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Eugene

(61,894 posts)
Wed Sep 13, 2017, 12:36 AM Sep 2017

Up to 7 years of hormone therapy is safe for postmenopausal women, new data show

Source: Los Angeles Times

Up to 7 years of hormone therapy is safe for postmenopausal women, new data show

By Melissa Healy

SEPTEMBER 12, 2017, 4:20 PM

For decades now, women navigating menopause have been buffeted by shifting research findings on the risks and possible benefits of hormone-replacement therapy. Now, a landmark clinical trial that followed more than 27,000 subjects for roughly 18 years has offered some conclusive evidence that neither the hype nor the grim warnings about hormone-replacement therapy were warranted.

In findings published Tuesday in the journal JAMA, women who were randomly assigned to take some form of hormone-replacement therapy for a median of six to seven years were no more, nor less, likely to die of any cause over the study’s duration than were women who had been assigned to receive a placebo treatment.

The women who got synthetic estrogen and progesterone hormones to replace their naturally declining levels were no more (nor less) likely than those who got a placebo to die of stroke or heart failure. And they were neither more nor less likely to die of cardiovascular disease or cancer.

University of Pittsburgh Dr. Melissa McNeil, who wrote an editorial appearing alongside the new findings, called them “both compelling and reassuring.”

-snip-


Read more: http://www.latimes.com/science/sciencenow/la-sci-sn-hormone-therapy-safe-20170912-story.html

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Related:
• Findings: Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality (JAMA)
• Editorial: Menopausal Hormone Therapy Understanding Long-term Risks and Benefits (JAMA)
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Up to 7 years of hormone therapy is safe for postmenopausal women, new data show (Original Post) Eugene Sep 2017 OP
Thanks for posting this, it's a substantial study flamingdem Sep 2017 #1
It definitely is not safe if a woman has Leiden Factor V, a blood clotting condition. blue neen Sep 2017 #2
Thanks for posting. MLAA Sep 2017 #3
Of course if someone has a breast cancer which is ER or PR positive, it would NOT be prudent to still_one Sep 2017 #4
That is especially good for women in surgical menopause Warpy Sep 2017 #5
Uh oh. I might be reaching the limit. Laffy Kat Sep 2017 #6
Reached that limit a couple of years ago CountAllVotes Sep 2017 #7
Bookmarking. Thanks for posting! n/t ms liberty Sep 2017 #8

flamingdem

(39,313 posts)
1. Thanks for posting this, it's a substantial study
Wed Sep 13, 2017, 12:42 AM
Sep 2017

and can put to rest some of the endless speculation and claims.

blue neen

(12,320 posts)
2. It definitely is not safe if a woman has Leiden Factor V, a blood clotting condition.
Wed Sep 13, 2017, 12:50 AM
Sep 2017

Huh-uh.

Pregnant women with Leiden Factor V have to take Lovenox (blood thinner) shots. Estrogen and blood clotting disorders don't go together well.

still_one

(92,190 posts)
4. Of course if someone has a breast cancer which is ER or PR positive, it would NOT be prudent to
Wed Sep 13, 2017, 12:53 AM
Sep 2017

supplement with Estrogen or Progesterone

Laffy Kat

(16,377 posts)
6. Uh oh. I might be reaching the limit.
Wed Sep 13, 2017, 02:47 AM
Sep 2017

They can have my HR pills when they pry them from my cold, dead fingers.

CountAllVotes

(20,869 posts)
7. Reached that limit a couple of years ago
Wed Sep 13, 2017, 03:35 AM
Sep 2017

Now called "estrogen intolerant" ...

Very god damned unpleasant at best!

If lucky they'll give you some sort of cream that might help, MIGHT.



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