Anyone else looking at the Modera and Pfizer Vaccine pressers? They're not very controlled at all

[muriel_volestrangler]

22. What you call a "controlled infection process" is very rare, and not what "control" means in tests

I suspect you're thinking of a "challenge" process:

Human challenge studies provide a faster way to test vaccines because you don't have to wait for people to be exposed to an illness naturally.

Researchers would first use controlled doses of the pandemic virus to discover what is the smallest amount that can cause Covid infection in volunteers aged 18 to 30.

These human guinea pigs, who will be infected with the virus through the nose and monitored around the clock, have the lowest risk of harm due to their young age and good health.

Next, scientists could test if a Covid vaccine prevents infection.

https://www.bbc.co.uk/news/health-54612293

Very rare to do this with a disease that has serious consequences, as the article notes.

"just send people out in the public to get the virus after being vaccinated and that's it" is normal for phase 3 trials. You vaccinate some, give some a placebo, and see how many of each get infected in normal life. The "control group" is the ones with the placebo; you compare their rate of infection (for whom you have done nothing) with thoser who got the real vaccine.