it in my post. To underline, researchers have found that culture's usually much stronger than basic wirings (which themselves vary greatly), but all the very complex dynamics that affect personality and behavior can come into play to different degrees.
Here in rural GA I know a number of lifelong conservatives who talk and vote conservative but I feel confident would be liberal if they grew up in a blue community -- because of their tolerance and acceptance of differences and, as Jane Austen put it, of a "liberality of ideas." That's compared to those I believe would be conservative anywhere.
How many times have we read about people surprising their friends by "changing horribly" -- over time, or got a new girlfriend, moved from Boston to Oklahoma City, discovered Trump, developed the wisdom to realize liberals were wrong about almost everything, etc. They didn't have a brain transplant. They matured, developed awareness and connected with forums and new friends who gave them validation.
"I'm not saying we don't need an opposition party. But I don't see why we should support any efforts, even rhetorical, to save the GOP from the consequences of its own destructive and even treasonous behaviors." Didn't know anyone was, but of course there must be some somewhere. Not me. I agree with you there, andt he various prescriptions for the grave problem of the GOP are now usually, as Elizabeth Bennett said, "in fact...quite the opposite." 
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