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Sat Dec 3, 2022, 02:18 PM

Has anyone gone through Cymbalta (Duloxetine) withdrawal?


I've been taking it for post-shingles neuralgia for a couple of years, but due to an unfortunate confluence of events, I'm facing my last daily dose tomorrow. It may be another week, or more, before I can get my prescription refilled.

I'm wondering if anyone here has gone through withdrawal after taking the med for an extended time. Sounds like I'm in for a *not good* week or so.

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Reply Has anyone gone through Cymbalta (Duloxetine) withdrawal? (Original post)
LudwigPastorius Dec 3 OP
emulatorloo Dec 3 #1
LudwigPastorius Dec 3 #3
emulatorloo Dec 3 #5
GPV Dec 3 #2
LudwigPastorius Dec 3 #4
emulatorloo Dec 3 #6
shenmue Dec 3 #7
LudwigPastorius Dec 3 #8
I_UndergroundPanther Dec 4 #9
LudwigPastorius Dec 4 #10

Response to LudwigPastorius (Original post)

Sat Dec 3, 2022, 05:08 PM

1. Yes and it is horrible. You need to taper off, not go cold turkey.

Do whatever you can to get your refill as soon as possible. I suggest you call your Docís office ASAP and explain the situation.

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Response to emulatorloo (Reply #1)

Sat Dec 3, 2022, 07:04 PM

3. Thanks for responding.


I'll have to try to get in contact with them Monday morning.

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Response to LudwigPastorius (Reply #3)

Sat Dec 3, 2022, 07:13 PM

5. Of course! Hang in there and keep us posted.

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Response to LudwigPastorius (Original post)

Sat Dec 3, 2022, 06:09 PM

2. It was so painful I cried myself to sleep for a week.

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Response to GPV (Reply #2)

Sat Dec 3, 2022, 07:07 PM

4. Yikes.


Sorry about that.

I'm in between doctors. The old one retired 6 months ago, and the earliest I can see the new one is on the 22nd.

Looks like I'm in for a nice long Monday morning on "hold" waiting to talk to somebody.

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Response to GPV (Reply #2)

Sat Dec 3, 2022, 07:15 PM

6. I hid in my computer room because I was so terrified of everything.

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Response to LudwigPastorius (Original post)

Sat Dec 3, 2022, 08:18 PM

7. Health to you

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Response to shenmue (Reply #7)

Sat Dec 3, 2022, 09:01 PM

8. Thanks!

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Response to LudwigPastorius (Original post)

Sun Dec 4, 2022, 12:32 AM

9. I took it over 2 years

For some reason I had no withdrawal symptoms. Tapered it off. A little depression,because it has anti depressant effects. My meds got adjusted and I was ok.

My pain came back tho like it was before the cymbalta,but luckily it was time to redo my back shots.
The pain got under control.

Been off cymbalta ever since and Im doing ok.

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Response to I_UndergroundPanther (Reply #9)

Sun Dec 4, 2022, 01:08 PM

10. Glad you're OK.

Like most of the other things prescribed for me, cymbalta worked great for the first 6 -8 months at relieving my pain, but it has gradually been losing effectiveness since then.

It'll probably be good for me to go off of it for awhile, if I can manage the pain with Tylenol and keep from going into too deep of a mood hole.

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