences

Organon was a pharmaceutical company headquartered in Oss, Netherlands. In November 2007, Schering-Plough Corporation, based in New Jersey, USA, acquired Organon, active pharmaceutical ingredient producer Diosynth (separate from Organon until 2004), and its veterinary pharmaceutical sister company Intervet from Akzo Nobel. In November 2009, Schering-Plough merged with Merck & Co. under the name Merck & Co., known as Merck Sharp & Dohme or MSD outside the United States and Canada.

https://en.wikipedia.org/wiki/Organon_International

[azurnoir]

12. Here's your post

Star Member King_David (13,375 posts)
9. All the Jewish Nobel winners are fake too I hear?

None of them have a Jewish blood line? Right ?



http://www.democraticunderground.com/1134121511


Pathetic ....I have to pinch myself to make sure I am not on some extremist right wing web site.....

http://www.democraticunderground.com/?com=view_post&forum=1134&pid=121582

[King_David]

14. Yep

[grossproffit]

11. Research in Israel led to the drug Keytruda

Keytruda – medicine which completely changes the approach to cancer treatment.

Recent research in Israel, led by Prof. Jacob Schachter (Head of “Ella”Institute, melanoma treatment and research, Sheba medical center, Tel Hashomer) successfully resulted in melanoma treatment. The drug, which has helped 50% of patients with metastatic melanoma with minimum side effects (in September 2014), was approved by the Ministry of Food and Drug Administration of America (FDA), under the accelerated procedure. Many experts suggest that this drug can lead to a real breakthrough in the treatment of cancer.

[url]http://www.resultmed.com/oncology-2/melanoma-and-skin-cancer-2/keytruda/[/url]

[King_David]

15. Thanks

I believe that the other poster is well and truly BUSTED

[grossproffit]

19. Just the usual "distortions, diversions and defamation" from the BDS crowd.

[azurnoir]

16. From an Israeli Drug company site the drug was invented in the Netherlands in 2006

now additional clinical uses may have been discovered in Israel but the drug itself has been around for 10 years

Pembrolizumab (formerly MK-3475 and lambrolizumab, trade name Keytruda is a humanized antibody used in cancer immunotherapy. It targets the programmed cell death 1 (PD-1) receptor The drug was initially used in treating metastatic melanoma.

Pembrolizumab was invented by Gregory Carven, Hans van Eenennaam and John Dulos at Organon Biosciences which later became Schering Plough Research Institute and then Merck & Co. MRC Technology humanized the antibody pembrolizumab for Organon in 2006.

On September 4, 2014 the US Food and Drug Administration (FDA) approved pembrolizumab under the FDA Fast Track Development Program. It is approved for use following treatment with ipilimumab, or after treatment with ipilimumab and a BRAF inhibitor in advanced melanoma patients who carry a BRAF mutation. It is marketed by Merck.

https://en.wikipedia.org/wiki/Pembrolizumab

Now about Organon Biosciences

Organon was a pharmaceutical company headquartered in Oss, Netherlands. In November 2007, Schering-Plough Corporation, based in New Jersey, USA, acquired Organon, active pharmaceutical ingredient producer Diosynth (separate from Organon until 2004), and its veterinary pharmaceutical sister company Intervet from Akzo Nobel. In November 2009, Schering-Plough merged with Merck & Co. under the name Merck & Co., known as Merck Sharp & Dohme or MSD outside the United States and Canada.

https://en.wikipedia.org/wiki/Organon_International

[King_David]

17. Pathetic....

[grossproffit]

24. Wikipedia is not considered a credible source or authoritative source

Wikipedia is increasingly used by people in the academic community, from freshman students to professors, as an easily accessible tertiary source for information about anything and everything. However, citation of Wikipedia in research papers may be considered unacceptable, because Wikipedia is not considered a credible or authoritative source

[url]https://en.wikipedia.org/wiki/Wikipedia:Academic_usep[/url]

[azurnoir]

27. aha especially when it ruins some good propaganda huh? I mean Carter reputed BDS supporter cured by

an Israeli miracle wow so rich it's fattening, but once again the wiki entries which are quite detailed

Pembrolizumab (formerly MK-3475 and lambrolizumab, trade name Keytruda is a humanized antibody used in cancer immunotherapy. It targets the programmed cell death 1 (PD-1) receptor The drug was initially used in treating metastatic melanoma.

Pembrolizumab was invented by Gregory Carven, Hans van Eenennaam and John Dulos at Organon Biosciences which later became Schering Plough Research Institute and then Merck & Co. MRC Technology humanized the antibody pembrolizumab for Organon in 2006.

On September 4, 2014 the US Food and Drug Administration (FDA) approved pembrolizumab under the FDA Fast Track Development Program. It is approved for use following treatment with ipilimumab, or after treatment with ipilimumab and a BRAF inhibitor in advanced melanoma patients who carry a BRAF mutation. It is marketed by Merck.

https://en.wikipedia.org/wiki/Pembrolizumab

Now about Organon Biosciences

Organon was a pharmaceutical company headquartered in Oss, Netherlands. In November 2007, Schering-Plough Corporation, based in New Jersey, USA, acquired Organon, active pharmaceutical ingredient producer Diosynth (separate from Organon until 2004), and its veterinary pharmaceutical sister company Intervet from Akzo Nobel. In November 2009, Schering-Plough merged with Merck & Co. under the name Merck & Co., known as Merck Sharp & Dohme or MSD outside the United States and Canada.

https://en.wikipedia.org/wiki/Organon_International

[grossproffit]

31. No, just a fact in the world of academia. One would not use Wikipedia as a source for research.

[King_David]

20. Israeli breakthrough helps cancer patients' bodies heal themselves

If the new treatment mechanism, known as immunotherapy, lives up to expectations, the world of oncology could undergo a real revolution within just a few years - meet Keytruda, Israeli drug for fighting metastatic melanoma.
Sarit Rosenblum


http://www.ynetnews.com/articles/0,7340,L-4571367,00.html

[King_David]

21. Breakthrough! Have The Israelis Developed A Cure For Cancer?

Israeli researchers have developed an entirely new approach towards fighting cancer - and a brand new drug that uses this approach with what appears to be amazing success.

The new approach is called immunotherapy and involves enhancing the body's natural immune systems to destroy the cancer cells. This is a 180 degree turn from contemporary methods like chemotherapy and radiation therapy,that seek to destroy the cancer cells and unfortunately usually end up destroying useful cells and even damaging organs, and producing harmful side effects as well.

Known as Keytruda, the drug that halted Ben-Shabbat's aggressive cancer is viewed today as the great hope for patients with metastatic melanoma, and just recently received US Food and Drug Administration approval. According to many experts in the field, Keytruda is likely to lead to a significant breakthrough in the treatment of cancer.



http://joshuapundit.blogspot.ca/2014/09/breakthrough-have-israelis-developed.html

[azurnoir]

29. and a blogger well okay once again wiki and I invite folks to check the citations too

Pembrolizumab (formerly MK-3475 and lambrolizumab, trade name Keytruda is a humanized antibody used in cancer immunotherapy. It targets the programmed cell death 1 (PD-1) receptor The drug was initially used in treating metastatic melanoma.

Pembrolizumab was invented by Gregory Carven, Hans van Eenennaam and John Dulos at Organon Biosciences which later became Schering Plough Research Institute and then Merck & Co. MRC Technology humanized the antibody pembrolizumab for Organon in 2006.

On September 4, 2014 the US Food and Drug Administration (FDA) approved pembrolizumab under the FDA Fast Track Development Program. It is approved for use following treatment with ipilimumab, or after treatment with ipilimumab and a BRAF inhibitor in advanced melanoma patients who carry a BRAF mutation. It is marketed by Merck.

https://en.wikipedia.org/wiki/Pembrolizumab

Now about Organon Biosciences

Organon was a pharmaceutical company headquartered in Oss, Netherlands. In November 2007, Schering-Plough Corporation, based in New Jersey, USA, acquired Organon, active pharmaceutical ingredient producer Diosynth (separate from Organon until 2004), and its veterinary pharmaceutical sister company Intervet from Akzo Nobel. In November 2009, Schering-Plough merged with Merck & Co. under the name Merck & Co., known as Merck Sharp & Dohme or MSD outside the United States and Canada.

https://en.wikipedia.org/wiki/Organon_International

[Scootaloo]

35. Short answer: No, they have not

Not anything about Israel. I just hate headlines that try to claim a "cure for cancer!" - it's biologically and medically unsound sensation journalism. There is no "cure for cancer." Cancer is a complex of diseases and conditions with different causes, different effects, and different treatments. Even very similar forms of cancer can have wildly different responses to a given treatment, because they're still only similar.

Off-topic, I guess, I just loathe the "OMG CANCER CURE!" journalism.

[King_David]

42. Great that BDS bigots failures helped president Carter fight off cancer....

[King_David]

22. Israeli-Researched Drug Helps Jimmy Carter Beat Cancer

A breakthrough Israeli-researched drug is credited for assisting former US President Jimmy Carter, a pro-Palestinian activist, in his battle with cancer.


http://www.jewsnews.co.il/2015/12/10/israeli-researched-drug-helps-jimmy-carter-beat-cancer/

[King_David]

23. This Israeli drug helped Jimmy Carter beat cancer

http://www.jta.org/2015/12/08/news-opinion/united-states/this-israeli-drug-helped-jimmy-carter-beat-cancer

[King_David]

25. Jimmy Carter Saved By Israeli Cancer Treatment

http://freebeacon.com/issues/jimmy-carter-saved-by-israeli-cancer-treatment/

[King_David]

26. Headquartered in Misgav, Israel, cCAM got off the ground in 2010

Headquartered in Misgav, Israel, cCAM got off the ground in 2010 with the help of the Israeli Office of the Chief Scientist's incubators program, developing CM-24 based on research done at Sheba Academic Medical Center Hospital. The biotech's investor syndicate includes OrbiMed, Pontifax and Arkin Holdings.

http://www.fiercebiotech.com/story/merck-signs-605m-deal-bulk-cancer-immunotherapy/2015-07-28

[azurnoir]

30. you must not read your own links BTW Keytruda's clinical trial ID was MK-3475 not CM-24

The New Jersey pharma giant has agreed to spend $95 million up front on cCAM Biotherapeutics and its lead asset, an early-stage treatment similar to Keytruda. Under the agreement, the biotech's shareholders are due as much as $510 million more tied to clinical, regulatory and commercial milestones, Merck said

http://www.fiercebiotech.com/story/merck-signs-605m-deal-bulk-cancer-immunotherapy/2015-07-28
i

[King_David]

32. Ha Ha ....pathetic

[azurnoir]

33. is that really the best you can do? but one more time

Pembrolizumab (formerly MK-3475 and lambrolizumab, trade name Keytruda is a humanized antibody used in cancer immunotherapy. It targets the programmed cell death 1 (PD-1) receptor The drug was initially used in treating metastatic melanoma.

Pembrolizumab was invented by Gregory Carven, Hans van Eenennaam and John Dulos at Organon Biosciences which later became Schering Plough Research Institute and then Merck & Co. MRC Technology humanized the antibody pembrolizumab for Organon in 2006.

On September 4, 2014 the US Food and Drug Administration (FDA) approved pembrolizumab under the FDA Fast Track Development Program. It is approved for use following treatment with ipilimumab, or after treatment with ipilimumab and a BRAF inhibitor in advanced melanoma patients who carry a BRAF mutation. It is marketed by Merck.

https://en.wikipedia.org/wiki/Pembrolizumab

Now about Organon Biosciences

Organon was a pharmaceutical company headquartered in Oss, Netherlands. In November 2007, Schering-Plough Corporation, based in New Jersey, USA, acquired Organon, active pharmaceutical ingredient producer Diosynth (separate from Organon until 2004), and its veterinary pharmaceutical sister company Intervet from Akzo Nobel. In November 2009, Schering-Plough merged with Merck & Co. under the name Merck & Co., known as Merck Sharp & Dohme or MSD outside the United States and Canada

https://en.wikipedia.org/wiki/Organon_International

[shira]

37. Would you personally boycott everything Israeli? I mean, everything. n/t

[azurnoir]

38. I would boycott everything settlements

[King_David]

28. Here’s why the drug that helped Jimmy Carter get ‘cancer-free’ is such a big deal

http://jewishnews.com/2015/12/08/heres-why-the-drug-that-helped-jimmy-carter-get-cancer-free-is-such-a-big-deal/

[azurnoir]

34. The article make no mention of Israel thanks

[R. Daneel Olivaw]

36. ...

Some just won't give up with the smoke and mirrors to cover apartheid.

[King_David]

41. Former-U.S. President Carter's cancer cured by Israeli drug

JTA - Keytruda, a new cancer drug that was researched and tested at the Sheba Medical Center in Ramat Gan, helped former President Jimmy Carter overcome his life-threatening case of melanoma.

http://www.haaretz.com/world-news/1.690966?v=3C5A8B48976FF1F471975568E3FBFBED


---------/-/----------

Put that in the BDS pipe and smoke it...

[azurnoir]

43. This is all political - ever hear of Gleevec? I worked in BMT at the U of mn when it was STI-571

and also being researched and tested there same as Keytruda with Israel, yet no one at the U of Mn is claiming it's a U of MN
drug, no political juice to be had there, sadly this is not the case with Keytruda the subtitle to your Haaretz article is

Keytruda, a new 'immunotherapy' drug researched and tested at Ramat Gan medical center, has helped Carter overcome melanoma.

read more: http://www.haaretz.com/world-news/1.690966?v=3C5A8B48976FF1F471975568E3FBFBED

most new drugs are researched and tested at more than one place-this all as I formerly said about BDS and Presidents Carters alleged support for it

really sad in way but in no way a surprise either

[King_David]

44. I don't think that wherever you claim you worked has any relevance to this whatsoever.

I think your pathetic attempt to refute fact that an Israeli drug helped save president Carter has been well and truly proved to be petty mean spirited nonsense- in this thread.

[azurnoir]

45. The only mean spiritedness here is using President Carter's remission as a political tool

against both him to make him appear hypocritical perhaps? and BDS and you can not deny this is the case it's in the person who posted this thread's editorial comment and your comment here

Star Member King_David (13,397 posts)
41. Former-U.S. President Carter's cancer cured by Israeli drug


JTA - Keytruda, a new cancer drug that was researched and tested at the Sheba Medical Center in Ramat Gan, helped former President Jimmy Carter overcome his life-threatening case of melanoma.

http://www.haaretz.com/world-news/1.690966?v=3C5A8B48976FF1F471975568E3FBFBED


---------/-/----------

Put that in the BDS pipe and smoke it...


http://www.democraticunderground.com/?com=view_post&forum=1134&pid=121656

[King_David]

46. Oh puleez there's so many links proving Israels involvement ...

Including that one from Haaretz....

But because you claimed to work somewhere or something like that, all the other links are wrong ?

Nobodies buying that nonsense.

Had the BDS bigots got there way this drug wouldn't have been around. And that's just fact....

[azurnoir]

47. none of links proved any thing other than the drug was tested and some research was done in Israel

but that most drugs are researched and tested at a number of locations is quite standard in the field of pharmacological research

[King_David]

49. LOL

Because you worked somewhere?

[azurnoir]

50. see comment #48 Keytruda (Pembrolizumab) was also researched and tested at Penn State

http://www.democraticunderground.com/?com=view_post&forum=1134&pid=121709

[King_David]

51. Did you work there too ?

[azurnoir]

52. Here's the direct link to Penn States site froom the comment you seem to be avoiding

for some reason


http://www.upenn.edu/pennnews/news/penn-medicines-new-immunotherapy-study-will-pit-pd-1-inhibitor-against-advanced-lung-cancer

oh and while we're here haven't you mentioned that you hold some medical position? I ask because I find it astounding that the what is routine in the testing of new drugs seems so foreign to you

[King_David]

53. While it's been amusing, this one person attempt on a forum to take the credit away from An Israeli

Institution for the drug used by President Carter in his fight against cancer .... I have now decided my amusement is over.

Bye

[azurnoir]

54. nothing taken from the institution I pointed out it was not an Israeli drug nor is it Penn States

drug either

[6chars]

55. Actually. Penn is different than Penn State

Penn is Ivy League, Penn State has a strong though recently tainted football tradition.

Of course medical research is not done in a single institution, but looking at the various reports, it seems clear that Israel was the key player in this breakthrough, other institutions did bits and pieces.

[azurnoir]

56. you're right University of Pennsylvania not Penn State

now as to who did what you're entitled to your opinion albeit politically motivated IMO, your dig at BDS in the OP shows that and had it not been for that along with the nasty implication towards President Carter I would not have said a word

[6chars]

57. you also seem to have me confused with another poster

I think even those who disagree with Carter on Israel/Palestine issues respect what he has done with his life. Here's to his next chapter, eh?

[azurnoir]

58. I thought you were the one who posted the thread

sorry about that

[azurnoir]

48. psst Keytruda (Pembrolizumab) was also tested and researched at Penn State

http://www.upenn.edu/pennnews/news/penn-medicines-new-immunotherapy-study-will-pit-pd-1-inhibitor-against-advanced-lung-cancer