Hollywood Lies, in rerun television ARE Autrocities on Native Americans!

[haele]

15. There is a theory that the Portuguese had been fishing off the Outer Banks since around 1000 CE

and they might have set up a arrangement with one or several native traders that were already used to trading up and down the Eastern Seaboard for the ability to come ashore at neutral ground and salt their cod for the trip back in exchange for a share of the fish.
Those native traders would likely have a stronger immune system and be able to deal with the Europeans without much of an issue, especially since the Portuguese who would have survived the fishing trip would not be bringing that much live virii or bacteria with them, or leave European goods lying around that could be carrying those virii or bacteria.

Haele