Rep. Jared Polis, D-Colo., wants Attorney General Eric Holder to confirm that the federal approach to state-licensed recreational marijuana stores, set to open next year in Colorado and Washington state, will be similar to the Justice Department's approach to medical marijuana dispensaries.

"Stores are opening next year," Polis told U.S News. "We would like to have the clarification from the attorney general to make it clear that the Ogden memo also applies" to recreational marijuana stores.

The Ogden memo is a 2009 document written by then-Deputy Attorney General David Ogden that says it wouldn't be an "efficient use" of federal resources to go after medical marijuana patients. It also said the Justice Department would primarily target dispensaries that commit other infractions, such as selling hard drugs, using guns or breaking state marijuana regulations.

Polis says the Justice Department has misled the states into believing a policy announcement was imminent for the past eight months.

The National Institute on Drug Abuse released an eyebrow-raising statement to PolitiFact on Monday, denying that marijuana is less toxic than alcohol.

"Claiming that marijuana is less toxic than alcohol cannot be substantiated since each possess their own unique set of risks and consequences for a given individual," wrote the institute. NIDA, part of the National Institutes of Health, funds government-backed scientific research and has a stated mission "to lead the nation in bringing the power of science to bear on drug abuse and addiction."

The statement was in response to a declaration by the pro-pot policy group Marijuana Policy Project that marijuana is less harmful than alcohol –- a claim that was the centerpiece of a controversial pro-marijuana commercial aired during a NASCAR race last month.

PolitiFact took the claim to task, comparing marijuana-related deaths to alcohol-related deaths and toxicity levels of the two substances.

An ad from the Marijuana Policy Project claims marijuana is "less toxic" than alcohol.

Our job as fact-checkers in this case is not to decide whether marijuana is good or harmful. We're focused on whether the drug in its natural form is "less toxic" than alcohol.

In that regard, science and statistics present a strong case:

Deaths or even trips to the hospital are much more likely due to alcohol;
Scientists could not find any documented deaths from smoking marijuana;
A study found the safety ratio for marijuana (the number of doses to cause death) is much greater than compared to alcohol. Put another way, marijuana is 100 times less toxic than alcohol.

Overall, we rate this claim Mostly True.

It's been over 40 years since President Nixon declared war on drugs and more than a quarter-century since Congress first enacted mandatory minimum sentences for drug offenses, leading to a ballooning U.S. prison population. We, the land of the free and the home of the brave, have become the world's biggest jailer. In the light of Uruguay and New Zealand's recent efforts toward relaxing their drug laws, the time seems right for the United States to do some reform of its own. Specifically, the United States should reform its mandatory minimum sentencing policies for non-violent drug offenders.

The policy arguments are well known and indisputable: these laws disproportionately impact minorities, overcrowd our prison system, hamstring our judges, don't deter crime, and are a waste of money. These arguments have been around for decades. What makes this time different — because in Washington, policy is often trumped by politics — is the surprising amount of bipartisan consensus around this issue. Republican and Democrats both agree: now is the time to reform our drug sentencing laws.

Right now there are two bills in the Congress that would go a long way toward reforming our drug sentencing laws. Last week, Senators Mike Lee (R-Utah) and Dick Durbin (D-Ill.) introduced the Smarter Sentencing Act, which would allow judges more of the leeway that they have asked for to sentence criminals below the mandatory minimum sentence. The bill would also lower the mandatory minimum sentences for various drug crimes. The Justice Safety Valve Act, sponsored by Senators Rand Paul (R-Ky.) and Patrick Leahy (D-Vt.), and by Congressmen Robert Scott (D-Va.) and Thomas Massie (R-Ky.), would go even further, eliminating mandatory sentences for some non-drug crimes. Either bill would be a positive step towards creating more-just sentencing laws by returning discretion to judges.

Support for reform has been building for some time. One precedent to look at is the Fair Sentencing Act of 2010, which reduced the disparity in minimum sentences between powder cocaine and crack cocaine from 100-1 down to 18-1. That bill was supported by several influential House Republicans such as James Sensenbrenner (Wisc.), Paul Ryan (Wisc.), former Rep. Ron Paul (Texas), and even Todd Akin (formerly R-Mo.). That act proved that not only can drug reform be bipartisan, it can also attract strong conservative support.

Attorney General Eric Holder is rumored to be proposing major reforms to drug sentencing in the coming weeks, and if a Wednesday interview with NPR is any indication, the changes could signal a pivot from the aggressive policies embraced by the Justice Department.

"I think there are too many people in jail for too long, and for not necessarily good reasons," Holder said in the interview, turning from the department's highly criticized crackdown on drug law enforcement. As NPR noted, almost half of the people in federal prison are serving time for drug charges.

"The war on drugs is now 30, 40 years old," he continued. "There have been a lot of unintended consequences. There's been a decimation of certain communities, in particular communities of color."

Holder hinted in the interview that the changes could include better prioritization of federal law enforcement and shortened sentences for minor drug offenses. According to NPR, Holder could announce his proposal as early as next week in a speech to the American Bar Association in San Francisco.

The survey project is part of an HHC effort in alliance with the University of the City of London and the drug policy research group the Beckley Foundation, to compile a database based on the survey results that will let medical cannabis users look up which strains of cannabis are most commonly preferred to treat particular ailments.

HHC and its partners plan to key the questionnaire answers to the results of the extensive tests HHC has already done to categorize the various types of cannabis that come through their facility. The cannabis study project is still in its early data collection phase, but the hope is that the eventual result will be an easily accessible categorization of each strain of cannabis, and its customer preference status in treating each particular health problem.

...HHC’s survey takes into account not only the strain of cannabis each patient is using and evaluating, but also the particular batch of cannabis and the unique cannabinoid profile.

In theory, he says, over the course of two, three, four years of implementing questionnaire responses, the resulting database will allow the user to ask things like: “What did the largest number of multiple sclerosis patients prefer? Which strain did they prefer least? What’s the chemical difference—what’s the difference in cannabinoid profile between those two different strains of cannabis? So that we can start developing an actual, objective way of at least identifying cannabinoid profile with symptoms.”

The shop, located on N. Capitol Street, NW just north of New York Avenue, is only 2.5 miles from the White House and the rest of the city center. Patients with certain qualifying conditions including cancer, glaucoma, muscle spasms and HIV/AIDS will be able to purchase cannabis at the shop.

The shop represents a battle that has been long and drawn out in our nation's capitol. Voters approved medical cannabis in 1998, but the U.S. Congress (which has to approve changes to D.C. law) prevented that from happening for nearly 11 years. In 2009 the city began the process of registering and licensing patients but it's been a lengthy four years to get dispensaries off the ground as many lawmakers feared federal intervention (and federal jail time) for implementing the will of the voters.

Unfortunately, Washington D.C. does not allow for reciprocity with other state medical marijuana programs. So medical cannabis patients from any of the 50 state surrounding the city are still sadly considered criminals.

The opening is sure to get more publicity over the next few weeks, which might actually get politicians to pay attention to the fact that medical cannabis is almost literally at their doorsteps.

--Nationally, there is little apparent relationship between increasing marijuana arrests and rates of use.

Marijuana arrests have nearly doubled from 1991 to 2009, increasing by 150% during the 1990s and increasing steadily in recent years, producing an annualized change of 6.56% per year during this period.

Overall, levels of marijuana use in the United States have remained fundamentally unchanged during this period. Population estimates of annual marijuana use, for example, have remained relatively constant over the last five years at approximately 25 million individuals.

From 2003 to 2007, the number of annual marijuana arrests increased by 2.93% per year, while the number of annual marijuana users decreased by 0.21% per year.

The overall marijuana arrest rate of between 3% and 6% of users is not enough to represent a meaningful deterrent.

--Young people and African-Americans are disproportionately affected by marijuana arrests.

Males aged 15 to 24 account for 52% of all marijuana arrests. While the national rate of marijuana possession arrests is 248 per 100,000, the arrest rate for males aged 15 to 19 is 1,911 per 100,000.

While the marijuana-use rate for African-Americans is only about 25% greater than for whites, the marijuana possession arrest rate for blacks is three times greater. This is not a regional disparity, but is seen in every state and most counties.

---The costs of arresting marijuana users are substantial, and raise serious questions about the cost effectiveness of marijuana prohibition.

Using the same method of calculation used by the White House Office of National Drug Control Policy, marijuana arrests cost state and local governments $10.3 billion in 2006.

Marijuana arrests represent 6% of all arrests. In many states, they represent the fifth, sixth, or seventh largest category of arrests.

The clearance rate (i.e. the percentage of crimes solved by arrest) for murder, rape, robbery, assault, burglary, larceny, and motor vehicle theft was 26% in 2007, meaning that no one is arrested for three quarters of these serious crimes. In this environment, time and resources spent on roughly 850,000 marijuana arrests per year represent a significant opportunity cost.

In California, decriminalization of marijuana possession saved taxpayers $857 million in 2006 (details in the California state report (PDF)) -- this pdf is linked at the link.

(Uruguay) provides, significantly, a model for how to engage in debate over marijuana policy in a mature and responsible way. When President Mujica first issued his proposal last June, he made clear that he welcomed vigorous debate over both its merits and the particulars. International experts were invited from abroad for intensive discussions with people from all walks of civil society and government. A range of specific proposals were considered, all with an eye toward transforming an illegal industry into a legal one to better protect public safety and health. Political rhetoric and grandstanding permeated the debate, as would be expected in any vibrant democratic process, but substantive issues dominated.

What I as an American find most striking about Uruguay’s historic move is the demonstration of political leadership by President Mujica. In the United States, marijuana policy reform is an issue on which the people lead and the politicians follow. Colorado and Washington changed their laws through the ballot initiative process, with roughly 55% of voters supporting the reform, while most elected officials sat on the sidelines. Even today, with a majority of Americans in favor of legalizing marijuana, not one U.S. governor or U.S. senator is prepared to publicly support the legalization of marijuana (apart from the governors of Washington and Colorado who now are obliged to implement the new laws in their states). By contrast, when President Mujica made his proposal, he reportedly did it without consulting any polls or political consultants; he simply listened to respected experts about what the optimal marijuana policy would be – and then said, let’s do it.

President Mujica is not the only Latin American leader to demonstrate courage in calling for alternatives to the drug war. Presidents Juan Manuel Santos of Colombia and Otto Pérez Molina of Guatemala have boldly demanded that legalization, decriminalization and other alternatives to ineffective, costly and destructive prohibitionist drug policies be considered. More recently, OAS Secretary General José Miguel Insulza has catapulted regional discussion of drug policy to an intellectual level unprecedented among multilateral organizations. But President Mujica’s proposal is unique in changing not just public debate but also actual laws and policies.

All this serves as a wake-up call for Europe, which was at the forefront of global drug policy reform in the latter part of the 20th century but has now been leapfrogged by developments in the Americas. Serious proposals for legal regulation of marijuana are proliferating in countries like Switzerland, Spain, the Czech Republic, Denmark and the Netherlands. And in Morocco, long one of the world’s leading producers of marijuana, legalization proposals are now being taken seriously by the national government.