Health
Related: About this forumNew Alzheimer's Treatment Clears Plaques From Brains of Mice Within Hours
Scientists have repaired a natural gateway into the brains of mice, allowing the clumps and tangles associated with Alzheimer's disease to be swept away.
After just three drug injections, mice with certain genes that mimic Alzheimer's showed a reversal of several key pathological features.
Within hours of the first injection, the animal brains showed a nearly 45 percent reduction in clumps of amyloid-beta plaques, a hallmark of Alzheimer's disease.
The mice had previously shown signs of cognitive decline, but after all three doses, the animals performed on par with their healthy peers in spatial learning and memory tasks. The benefits lasted at least six months.
https://www.sciencealert.com/new-alzheimers-treatment-clears-plaques-from-brains-of-mice-within-hours
multigraincracker
(38,053 posts)find a cure five years later.
He was a great scientist.
KS Toronado
(23,870 posts)And tells us we just need more vitamin A?
Bernardo de La Paz
(60,320 posts)international team of researchers, co-led by scientists at the Institute for Bioengineering of Catalonia (IBEC) and the West China Hospital Sichuan University (WCHSU).
karin_sj
(1,385 posts)IronLionZion
(51,554 posts)the worm might be making the decisions
Bengus81
(10,372 posts)no matter what that idiot does.
3Hotdogs
(15,548 posts)She made it to 98 so maybe she was on to something.
KS Toronado
(23,870 posts)and she also questioned doctors and took a lot of over-the-counter vitamins & meds.
dooner
(1,227 posts)UCSF does a lot of medical research and clinical trials in Northern California. Research funding cuts were announced yesterday, including Alzheimer's research.
https://www.sfgate.com/bayarea/article/ucsf-staff-cuts-deepen-threaten-drug-research-21098563.php
NNadir
(38,549 posts)...an inflammatory syndrome, certainly related to the described mechanism.
This said the history of Alzheimer's treatments and theory are littered with false starts and even fraud, the famous Lesne case being the most famous, again involving mice, albeit with doctoring images of Western blots.
This is not to say this work is suspect; it may be very good, even a "breakthrough," to use that oft abused word, but it will need to be shown to be replicable in many labs to confirm the finding.
As science in this country is now subject to willful vandalism by ignoramuses, the prospect does not look promising.
mucifer
(25,729 posts)Fla Dem
(27,774 posts)JustABozoOnThisBus
(24,726 posts)in one ear, out the other, sawing motion, easy-peasey. Or, just use worms.
RainCaster
(13,888 posts)Or the occasional dead whale found on a beach.
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